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196 Cards in this Set

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What are the two steps of focusing?
We focus images on the retina by changing the shape of the lens to keep focal length constant. (accomodation)
Crystallins are responsible for the focusing power of the lens.

1. Light rays from a source are refracted when they reach the lens of the eye.
2. The rays are then focused onto a single point
Look at pg 575, fig 17-9.
Vibration of tympanic membrane converts sound waves into...
Mechanical movements
pg 587
Parts and steps involved in gustation...(taste)
Taste Receptors/Taste buds- Montitored by:
Facial nerve VII- on anterior 2/3 of tongue. Glossopharyngeal nerve IX- Posterior 1/3 of tongue including the circumvallate. Vagus Nerve X- scattered on surface of epiglottis. Then they synapse within the solitary nucleus of the medulla oblongata and then on to the thalamus and the primary sensory cortex.
pg 564
Parts and steps involved in olfaction...(smell)
When you inhale, the air swirls within your nasal cavity to the olfactory epehelium. When the axons leave it, 20 bundles penetrate the cribriform plate of the ethmoid to reach the olfactory bulbs or cerebrum (synapse). Then travel along the olf tract to the olf cortex, the hypothalamus and portions of the limbic system.
Olf-only one that reaches the cortex directly!
pg 563
Parts and steps involved in photoreception...
It begins when a photon strikes the retinal portion of rhodopsin molecule.
Step 1- Opsin is activated.
Step 2- Opsin Activates Transduin, which in turn activates phosphodiesterase
Step 3- Cyclic-GMP levels decline and gated sodium channels close.
Step 4- The dark current is reduced and the rate of neurotransmitter relase declines.
Pg 581
Parts and steps involved in balance...
balance: Equilibrium sensations are provided by receptors of the vestibular complex - hair cells, which provide information about the direction and strength of mechanical stimuli.• The vestibular receptors activate sensory neurons of the vestibular ganglia. The axons form the vestibular branch of the vestibulocochlear nerve (VIII), synapsing within the vestibular nuclei. • The reflexive motor commands issued by the vestibular nuclei are distributed to the motor nuclei for cranial nerves involved with eye, head, and neck movements
pg 589
balance:look at last paragraph-numbers1-4
Parts and steps involved in hearing...
The receptors of the cochlear duct provide a sense of hearing that enables us to detect the quietest whisper, yet remain functional in a noisy room.

•Step 1: Sound waves arrive at the tympanic membrane. The orientation of the canal provides some directional sensitivity.

• Step 2: Movement of the tympanic membrane causes displacement of the auditory ossicles. When the tympanic membrane vibrates, so do the malleus and, through their articulations, the incus and stapes. In this way, sound is amplified.
Step 3: Movement of the stapes at the oval window establishes pressure waves in the perilymph of the vestibular duct.
•Step 4: The pressure waves distort the basilar membrane on their way to the round window of the tympanic duct. The location of maximum distortion varies with the frequency of the sound. Information about frequency is translated into information about position along the basilar membrane.
•Step 5: Vibration of the basilar membrane causes vibration of hair cells against the tectorial membrane. This movement leads to the displacement of the stereocilia, which in turn opens ion channels in the hair cell membranes. The resulting inrush of ions depolarizes the hair cells, leading to the release of neurotransmitters and thus to the stimulation of sensory neurons. The number of hair cells responding in a given region of the organ of Corti provides information on the intensity of the sound.
•Step 6: Information about the region and intensity of stimulation is relayed to the CNS over the cochlear branch of the vestibulocochlear nerve (VIII). The sensory neurons are located in the spiral ganglion of the cochlea. From there, the information is carried by the cochlear branch of cranial nerve VIII to the cochlear nuclei of the medulla oblongata for subsequent distribution to other centers in the brain.
Figure 17-30
Pg 596
Characteristics and functions of: hair cells
They are the basic receptors of the inner ear,which provide information about the direction and strength of mechanical stimuli.
Hair cells do not actively move their kinocilium or stereocilia; instead external forces push these processes and distort the cell membrane.
pg 589
Function of inner ear
contains receptors in the saccule and utricle that provide sensations of gravity and linear acceleration.
pg 588
Function of middle ear
It communicates with the nasopharynx via the auditory (pharyngotympanic) tube.
•Vibration of the tympanic membrane converts arriving sound waves into mechanical movements.
pg 586
Functions of the Outer Ear:
collects the sound waves and transports them through the external acoustic meatus to the tympanic membrane.
pg 585
Function and general characteristics of: endocrine system
Releases chemical messengers into the body that affects its activities. Preserves homeostasis by coordinating and regulating the activities of other cells, tissues, organs and systems. Regulates growth and development.

It includes all the endocrine cells and tissues of the body that produce hormones or paracrine factors with effects beyond their tissues of origin.
pg 606
definition and characteristics of: alarm phase
"fight or flight"
An immediate response to stress occurs- Directed by sympathetic division of the autonomic nervous system.

