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35 Cards in this Set
- Front
- Back
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Thiazide diuretics examples |
1st line choice chlorothiazide chlorthaidone HCTZ indapamide metalazone |
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Thiazide diuretics MOA |
increase excretion of Na+ and H2O reduce morbidity and mortality |
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Thiazide considerations |
screen for sulfa allergy Labs (can cause) hypokalemia hypomagnesemia hyponatremia hypercalcemia hyperglycemia |
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What HTN drug do you need to screen for allergy? And allergy to what? |
thiazide diuretics Sulfa allergy |
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ACE inhibitor examples |
Prils enalapril lisinopril fosinopril ramipril |
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ACE MOA |
cause vasodialation block Na+ and H2O retentian |
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ACE considerations |
contraindicated in pregnancy don't use if K+ greater than 5.5 (can cause hyperkalemia) |
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What HTN med is contraindicated in pregnancy |
ACE ARB |
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ACE SE |
cough rash taste disturbance hyperkalemia renal impairment |
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What HTN med can cause hyperkalemia |
ACE ARB direct renin inhibitor |
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ARB examples |
Sartans |
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ARB MOA |
cause vasodilation block Na+ and H2O absorption |
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ARB considerations |
contraindicated in pregnancy don't use with ACE |
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ARB SE |
cough hyperkalemia headache taste disturbance renal impairment |
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CCB examples |
verapamil diltiazem amlodipine felodipine nifedipine |
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CCB monitoring |
heart rate (esp with verapamil and diltiazem) |
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CCB uses |
angina arrythmias migraines HTN |
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CCB SE |
HA Flushing Bradycardia |
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B-blocker examples |
Lols atenolol carvedilol propranolol timolol |
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B-blocker MOA |
directly relax the heart |
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Uses for B-blockers |
HTN angina arrhythmias Not first line for HTN |
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B-blocker use considerations |
monitor HR avoid in COPD |
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B-blocker SE |
dizziness bradycardia heart block fatigue insomnia |
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Peripheral alpha-1 antagonist examples |
Zosins prazosin terazosin doxazosin |
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peripheral alpha-1 antagonist considerations |
Adjunct therapy take 1st dose at HS may cause syncope dry motuh orthostasis dizziness headache |
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Central alpha-2 agonist examples |
clonidine methyldopa |
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central alpha-2 agonist MOA |
prevent vasoconstriction cause vasodilation slow heart rated |
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central alpha-2 agonist considerations |
adjunct therapy do not discontinue abruptly drug of choice in pregnancy |
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What is the HTN drug of choice in pregnancy |
central alpha-2 agonist methyldopa |
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SE central alpha-2 agonist |
dry mouth sedation depression HA bradycardia |
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Arterial vasodilators examples |
hydralazine minoxidil |
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arterial vasodilator MOA |
directly relax the vascular smooth muscle resulting in arterial vasodilation |
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arterial vasodilator considerations |
adjunce reflex tachy |
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Direct renin inhibitors examples |
aliskiren |
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direct renin inhibitor MOA |
inhibitsrenin decreasesplasma renin activity inhibits conversion of angiotensinogen to angiotensin I |
