Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
159 Cards in this Set
- Front
- Back
True or false: Mesoderm gives rise to muscle, bone, and blood.
|
true
|
|
True or false: Columnar cells lining the small intestine show a brush border of microvilli on the apical surface.
|
true
|
|
True or false: Nonkeratinized cells exfoliate from the surface of the skin.
|
false
|
|
True or false: In an epithelium, there is almost no extracellular matrix.
|
true
|
|
True or false: The clear gel that usually surrounds cells is called interstitial fluid.
|
true
|
|
True or false: Fibrocartilage is found in intervertebral discs.
|
true
|
|
True or false: Blood consists of cells and a ground substance made of formed elements.
|
false
|
|
True or false: Plasma cells produce the ground substance that forms the matrix of connective tissues.
|
false
|
|
True or false: Excitable cells respond to outside stimuli by means of changes in plasma membrane shape.
|
false
|
|
True or false: Smooth and cardiac muscles are under involuntary control.
|
true
|
|
True or false: Dendrites in a neuron send outgoing signals to other cells.
|
false
|
|
True or false: Desmosomes are more effective than tight junctions in preventing substances from passing between cells.
|
false
|
|
True or false; The duct of an endocrine gland leads into the bloodstream rather than onto an epithelial surface.
|
false
|
|
True or false: The secretory product of a gland is produced by its parenchyma, not its stroma.
|
true
|
|
True or false: Scar tissue helps to hold an organ together but does not restore normal function of the damaged tissue.
|
true
|
|
There are 50 trillion cells of ______ different cell types.
|
200
|
|
List the four broad categories of tissues.
|
epithelial tissue
connective tissue nervous tissue muscular tissue |
|
What is a structure with discrete boundaries that is composed of two or more tissue types?
|
organ
|
|
What is a group of similar cells and cell products that arise from the same region of the embryo and work together to perform a specific structural or physiological role in an organ?
|
tissue
|
|
In what ways do the four primary tissues differ from one another?
|
types and functions of their cells
characteristics of the matrix (extracellular material) relative amount of space occupied by cells versus matrix |
|
What is the matrix (extracellular material) composed of?
|
fibrous proteins
clear gel called ground substance, tissue fluid, extracellular fluid (ECF), interstitial fluid, or tissue gel |
|
In what form does human development begin?
|
single cell -- fertilized egg
divides to produce scores of identical, smaller cells first tissues appear when these cells start to organize themselves into layers: first two, then three strata |
|
What are the 3 primary germ layers?
|
Ectoderm (outer) --> gives rise to epidermis and nervous system
Endoderm (inner) --> gives rise to mucous membrane lining, digestive and respiratory tracts, digestive glands, etc. Mesoderm (middle) --> becomes gelatinous tissue called mesenchyme; wispy collagen fibers and fibroblasts in gel matrix; gives rise to muscle, bone, blood. |
|
Describe the ectoderm germ layer.
|
(outer) gives rise to epidermis and nervous system
|
|
Describe the endoderm germ layer.
|
(inner) gives rise to mucous membrane, digestive and respiratory tracts, digestive glands, etc.
|
|
Describe the mesoderm germ layer.
|
(middle) becomes gelatinous tissue called mesenchyme
wispy collagen fibers and fibroblasts in the gel matrix gives rise to muscle, bone, blood |
|
Which tissue section consists of tissue sliced into thin sections one or two cells thick?
|
histological sections
|
|
Which tissue section consists of tissue mounted on slides and artificially colored with histological stain?
|
stains
|
|
Sectioning reduces 3-dimensional structure to ___________________.
|
2-dimensional slice
|
|
Which tissue section consists of tissue cut along long direction of organ?
|
longitudinal section (l.s.)
|
|
Which tissue section consists of tissue cut perpendicular to length of organ?
|
cross section (c.s. or x.s.) or transverse section (t.s.)
|
|
Which tissue section consists of tissue cut at angle between cross and longitudinal sections?
|
oblique section
|
|
Which tissue section consists of tissue rubbed or spread across slide? Give examples.
|
smear
spinal cord or blood |
|
Which tissue section consists of cobwebby tissue laid out on slide? Give examples.
