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17 Cards in this Set
- Front
- Back
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Intermediate mesoderm structures (2)
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Adrenal cortex
Nephrogenic cord |
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Nephrogenic cord structures (4)
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Mesonephric duct
Paramesonephric duct Metanephrongenic tissue Gonadal ridge |
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Mesonephric duct
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Ureteric bud
Becomes ductus deferens in the male |
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Paramesonephric duct
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Becomes uterine tube, uterus and vagina
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Metanephrogenic tisue
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Forms nephrons of kidneys
Connects with uteric bud to form rest of kidney |
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Gonadal ridge
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Tissues of gonads
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Urogenital sinus
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Anterior part of hindgut (separated by septum)
Becomes bladder Female urethra Prostatic and membraneous parts of male urethra |
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Genital tubercle
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Glans of penis and clitoris
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Urethral folds
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Labia minora and vestibule
Or they close to form body of penis and urethra |
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Labioscrotal folds
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Scrotum
Labia majora |
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Three levels of sex determination
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Chromosomal
Gonadal Phenotypic |
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Disorders of testicular differentiation
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Female phenotype and streak gonads
Or ambiguous external genitalia (if only part of disorder) |
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MIF deficiency
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Normal testes and differentiation
Have uterus and fallopian tubes |
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Testosterone synthesis deficiency
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Synthesized from cholesterol
Can have ambiguous external genitalia Gynecomastia at puberty |
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Androgen receptor defects
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Complete testicular feminization
Phenotypic females with testes Diagnosed at puberty when no menses |
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Enzyme deficiencies in testosterone metabolism
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In the Dominica Republic
Ambiguous external genitalia until puberty (then male) |
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Normal male development (5 steps)
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Sry gene produced by testis
Mullerian inhibiting factor produced Dihydrotestosterone masculizes genitalia Testosterone masculinizes male ducts in utero |