Characteristics-
1. increased mental alertness
2. increased energy consumption
3. mobilization of energy reserves (glycogen and lipids)4. changes in circulation: increased blood flow to skeletal muscles, decreased blood flow to the skin, kidneys, and digestive organs
5. drastic reduction in digestion and urine production
6. increased sweat gland secretion
7. increases in blood pressure, heart rate, and respiratory rate
pg 641
Functions of the Outer Ear:
collects the sound waves and transports them through the external acoustic meatus to the tympanic membrane.
pg 585
Function and general characteristics of: endocrine system
Releases chemical messengers into the body that affects its activities. Preserves homeostasis by coordinating and regulating the activities of other cells, tissues, organs and systems. Regulates growth and development.

It includes all the endocrine cells and tissues of the body that produce hormones or paracrine factors with effects beyond their tissues of origin.
pg 606
definition and characteristics of: exhaustion phase
Collapse of vital systems. May be caused by exhaustion of lipid reserves, failure of electrolyte balance, or inability to produce glucocortoroids.
pg 641
definition and characteristics of: hormone
Chemical messenger that is released in one tissue and transported in the bloodstream to alter the activities of specific cells in other tissues.
They circulate freely or are bound.
pg 604
definition and characteristics of: alarm phase
"fight or flight"
An immediate response to stress occurs- Directed by sympathetic division of the autonomic nervous system.

Characteristics-
1. increased mental alertness
2. increased energy consumption
3. mobilization of energy reserves (glycogen and lipids)4. changes in circulation: increased blood flow to skeletal muscles, decreased blood flow to the skin, kidneys, and digestive organs
5. drastic reduction in digestion and urine production
6. increased sweat gland secretion
7. increases in blood pressure, heart rate, and respiratory rate
pg 641
function of hormone: CT
Gland: Thyroid

Decrease Ca2+ concentrations in the body fluids;
Increase Ca2+ deposition in the bone; important regulator of
Ca2+ concentrations in body fluids during childhood and
pregnancy
hormone list
definition and characteristics of: exhaustion phase
Collapse of vital systems. May be caused by exhaustion of lipid reserves, failure of electrolyte balance, or inability to produce glucocortoroids.
pg 641
function of hormone: PTH (Parathyroid hormone)
Gland: Parathyroid

Increase the Ca2+ concentrations in body fluids; Dissolve
Ca2+ concentration from bone; reduces calcium deposition in
the bone; reduces urinary excretion of Ca2+; stimulates
formation of calcitriol
hormone list
definition and characteristics of: hormone
Chemical messenger that is released in one tissue and transported in the bloodstream to alter the activities of specific cells in other tissues.
They circulate freely or are bound.
pg 604
function of hormone: CT
Gland: Thyroid

Decrease Ca2+ concentrations in the body fluids;
Increase Ca2+ deposition in the bone; important regulator of
Ca2+ concentrations in body fluids during childhood and
pregnancy
hormone list
function of hormone: Glucocortoroids:
Coritsol, Cortisone, corticosterone
Gland: Adrenal Cortex

Accelerate glucose synthesis and glycogen formation;
glucose-sparing effect;
anti-inflammatory effect;
release amino acids from skeletal muscles
hormone list
function of hormone: epinephrin and norepinephrin
Gland: Adrenal Medulla

Increase: blood glucose, blood glycerol, fatty acids,
heart rate, blood pressure, breathing rate.
hormone list
function of hormone: PTH (Parathyroid hormone)
Gland: Parathyroid

Increase the Ca2+ concentrations in body fluids; Dissolve
Ca2+ concentration from bone; reduces calcium deposition in
the bone; reduces urinary excretion of Ca2+; stimulates
formation of calcitriol
hormone list
function of hormone: Glucocortoroids:
Coritsol, Cortisone, corticosterone
Gland: Adrenal Cortex

Accelerate glucose synthesis and glycogen formation;
glucose-sparing effect;
anti-inflammatory effect;
release amino acids from skeletal muscles
hormone list
function of hormone: insulin
Gland: Pancreas

Lowers blood glucose by—accelerating: glucose
uptake, glucose utilization and enhanced ATP
production; stimulating: glycogen formation, amino
acid absorption and protein synthesis, triglyceride
formation
hormone list
function of hormone: epinephrin and norepinephrin
Gland: Adrenal Medulla

Increase: blood glucose, blood glycerol, fatty acids,
heart rate, blood pressure, breathing rate.
hormone list
function of hormone: insulin
Gland: Pancreas

Lowers blood glucose by—accelerating: glucose
uptake, glucose utilization and enhanced ATP
production; stimulating: glycogen formation, amino
acid absorption and protein synthesis, triglyceride
formation
hormone list
Resistance Phase
Long term metabolic adjustments.
If stress is longer than 2 hrs, its this.