|
spread
areolar tissue |
|
Which form of tissue consists of a flat sheet of closely adhering cells and is one or more cells thick?
|
epithelial tissue --> covers body surface and lines body cavities
upper surface is usually exposed to the environment or an internal space in the body forms the external and internal linings of many organs |
|
Which form of epithelial tissue contains 1 layer of cells and is named by the shape of cells?
|
simple epithelium --> all cells touch the basement membrane
|
|
Which form of epithelial tissue contains more than 1 layer of cells and is named by the shape of apical cells?
|
stratified epithelium --> some cells rest on top of others and do not touch basement membrane
|
|
Name and describe the 4 types of simple epithelia.
|
simple squamous (thin, scaly cells)
simple cuboidal (square or round cells) simple columnar (tall, narrow cells) pseudostratified columnar (shorter cells are covered by taller ones; all cells reach the basement membrane) |
|
What are wineglass-shaped mucus-secreting cells In simple columnar and pseudostratified epithelia?
|
goblet cells
|
|
Which form of simple epithelia permits rapid diffusion or transport of substances and secretes fluid?
|
simple squamous epithelium --> single row of thin cells
alveoli, glomeruli, endothelium, and serosa |
|
Which form of simple epithelia functions for absorption and secretion, mucus production, and movement?
|
simple cuboidal -> single layer of square or round cells
liver, thyroid, mammary and salivary glands, bronchioles, and kidney tubules |
|
Which form of simple epithelia contains a brush border of microvilli ciliated in some organs, may possess goblet cells, and functions for secretion and absorption as well as the secretion of mucus?
|
simple columnar epithelium --> single row of tall, narrow cells
oval nuclei in basal half of cell lining of GI tract, uterus, kidney, and uterine tubes |
|
Which form of simple epithelia contains nuclei at several layers, cilia and goblet cells, and secretes and propels mucus?
|
pseudostratified epithelium --> looks multilayered, some not reaching free surface; all touch basement membrane
respiratory tract and portions of male |
|
Which form of tissue consists of some cells resting directly on others allowing only the deepest layer to reach the basement membrane, and consists of 2-20 or more layers of cells?
|
stratified epithelia
Three stratified epithelia are named for the shapes of their surface cells. stratified squamous stratified cuboidal stratified columnar (rare) 4th type: transitional epithelium |
|
What is the most widespread epithelium in the body?
|
stratified epithelia
|
|
The deepest layers of stratified epithelia undergo continuous _____________. Explain.
|
mitosis
Their daughter cells push toward the surface and become flatter as they migrate farther upward. finally die and flake off through exfoliation or desquamation |
|
Describe the two kinds of stratified squamous epithelia.
|
keratinized --> found on surface of skin, abrasion resistant
nonkeratinized --> lacks surface layer of dead cells |
|
Which form of stratified epithelia resists abrasion, retards water loss through skin, and resists penetration by pathogenic organisms?
|
keratinized stratified squamous --> flat and scaly surface
epidermis; palms and soles heavily keratinized |
|
Which form of stratified epithelia resists abrasion and penetration of pathogens?
|
nonkeratinized stratified squamous
tongue, oral mucosa, esophagus, and vagina |
|
Which form of stratified epithelia secretes sweat and produces sperm and ovarian hormones?
|
stratified cuboidal epithelium --> surface cells square or round
sweat gland ducts, ovarian follicles, and seminiferous tubules |
|
Which form of stratified epithelia allows for filling of urinary tract?
|
transitional epithelium --> change from round to flat when stretched
ureter and bladder |
|
What is a type of tissue in which cells usually occupy less space than the extracellular material and binds organs to each other, and supports and protects organs?
|
connective tissue --> highly vascular (richly supplied with blood vessels)
most abundant, widely distributed, and histologically variable of the primary tissues Most cells of connective tissue are not in direct contact with each other (separated by extracellular material) |
|
What are the functions of connective tissue?