secretions acheive:
1. mobilization of remaining lipid and protein reserves
2. conservation of glucose for neural tissues
3. elevation and stabilization of blood glucose concentrations
4. conservation of salts and water, and the loss of K+ and H+.
Pg 641
function of Glucagon
gland: pancreas

Increases blood glucose by—stimulating: glycogen
breakdown, triglyceride breakdown, glucose
production
Hormone List
function of EPO (Erythropoietin)
gland: Kidney

Stimulate the production of red blood cells
Hormone List
function of Angiotenin II
gland: Lungs

Stimulates: adrenal production of aldosterone,
pituitary to secrete antidiuretic hormone (ADH)
Hormone List
function of ANP (Atrial natriuretic peptide)
gland: heart

Promotes the loss of Na+ and water; inhibits the
secretion of renin, antidiuretic hormone (ADH) and
Aldosterone; suppresses thirst; blocks actions of
angiotensin II or norepinephrine on arterioles
Hormone List
function of ADH (Antidiuretic hormone)
gland: posterior pituitary

Reduce water excretion, vasoconstricter (constrict peripheral
blood vessels); elevate blood volume and pressure
Hormone List
function of T3 & T4
gland: thyroid

Speed up the Kreb’s cycle; increase protein synthesis, oxygen
consumption, growth; stimulates development of the nervous
system.
Hormone List
function of GH (growth hormone)
gland: anterior pituitary

Stimulates cell growth, replication and protein
synthesis. Stimulates lipid mobilization and
catabolism.
Hormone List
function of Testosterone
gland: Testes

Production of functional sperm; maintain secretory
glands of male reproductive tract; stimulates: growth,
protein synthesis and muscle growth; determine male
secondary sexual characteristics; produce aggressive
behavioral responses
Hormone List
function of Estrogen
gland: ovaries

Steroid hormone: support the maturation of oocytes,
female secondary sexual characteristics, associated
behaviors; growth of uterine lining
Hormone List
What are four patterns of hormonal interaction
1. antagonistic (opposing) effects
2. synergistic (additive) effects
3. permissive effects, in which one hormone is necessary for another to produce its effect
4. integrative effects, in which hormones produce different, but complementary, results
Pg 638
Stress response (GAS) - what is it for
•Our bodies respond to a variety of stress-causing factors through the general adaptation syndrome (GAS), or stress response.
pg 640
function of: cardiovascular system
To transport materials to and from cells: oxygen and carbon dioxide, nutrients, hormones, immune system components, waste products
pg 651
function of blood
1. Transportation of dissolved gases, nutrients, hormones and metabolic wastes.
2. Regulation of PH and ion concentration of interstitial fluids
3. restriction of fluid losses at injury sites
4. defense against toxins and pathogens
5. stabilization of body temperature.
pg 651
characteristics and functions of: immunoglobulins
Also called antibodies.
Transport globulins (small molecules):
They attack foreign proteins and pathogens.
pg 654
functions and characteristics of: RBC
Most abundant blood cells (99%)
It gives whole blood its deep red color because of heme.
The heme binds and transports oxygen and carbon dioxide. Less than half blood volume. 1/3 of all human cells. lifespan is 120 days. Have no nucleus or organelles.
pg 655
functions and characteristics of: WBC
Also called leukocytes
Do not have hemoglobin
Have nuclei and other organelles
6000 to 9000 per microliter
Most WBCs in connective tissue and proper lymphatic system organs
They Defend against pathogens, Remove toxins and wastes, Attack abnormal cells
pg 666
functions and characteristics of: Platelets
Cell fragments involved in human clotting system.
Fx: Release important clotting chemicals
Temporarily patch damaged vessel walls
Actively contract tissue after clot formation.
150,000 to 500,000 per microliter
Circulates for 9–12 days
Are removed by spleen
2/3 are reserved for emergencies
pg 672
Structure of hemoglobin
4 globular protein subunits: α2β2 - alpha and beta chains
each with 1 molecule of heme
each heme contains 1 iron ion
pg 657
Blood types - surface antigens and plasma antibodies of each type
A:antigen A, Anti-B antibodies
B: antigen B, Anti-A antibodies
AB: Antigen A and B, no antibodies
O: Neither Antigen A or B, Anti-A and Anti-B antibodies
pg 663
What are the two steps of focusing?
We focus images on the retina by changing the shape of the lens to keep focal length constant. (accomodation)
Crystallins are responsible for the focusing power of the lens.