|
binding of organs such as tendons and ligaments
support bones and cartilage physical protection of the cranium, ribs, and sternum immune protections -- white blood cells attack foreign invaders movement -- bones provide lever system storage of fat, calcium, and phosphorus heat production -- metabolism of brown fat in infants transport blood |
|
What is another word for white blood cells?
|
leukocytes
neutrophils wander about attacking bacteria lymphocytes react against bacteria, toxins, and other foreign material |
|
Which form of fibrous connective tissue produce fibers and ground substance?
|
fibroblasts
|
|
Which form of fibrous connective tissue phagocytizes foreign material and activate the immune system when they sense foreign matter or antigens?
|
macrophages --> arise from white blood cells called monocytes
|
|
Which form of fibrous connective tissue synthesizes disease-fighting antibodies?
|
plasma cells --> arise form lymphocytes
|
|
Which form of fibrous connective tissue is found alongside blood vessels?
|
mast cells --> secrete heparin to inhibit clotting; secrete histamine to dilate blood vessels
|
|
Which form of fibrous connective tissue stores triglycerides or fat molecules?
|
adipocytes
|
|
Which fibers are tough, flexible, and resist stretching, are found in tendons, ligaments, and deep layer of the skin?
|
collagenous fibers --> most abundant of the body's proteins (25%)
|
|
Which fibers are thin collagen fibers coated with glycoprotein that form the framework of organs such as the spleen and lymph nodes?
|
reticular fibers
|
|
Which fibers are thinner than collagenous fibers, branch and rejoin each other, are made of protein called elastin, and allows stretching and recoiling?
|
elastic fibers
yellow fibers - fresh elastic fibers |
|
What is a long polysaccharide composed of unusual disaccharides called amino sugars and uronic acid which plays an important role of regulating water and electrolyte balance in the tissues?
|
glycosaminoglycans (GAGs)
|
|
What is the most abundant GAG and what is its function?
|
chondroitin sulfate --> in blood vessels and bone
responsible for stiffness of cartilage |
|
Ground substance is usually a gelatinous to rubbery consistency resulting from three classes of large molecules. What are these 3 classes?
|
glycosaminoglycans (GAGs)
proteoglycans adhesive glycoproteins |
|
What is a gigantic molecule shaped like a test-tube brush that forms thick colloids which create strong structural bonds between cells and extracellular macromolecules?
|
proteoglycans --> holds tissues together
|
|
Which form of fibrous connective tissue is composed of loosely organized fibers, abundant blood vessels, and a lot of seemingly empty space?
|
areolar tissue
underlies all epithelia, in serous membranes, between muscles, passageways for nerves and blood vessels |
|
Nearly every epithelium rests on a layer of ____________ tissue.
|
areolar
|
|
Which form of fibrous connective tissue is composed of reticular fibers and fibroblasts and forms supportive stroma (framework) for lymphatic organs?
|
reticular tissue --> loose connective tissue
found in lymph nodes, spleen, thymus, and bone marrow |
|
Which form of fibrous connective tissue is composed of densely packed, parallel collagen fibers, and compressed fibroblast nuclei?
|
dense regular connective tissue
elastic tissue/fibers wavy sheets Tendons attach muscles to bones and ligaments hold bones together. |
|
Which form of fibrous connective tissue is composed of densely packed, randomly arranged, collagen fibers and few visible cells that withstands unpredictable stresses?
|
dense irregular connective tissue
deeper layer of skin; capsules around organs |
|
What is the body's primary energy reservoir?
|
fat
The quantity of stored triglycerides and the number of adipocytes are quite stable in a person. |
|
What is the space between adipocytes occupied by?
|
areolar tissue, reticular tissue, and blood capillaries
|
|
Which form of tissue provides thermal insulation, anchors and cushions organs such as eyeballs and kidneys, and contributes to body contours (female breast and hips)?
|
adipose tissue --> empty-looking cells with thin margins
On average, women have more fat than men. Too little can reduce female fertility. Most adult fat is called white fat. |
|
What is the heat-generating tissue found in hibernating animals, fetuses, infants, and children?
|
brown fat
|
|
What is the supportive connective tissue with flexible, rubbery matrix that gives shape to ear, tip of nose, and larynx?
|
cartilage
Chondroblasts produce matrix and surround themselves until they become trapped in little cavities (lacunae). |
|
What are the cartilage cells in lacunae?
|
chrondrocytes
|
|
What is the sheath of dense irregular connective tissue that surrounds elastic and most hyaline cartilage?
|
perichondrium --> surrounds elastic and most hyaline cartilage (NOT articular cartilage)
contains a reserve population of chondroblasts that contribute to cartilage growth throughout life |
|
Which process bring nutrients and removes wastes from cartilage?
|
diffusion (because it has no blood vessels)
Cartilage heals slowly. |
|
Which form of cartilage eases joint movement, hold airway open, moves vocal cords during speech, and has a clear, glassy microscopic appearance because of unusual fineness of the collagen fibers?
|
hyaline cartilage --> usually covered by perichondrium
articular cartilage, costal cartilage, trachea, larynx, fetal skeleton |
|
Which form of cartilage contains elastic fibers and provides flexible, elastic support to the external ear and epiglottis?
|
elastic cartilage --> covered with perichondrium
|
|
Which form of cartilage contains large, coarse bundles of collagen fibers, resists compression, and absorbs shock?
|
fibrocartilage --> never has perichondrium
pubic symphysis, menisci, and intervertebral discs |
|
What are the two meanings of bone?
|
an organ of the body
femur, mandible composed of multiple tissue types |
|
What makes up most of the mass of bone?
|
osseous tissue (bone tissue)
|
|
Which form of osseous tissue consists of delicate struts of bone called trabeculae and is found in heads of long bones and in middle of flat bones such as the stenum?
|
spongy bone --> covered by compact bone; spongy in appearance
|
|
Which form of osseous tissue is a dense, calcified tissue with no visible spaces in which the cells and matrix surround vertically oriented blood vessels in long bones?
|
compact bone --> more complex arrangement
|
|
What is the central canal of the bone and its surrounding lamellae?
|
osteon
|
|
Where is bone matrix deposited?
|
concentric lamella
|
|
Compact bone is arranged in cylinders that surround ___________________ that run longitudinally through shafts of long bones.
|
central (haversion or osteonic) canals
|
|
What are mature bone cells that occupy the lacunae?
|
osteocytes
|
|
What are delicate canals that radiate from each lacuna to its neighbors, and allow osteocytes to contact each other?
|
canalculi
|
|
What is tough fibrous connective tissue that covers the bone as a whole?
|
periosteum
|
|
Which form of connective tissue transports cells and dissolved matter from place to place?
|
fluid connective tissue
|
|
What is the term that describes blood's liquid ground substance?
|
plasma
|
|
What is another word for red blood cells?
|
erythrocytes --> transport O2 and CO2
|
|
What are the cell fragments involved in clotting and other mechanisms?
|
platelets
|
|
Excitability is a characteristic of all living cells. Which systems is this characteristic developed to the highest degree?
|
excitability
|
|
What is the electrical charge difference (voltage) that occurs across the plasma membranes and is the basis for their excitation?
|
membrane potential
|
|
How do nerves respond to changes in membrane potential?
|
rapid transmission of signal signals to other cells
|
|
How do muscles respond to changes in membrane potential?
|
contraction, shortening of the cell
|
|
Which part of the neuron houses nucleus and other organelles and is the cell's center of genetic control and protein synthesis?
|
neurosoma
|
|
Which part of the neuron consists of multiple short, branches processes that receive signals from other cells, and transmit messages to neurosoma?
|
dendrites
|
|
Which part of the neuron sends outgoing signals to other cells?
|
axon (nerve fiber) --> can be more than a meter long
|
|
Which form of tissue is specialized for communication by electrical and chemical signals?
|
nervous tissue --> consists of neurons (nerve cells) and neuroglia
|
|
Which cells in nervous tissue detect stimuli, respond quickly, and transmit coded information rapidly to other cells?
|
neurons (nerve cells)
|
|
Which cells in nervous tissue protect and assist neurons, and are considered "housekeepers" of the nervous system?
|
neuroglia (glial)
|
|
Which form of tissue consists of elongated cells that are specialized to contract in response to stimulation?