1. Light rays from a source are refracted when they reach the lens of the eye.
2. The rays are then focused onto a single point
Look at pg 575, fig 17-9.
Vibration of tympanic membrane converts sound waves into...
Mechanical movements
pg 587
Parts and steps involved in gustation...(taste)
Taste Receptors/Taste buds- Montitored by:
Facial nerve VII- on anterior 2/3 of tongue. Glossopharyngeal nerve IX- Posterior 1/3 of tongue including the circumvallate. Vagus Nerve X- scattered on surface of epiglottis. Then they synapse within the solitary nucleus of the medulla oblongata and then on to the thalamus and the primary sensory cortex.
pg 564
Parts and steps involved in olfaction...(smell)
When you inhale, the air swirls within your nasal cavity to the olfactory epehelium. When the axons leave it, 20 bundles penetrate the cribriform plate of the ethmoid to reach the olfactory bulbs or cerebrum (synapse). Then travel along the olf tract to the olf cortex, the hypothalamus and portions of the limbic system.
Olf-only one that reaches the cortex directly!
pg 563
Parts and steps involved in photoreception...
It begins when a photon strikes the retinal portion of rhodopsin molecule.
Step 1- Opsin is activated.
Step 2- Opsin Activates Transduin, which in turn activates phosphodiesterase
Step 3- Cyclic-GMP levels decline and gated sodium channels close.
Step 4- The dark current is reduced and the rate of neurotransmitter relase declines.
Pg 581
Parts and steps involved in balance...
balance: Equilibrium sensations are provided by receptors of the vestibular complex - hair cells, which provide information about the direction and strength of mechanical stimuli.• The vestibular receptors activate sensory neurons of the vestibular ganglia. The axons form the vestibular branch of the vestibulocochlear nerve (VIII), synapsing within the vestibular nuclei. • The reflexive motor commands issued by the vestibular nuclei are distributed to the motor nuclei for cranial nerves involved with eye, head, and neck movements
pg 589
balance:look at last paragraph-numbers1-4
Parts and steps involved in hearing...
The receptors of the cochlear duct provide a sense of hearing that enables us to detect the quietest whisper, yet remain functional in a noisy room.

•Step 1: Sound waves arrive at the tympanic membrane. The orientation of the canal provides some directional sensitivity.