|
muscular tissue --> primary job is to exert physical force on other tissues and organs
creates movements involved in body and limb movement, digestion, waste elimination, breathing, speech, and blood circulation important source of body heat |
|
What are the 3 types of muscle?
|
skeletal
cardiac smooth |
|
Which form of muscular tissue is composed of long, threadlike cells called muscle fibers, contains striations, and is voluntary?
|
skeletal muscle --> striations, voluntary
most attach to bone containing multiple nuclei adjacent to plasma membrane |
|
Which form of muscular tissue is limited to the heart, is striated, and involuntary?
|
cardiac muscle --> striations, involuntary
myocytes or cardiocytes are shorter, branched, and notched at ends contain one centrally located nucleus surrounded by light-staining glycogen intercalated discs join cardiocytes end to end |
|
Which form of muscular tissue consists of one centrally located nucleus, relatively short fusiform cells, lacks striations, and is involuntary?
|
smooth muscle --> lacks striations, involuntary
visceral muscle - forms layers of digestive, respiratory, and urinary tract: propels contents through an organ, regulates diameter of blood vessels |
|
What are the connections between one cell and another?
|
cell junctions
All cells (except blood and metastatic cancer cells) are anchored to each other or their matrix by intercellular junctions resist stress and communicate with each other |
|
Which junction is a region in which adjacent cells are bound together by fusion of the outer phospholipid layer of their plasma membranes?
|
tight junction --> seals of intercellular space; makes it impossible for substance to pass between cells
in epithelia, forms a zone that completely encircles each cell near its apical pole |
|
What is a patch that holds cells together, serves to keep cells from pulling apart, and resists mechanical stress?
|
desmosomes (like a clothing snap)
hooklike J-shaped proteins arise from the cytoskeleton |
|
What anchors the basal cells of epithelium to the underlying basement membrane causing epithelium to not easily peel away from underlying tissues?
|
hemidesmosomes
|
|
Which junction is formed by a ringlike protein called connexon, consists of 6 transmembrane proteins arranged like segments of an orange, and has surrounding water-filled pores?
|
gap (communicating) junction
ions, glucose, amino acids, and other solutes pass from one cell to the next |
|
What is a cell or organ that secretes substances for use elsewhere in the body or releases them for elimination from the body?
|
gland --> composed of epithelial tissue in a connective tissue framework and capsule
may produce product synthesized by the gland (digestive enzymes) or products removed from tissues and modified by the gland (urine) secretion product is useful to the body excretion production is waste |
|
Which glands maintain their contact with the body surface by way of a duct (epithelial tube that conveys secretion to surface)?
|
exocrine glands
sweat, mammary, and tear glands |
|
Which glands lose their contact with the surface and have no ducts?
|
endocrine glands
hormones secrete (hormones) directly into blood thyroid, adrenal, and pituitary glands |
|
Which organs have both exocrine and endocrine glands?
|
liver, gonads, pancreas
|
|
Which glands are found in epithelium that is predominantly nonsecretory and can be endocrine or exocrine?
|
unicellular glands
mucus-secreting goblet or endocrine cells of stomach and small intestine |
|
What is the connective covering of most exocrine glands?
|
capsule
|
|
What are extensions of the capsule that divide the interior of the gland into compartments (lobes, which may be further divided into lobules)?
|
septa or trabeculae
|
|
What is the connective tissue framework of the exocrine gland that supports and organizes granular tissue?
|
stroma
|
|
What are cells that perform the tasks of synthesis and secretion in exocrine glands?
|
parenchyma --> typically cuboidal or simple columnar epithelia
|
|
Which glands produce thin, watery secretions?
|
serous glands
perspiration, milk, tears, digestive juices |
|
Which glands produces the glycoprotein, mucin, which absorbs water to form a sticky secretion called mucus?
|
mucous glands
goblet cells: unicellular mucous glands |
|
Which glands release whole cells, sperm, and egg cells?
|
cytogenic glands
|
|
What is the shape of an exocrine gland in which the duct and secretory portion have uniform diameter?
|
tubular
|
|
What is the shape of an exocrine gland that has secretory cells that form a dilated sac?