• Step 2: Movement of the tympanic membrane causes displacement of the auditory ossicles. When the tympanic membrane vibrates, so do the malleus and, through their articulations, the incus and stapes. In this way, sound is amplified.
Step 3: Movement of the stapes at the oval window establishes pressure waves in the perilymph of the vestibular duct.
•Step 4: The pressure waves distort the basilar membrane on their way to the round window of the tympanic duct. The location of maximum distortion varies with the frequency of the sound. Information about frequency is translated into information about position along the basilar membrane.
•Step 5: Vibration of the basilar membrane causes vibration of hair cells against the tectorial membrane. This movement leads to the displacement of the stereocilia, which in turn opens ion channels in the hair cell membranes. The resulting inrush of ions depolarizes the hair cells, leading to the release of neurotransmitters and thus to the stimulation of sensory neurons. The number of hair cells responding in a given region of the organ of Corti provides information on the intensity of the sound.
•Step 6: Information about the region and intensity of stimulation is relayed to the CNS over the cochlear branch of the vestibulocochlear nerve (VIII). The sensory neurons are located in the spiral ganglion of the cochlea. From there, the information is carried by the cochlear branch of cranial nerve VIII to the cochlear nuclei of the medulla oblongata for subsequent distribution to other centers in the brain.
Figure 17-30
Pg 596
Characteristics and functions of: hair cells
They are the basic receptors of the inner ear,which provide information about the direction and strength of mechanical stimuli.
Hair cells do not actively move their kinocilium or stereocilia; instead external forces push these processes and distort the cell membrane.
pg 589
Function of inner ear
contains receptors in the saccule and utricle that provide sensations of gravity and linear acceleration.
pg 588
Function of middle ear
It communicates with the nasopharynx via the auditory (pharyngotympanic) tube.
•Vibration of the tympanic membrane converts arriving sound waves into mechanical movements.
pg 586
Passage of blood through the heart
Superior and inferior vena cava carry oxygen poor blood to the right atrium.
Right atrium sends blood through the atriventricular or tricuspid valve to the right ventricle.
Right ventricle sends blood through the pulmonary semilunar valve into the pulmonary trunk that divide into the pulmonary arteries to carry blood to the lungs.
Four pulmonary veins carry oxygen rich blood to the left atrium.
Left atrium sends blood through the atrioventricular valve or bicuspid valve to the left ventricle.
Left ventricle sends blood through the aortic semilunar valve into the aorta and out to the body.
slides
Definition of pulmonary curcuit
blood vessels between the pulmonary semilunar valve of the right ventricle and the entrance to the left atrium; the blood flow through the lungs.
dictionary
Definition of conducting system
network of specialized cardiac muscle cells that initiates and distributes electrical impulses.
pg 969
Defintion of Systole
contraction; the chamber contracts and pushes blood into the adjacent chamber or into an arterial trunk.
pg 703
definition of diastole
relaxation; during it, the chamber fills with blood and prepares for the next cadiac cycle.
pg 703
Cardiac muscles have a long refractory period so...
so rapid stimulation produces twitches rather thantetanic contractions.
long refractory period prevents summation and tetany
slides
Path of conducting system...
SA node-> Internodal pathways-> AV node-> av bundle -> bundle branches->purkinje fibers
pg 696
The basic heart rate is established by….. but can be modified by……
pacemaker cells in the av node; autonomic nervous system/hormones
greg notes
Cardiac output is affected by several factors, what are they
heart rate or stoke volume.
look at fig 20-20. pg 708
Know characteristics of: 3 layers of heart wall
epicardium: visceral pericardium that covers the outer surface of the heart.
myocardium:muscular wall of the heart, forms both atria and ventricles; contains blood vessels, nerves and muscle tissue.
endocardium: simple squamous epethelium that is continuous with the endothelium of the attached great vessels. Cover the inner surfaces of heart.
pg 684
connective tissues of the heart
includes large numbers of collagesn and elastic fibers. It provides physocal support for the cardiac muscle fibers, elp distribute forrces of contraction, add strength and prevent overexpansion of heart, porvide elasticity..
pg 692
cardiac cycle phases
1 atrial systole begins.
2. atrial systole ends; atrial diastole begins.
3. ventricular systole-first phase
4. ventricular systole-2nd phase
5. ventricular diastole-early
6. ventricular diastole-late
look at pg 704 fig 20-16
All chemical and gaseous exchange……
between the blood and interstitial fluid takes place across the capillary walls
michaela notes
Arteries carry blood where
away from the heart towards capillaries
pg 720
Veins carry blood where
towards the heart
pg 720
differences between veins and arteries
1. arteries dont have valves, veins do
2. arteries contrict, veins barely do.
3. artery walls are thicker than veins
4. arteies are smaller in diameter.
5 arteries retain their shape, veins colapse.
pg 721
Which system is a high pressure system
arteries
notes
When net filtration pressure is positive what happens?
fluid moves into the interstitial fluid - filtration
pg 736
When net filtration pressure is negative what happens?
fluid moves out of the interstitial fluid an into capillaries
pg 736
Homeostatic mechanisms regulate cardiovascular activity so that…..
to ensure that the tissue perfusion, or blood flow through the tissues, meets the demand fo oxygen and nutrients
pg 737
What three organs have special circulation?
brain, heart and lungs
pg 747
Explain how the body returns to homeostasis when blood pressure is too high or too low?
The baroreceptors respone
pg 740 fig 21-14
Define: vasoconstriction
a reduction in the diameter of the arterioles due to the contraction of smooth muscles in the tunica media
dictionary
define vasodilation
an increase in the diameter of the arterioles due to the relaxation of smooth muscles in the tunica media.
dictionary
Characteristics of: compensated stage
stage1- homeostatic adjustments can cope with the situation; blood flow is reduced but within tolerable limits.
notes
Characteristics of: progressive stage
stage2- blood flow declined by 25% or more, homeostatic mechanisms cannot cope, blood pressure low, venus return is reduced cardiac output is inadequate.
notes
Characteristics of: irreversible stage
stage 3- conditions in the heart, liver, kidneys, and CNS are deteriorating, death will occur even with medical treatment
notes
age-related changes in - blood
decreased hematocrit, constriction or blockage of peripheral veins, pooling of blood in the veins of the legs because valves dont work
pg 770
age-related changes in - heart
reduction in maximum cardiac output, changes in actiities of nodal and conducting cells, reduction in elasticity of cardiac skeleton, progressive atheroclerosis, replacement of damaged cardiac muscle cells by scar tissue
pg 770
age-related changes in - blood vessels
the inelastic walls of arteries become less tolerant of sudden pressure increases, which can lead to an aneurism; calcium salts can be deposited on weakened vascular walls, thrombi can form at atherolsclerosis plaques.
pg 770
Three functions of the lymphatic system
1. production , maintenence and distribution of lymphocytes that provide defense against infection
2. helps maintain blood volume
3. helps elmiminate local variations in the composition of interstitial fluid.
pg 777
Three goals of inflammation
1. Temporary repair and barrier against pathogens
2. Retards spread of pathogens into surrounding areas
3. Mobilization of local and systemic defenses:
and facilitation of repairs (regeneration)
slides
Four properties of immunity
Specificity; Versatility; Memory; Tolerance
slides
Antibody structure - what kind of chains
2 parallel pairs of polypeptide chains
1 pair of heavy chains and 1 pair of light chains
slides
Antibody structure - what kind of segments
Each chain contains: constant segments and variable segments
slides
T cell activation (who does what, and in what order);
fig 22-19
pg 804
B cell sensitization and activation (who does what, and in what order)
fig 22-20
pg 805
Function of: lymph nodes
A filter: purifies lymph before return to venous circulation
Removes: debris; pathogens; 99% of antigens
slides
function of interleukins
assist in the coordination of cell-mediated nd antibody-mediated immunities
dictionary
function of interferons
Proteins (cytokines) released by activated lymphocytes and macrophages
Trigger production of antiviral proteins in normal cells
Antiviral proteins do not kill viruses, block replication in cell
slides
define nonspecific defense
Always work the same way
Against any type of invading agent
slide
define specific defense
Protect against specific pathogens
Depend on activities of lymphocytes
Specific resistance (immunity):
develops after exposure to environmental hazards
slide
define cell-mediated immunity
involves close physical contact between activated Tc cells and foreign, abnormal or infected cells
slide
define antibody-mediated immunity
involves the production of specific antibodies by plasma cells derived from activated B cells
slide
Functions of: respiratory system
1. provide an extensive surface area for gas exchange b/w air and circulating blood
2. moving air to and from the exchange surfaces of the lungs along the respiratory tract
3. protect respiratory surfaces from dehydration
4. producing sounds involved in speaking
5. facilitating the detection of olfactory stimuli
pg 826
function of hemoglobin
Gas Pickup and Delivery
oxygen transport
slides
nose and nasal cavity do what to incoming air?
Warm and humidify inhaled air for arrival at lower respiratory organ
slides
What happens during swallowing (what does the body do to prevent food going into the trachea?)
the larynx is elevated and the epiglottis folds back over the glottis, preventing entry of food into the trachea.
slide
Passage of air through the respiratory system
external nares -nasal cavity  pharynx- larynx -trachea -primary bronchi - secondary bronchi- tertiary bronchi -bronchiole - terminal bronchiole - respiratory bronchiole -alveolar ducts- alveolar sacs ->alveoli
slides
Three steps of external respiration
1. pulmonary ventilation-breathing
2.gas diffusion across membranes and capillaries
3. transport of oxygen and carbon dioxide between alvolar capillariesand capillary beds in other tissues
notes
One step of internal respiration
exhange of dissolved gases between the blood and the intertitial fluid.
slide
When thoracic cavity volume increases….
the pressure inside the lungs is lowered and air enters the lungs
slide
When thoracic cavity volume decreases….;
the pressure inside the lungs increases and air is forced out of the lungs
slide
Five reasons why gas exchange at respiratory membrane is efficient
1. distances involves in gas exchange are small
2. the total surface area is large
3. the gases are lipids
4. the difference in partial pressure across the respiratory membrane are substantial
5. membranes dont pose a barrier to the movement of o2 and co2
pg 841
Homeostatic mechanisms involve……
autoregulation, neural mechanisms, and endocrine mechanisms
notes
definition of internal respiration
the diffusion of gases between interstitial fluid and cytoplasm
dictionary
definition of external respiration
the diffusion of gases between the alveolar air and the alveolar capillaries and between the systematic capillaries and peripheral tissues
dictionary
Two things required by metabolic reactions
oxygena and organic molecules
notes
The digestive tract consists of?
oral cavity, pharynx, esophagus, stomach, small intestine nad large intestine
notes
Four types of teeth – what they do;
incisors- clipping and cutting
cuspids-(canines) tearing and slashing
bicuspids(premolars)- crushing mashing and grinding
molars- used for crushing and grinding
notes
characteristics of three gastric phases;
cephalic- prepares the stomach to recieve the material. see, smell, tast, think about food.
gastric- arrival of food to stomach. has three machanisms-neural response, hormonal and local. may last several hours
intestinal phase- controls the rate of gastric emptying. neural and hormonal response.
pg 895
Where does most of the absorption occur
small intestine
notes
Large intestine reabsorbs what?
water, bile salts, vitamins, organic wastes, urobilinogen, and toxins
pg 913
Digestive system breaks down the physical structure…
of food
duhhh
define peristalsis
a wave of smooth muscle contractions that propel material along the axis of a tube such as the digestive tract
dictionary
Functions of: saliva
Lubricating the mouth
Moistening and lubricating materials in the mouth
Dissolving chemicals that:
stimulate taste buds; provide sensory information