|
acinar
|
|
What is the shape of an exocrine gland that has both tubular and acinar portions?
|
tubloacinar
|
|
Which exocrine gland structure has an unbranched duct? branched duct?
|
simple - unbranched duct
compound - branched duct |
|
How do merocrine (eccrine) glands release their secretion?
|
vesicles release the secretion of merocrine glands by exocytosis
tear glands, pancreas, gastric glands, and others |
|
List examples of apocrine glands.
|
axillary sweat glands, mammary glands
|
|
Which gland cells accumulate a product and then the entire cell disintegrates and has a secretion mixture of cell fragments and synthesized substance?
|
holocrine glands
all glands of scalp, glands of eyelids |
|
Which membrane consists of stratified squamous epithelium resting on a layer of connective tissue and is considered the largest membrane in the body?
|
cutaneous membrane (skin)
stratified squamous epithelium (epidermis) resting on a layer of connective tissue (dermis) |
|
Which membrane lines passages that open to the external environment?
|
mucous membranes (mucosa)
absorptive, secretory, and protective functions |
|
Which membrane is the internal membrane that consists of simple squamous epithelium resting on a layer of areolar tissue?
|
serous membrane (serosa)
produces serous fluid that arises from blood covers organs and lines walls of body cavities |
|
How can damaged tissues be repaired?
|
regeneration --> replacement of dead or damaged cells by the same type of cell as before; restores normal function
skin injuries and liver regenerate fibrosis --> replacement of damaged cells with scar tissue; holds organs together, does not restore normal function severe cuts and burns, healing of muscle injuries, scarring of lungs in tuberculosis |
|
What is the term that describes tissue growth through cell multiplication?
|
hyperplasia
|
|
What is the term that describes the enlargement of preexisting cells?
|
hypertrophy
|
|
Which membrane lines joint cavities?
|
synovial membrane
connective tissue layer only, secretes synovial fluid |
|
What is the term that describes the development of a tumor (pleoplasm)?
|
neoplasia
benign or malignant composed of abnormal, nonfunctional tissue |
|
What are undifferentiated cells that are not yet performing any specialized function but have potential to differentiate?
|
stem cells
|
|
What is the term that describes the process in which unspecialized tissues of embryo become specialized mature types?
|
differentiation
ex: mesenchyme to muscle |
|
What is the term that describes the process of changing from one type of mature tissue to another?
|
metaplasia
simple cuboidal tissue of vagina before puberty changes to stratified squamous after puberty pseudostratified columnar epithelium of bronchi of smokers to stratified squamous epithelium |
|
Describe totipotent embryonic stem cells.
|
have potential to develop into any type of fully differentiated human cells
source: cells of very early embryo |
|
Describe pluripotent embryonic stem cells.
|
can develop into any type of cell in the embryo
source: cells of inner cell mass of embryo |
|
Describe multipotent adult stem cells.
|
bone marrow producing several blood cell types
|
|
Describe unipotent adult stem cells.
|
most limited plasticity; only epidermal cells produced
|
|
Describe the healing of a cut into the skin.
|
severed blood vessels bleed into the cut
mast cells and damaged cells release histamine dilates blood vessels increases blood flow to area makes capillaries more permeable |
|
What 3 things does blood plasma that seeps into a wound carry?
|
antibodies
clotting proteins blood cells |
|
What forms the scab that temporarily wounds and blocks infection?
|
blood clot
macrophages phagocytize and digest tissue debris |
|
What is the shrinkage of a tissue through a loss in cell size or number?
|
atrophy
sterile atrophy --> through normal aging disuse atrophy --> from lack of use |
|
What is the premature, pathological death of tissue due to trauma, toxins, or infections?
|
necrosis
|
|
Which form of necrosis occurs when blood supply is cut?
|
infarction
|
|
Which form of necrosis occurs when due to insufficient blood supply?
|
gangrene
|
|
Which form of necrosis occurs due to a bed sore or pressure sore?
|
decubitis ulcer
|
|
Which form of necrosis occurs due to an anaerobic bacterial infection?
|
gas gangrene
|