4. Initiate digestion of:
complex carbohydrates by enzyme salivary amylase (ptyalin or alpha-amylase)
lipids by enzyme lingual lipase
slides
function of stomach pH of 1.5-2.0
kills most of microorganisms ingested with foods, denatures proteins, break down plant cells walls, necesarry for activatton and function of pepsin
notes
Cells need…..;
energy
notes
A lot of energy is released as……;
heat
notes
Energy yield of - glycolysis
2 ATP
fig 25-6
pg 939
energy yeild of TCA
2 ATP
pg 940
energy yeild of ETS
28 ETS
pg 940
Which lipoprotein is good cholesterol?;
HDL
notes
Which lipoprotein is bad cholesterol?
LDL
notes
Three factors why protein catabolism is an impractical source of for quick energy
1. proteins are more difficult to break apart than are complex carbohydrates or lipids
2. one of the by-products, ammonium ions, is toxic to cells
3. proteins form the most important structural and functional components of any cell.
notes
Mechanisms to increase heat loss
increased perspiration, increased respiration, peripheral vasodilation
notes
mechanisms to promote heat gain
decreased blood flow to dermis, shivering thermogenesis, nonshivering thermogenesis.
notes
definition of: catabolism
the breakdown of complex oraganic molecules into simpler components, accompanied by the release of energy.
dictionary
definition of: anabolism
the synthess of complex organic compounds from simpler precursors
dictionary
Matching on: five metabolic components and their characteristics
liver, adipose tissue, skeletal muscle, neural tissue and peripheral tissue
notes. more to it
definition and characteristics of: absorptive state
Is the period following a meal:
when nutrient absorption is under way
slide
definition and characteristics of: postabsorptive state
Is the period when nutrient absorption is not under way
Body relies on internal energy reserves for energy demands
slide
Can you recognize a picture of the following metabolic pathways: glycolysis
figure 25-3
pg 933
Can you recognize a picture of the following metabolic pathways: krebs cycle
figuure 25-4
pg 935
Can you recognize a picture of the following metabolic pathways: ETS
figure 25-5
pg 937
functions of the urinary system
excretion, elimination and homeostatic regulation, regulate blood volume and blood pressure, regulate plasma concentrations, help stabilize blood Ph, conserve valuable nutrients
notes
fx: countercurrent multiplication
exchange that occurs between thin descending loop and thick ascending loop, exchange of fluids in opposite direction,
notes
definition and function of: kidney
A component of the uriniary system,an organ functioning in the regulation of plasma composition including excretion of wastes and maintenance of normal fluid and electrolyte balances
detoxifies poisons.
definition
What the nephrons are responsible for?;
functional unit of the kidney. site where urine production begins
slide
Goal of urine production
: is to maintain homeostasis
by regulating volume and composition of blood
including excretion of metabolic waste produc
slide
energy yeild of TCA
2 ATP
pg 940
energy yeild of ETS
28 ETS
pg 940
Which lipoprotein is good cholesterol?;
HDL
notes
Which lipoprotein is bad cholesterol?
LDL
notes
Three factors why protein catabolism is an impractical source of for quick energy
1. proteins are more difficult to break apart than are complex carbohydrates or lipids
2. one of the by-products, ammonium ions, is toxic to cells
3. proteins form the most important structural and functional components of any cell.
notes
Mechanisms to increase heat loss
increased perspiration, increased respiration, peripheral vasodilation
notes
mechanisms to promote heat gain
decreased blood flow to dermis, shivering thermogenesis, nonshivering thermogenesis.
notes
definition of: catabolism
the breakdown of complex oraganic molecules into simpler components, accompanied by the release of energy.
dictionary
definition of: anabolism
the synthess of complex organic compounds from simpler precursors
dictionary
Matching on: five metabolic components and their characteristics
liver, adipose tissue, skeletal muscle, neural tissue and peripheral tissue
notes. more to it
Know: Maintaining the normal fluid balance involves
regultating the content and distribution of body water in the ECF and the ICF
notes
Four basic principles of fluid and electrolyte regulation;
look up in notes
too much to type
Two reasons why electrolyte balance is important
total electrolyte concentrations diectly affect water balance,
the concentration of individual electrolytes can effect cell function
notes
Define: fluid balance
when the amount of water you gain each day is equal to the amount you lose in the enviroment.
notes
Summary of Renal Function p. 980-982
look it up
pg 980
Concentration of the components of the urine depends on what?;
the osmotic movement of water across the walls of the tubules and collecting ducts
notes
Urine volume and osmolarity are regulated…;
through the control of water reabsorption
notes
Five functions of PCT;
reabsorption of organic nutrients, active reabsoption of ions, reabsoprtion of water, passive reabsorption of ions, and secretion
notes
Four reasons why the renal corpuscle is….;
1. its membranes are designed for filtration, contains highly coiled capillaries, efferent arterioles are smaller in diameter than afferent
notes
Goal of autoregulation at the local level and how it accomplishes that goal;
to cause immediate localized homeostatic adjustments.
notes
define electrolyte balance
Balances gains and losses of all electrolytes
Primarily involves balancing rates of absorption across digestive tract with rates of loss at kidneys and sweat glands
slide
define acid-base balance
Precisely balances production and loss of hydrogen ions (pH)
The body generates acids during normal metabolism:
tends to reduce pH
slide
define fluid shift
Are rapid water movements between ECF and ICF:
in response to an osmotic gradient
slide
define buffer system
interacting compounds that prevent increases or decreases in the Ph of body fluids
dictionary
define acidosis
an abnormal physiological state characterized by plasma ph below 7.35
dictionary
define alkalosis
the condidtion characterized by a plasma ph greater than 7.45
dictionary
define fertilization
the fusion of a secondary oocyte and a spermatozoon to form a zygote
dictionary
define accessory glands
secrete fluids into ducts
slide
function of: reproductive system
producing storing, nourishing and transporting functional male and female reproductive cells
pg 1042
fx: testosterone
released in response to LH, most important androgen

stimulates spermatogenesis, affect CNS function, stimulate metabolism, establish and maintainmale secondary sex characteristics.
pg 1057
fx:female reproductive system
Female reproductive system: produce sex hormones, functional gametes

and develop/support/protect an embryo and nourishes newborn infant.



Principal organs of the female reproductive system include the

ovaries, uterine tubes, uterus, vagina, and external genitalia.
notes
fx: estrogen
Stimulating bone and muscle growth

• Maintaining female secondary sex characteristics such as

body hair and adipose tissue distribution

• Affects CNS activity (increases sexual drive)

• Maintaining functional accessory reproductive glands and

organs

• Initiating repair and growth of the endometrium

High levels of estrogen stimulate LH secretion, increase pituitary

sensitivity to GnRH and increase the GnRH pulse frequency.

Surge in LH concentration triggers:

• Completion of meiosis I by the primary oocyte

• Rupture of the follicular wall

• Ovulation
notes
Differences b/ween mitosis and meiosis
1. meiosis two divisions to produce four cells

mitosis has 1 division to produce two cells

2. meiosis produces haploid cells – cells that contain only one

pair of chromosomes

mitosis produces diploid cells – cells that contain both pairs of

chromosomes

3. In meiosis DNA replication only occurs once

4. Meiosis allows for genetic variation

Mitosis produces cells with an exact copy of the original DNA
notes
Steps in ovarian cycle
The ovarian cycle is divided into a follicular (preovulatory) phase

and a luteal (posovulatory) phase.

Steps:

1. Formation of primary follicles

2. Formation of secondary follicles

3. Formation of a tertiary follicle

4. Ovulation - a secondary oocyte and the surrounding

follicular cells of the corona radiata are released through

the ruptured ovarian wall

5. Formation and degeneration of the corpus luteum

The follicular cells remaining within the ovary form the corpus

luteum, which later degenerates into a corpus albicans of

scar tissue.
notes
characteristics of the 3 phases of the uterine cycle
Three phases: menses, proliferative phase, secretory phase

Menses – degeneration of the functional zone

Menstruation – endometrial sloughing, usually lasts 1 to 7

days

Dysmenorhea – painful menstruation

Proliferative phase - the functional zone undergoes repair and

thickens.

Secretory phase – endometrial glands enlarge and accelerate

their rates of secretion

Menstrual activity begins at menarche (- first menstrual period)

and continues until menopause (- last menstrual period)
notes
definition of: development
Time refuses to stand still; today’s infant will be tomorrow’s adult. The gradual modification of anatomical structures and physiological characteristics during the period from fertilization to maturity is called development
notes
define differentation
the gradual apperance of characteristic cellular specializations during development as the result of gene activation or repression
dictionary
define genetics
the study of mechanisms of hereditary
dictionary
What is going on during each trimester?
The first trimester is the period of embryological and early fetal development. During this period, the rudiments of all the major organ systems appear.
2. The second trimester is dominated by the development of organs and organ systems, a process that nears completion by the end of the sixth month. During this period, body shape and proportions change; by the end of this trimester, the fetus looks distinctively human.
3. The third trimester is characterized by rapid fetal growth and deposition of adipose tissue. Early in the third trimester, most of the fetus’s major organ systems become fully functional. An infant born one month or even two months prematurely has a reasonable chance of survival.
pg 1078
What changes occur in maternal systems during pregnancy?
Maternal Respiratory Rate Goes Up and Tidal Volume Increases
Maternal Blood Volume Increases
Maternal Requirements for Nutrients Climb 10–30 Percent
pg 1091
What is going on during each stage of labor
dilation
expulsion
placental
look up!
look them up
Know the definition and characteristics of: dominant
Dominant allele expressed in phenotype, regardless of conflicting instructions carried by other allele
slide
Know the definition and characteristics of: recessive,
Expressed in phenotype only if same allele is present on both chromosomes of homologous pair
slide
Know the definition and characteristics of: incomplete dominance
Heterozygous alleles produce unique phenotype
slide
Know the definition and characteristics of: codominance
Exhibits both dominant and recessive phenotypes for trait
slide
Know the definition and characteristics of: sex-linked inheritance.
The X chromosome also carries genes that affect somatic structures. These characteristics are called X-linked (or sex- linked), because in most cases there are no corresponding alleles on the Y chromosome
slide