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102 Cards in this Set

  • Front
  • Back
What is anatomy?
the study of form
What are the four ways in which the structure of the human body may be examined?
inspection (eyes)

palpation (fingers)

auscultation (listening)

percussion (tapping)
What is the term that describes the cutting and separation of tissues to reveal their relationships?
Cadaver dissection
What is the term that describes the study of more than one species in order to examine structural similarities and differences, and analyze evolutionary trends?
comparative anatomy
Explain and describe the seven ways to study anatomy.
exploratory surgery - open the body and look inside

medical imaging - (non-invasive) viewing the inside of the body WITHOUT surgery; radiology - branch of medicine concerned with imaging

gross anatomy - study of structures that can be seen with the naked eye

cytology - study of structure and function of cells

histology - (microscopic anatomy) examination of cells with a microscope

ultrastructure - view molecular detail under electron microscope

histopathology - microscopic examination of tissues for signs of disease
What is physiology?
the study of function
List and describe the three subdisciplines of physiology.
neurophysiology - physiology of nervous system

endocrinology - physiology of hormones

pathophysiology - mechanisms of disease
What puts a limitation of human experimentation and is the basis for the development of new drugs and medical procedures (via animal surgery and animal drug tests)?
comparative physiology
What did physicians in Mesopotamia and Egypt use 3,000 years ago?
herbal drugs, salts, and physical therapy
Which scientist was named "Father of medicine" and established the code of ethics?
Hippocrates --> established a code of ethics (Hippocratic oath)

urged physicians to seek natural causes of disease rather than attributing them to acts of the gods and demons
Which physician was one of the first philosophers to write about anatomy and physiology and believed that diseases had either supernatural causes or physical causes?
Aristotle --> believed that complex structures are built from simpler parts

called supernatural causes of disease = theologi
called natural causes for disease = physiologi
This gave rise to the terms physician and physiology.
What two terms did Aristotle coin?
theologi = supernatural causes of diseases

physiologi = natural causes for diseases
What physician was one to the Roman gladiators and saw science as a method of discover, not just a body of facts taken on faith?
Cladius Galen --> wrote book advising followers to trust their own observation more than the teaching of dogma of the "ancient masters"

did animal dissections since use of cadavers was banned during his time
What Jewish physician wrote 10 influential medical texts and was a physician to Egyptian sultan, Saladin?
Maimonides (Moses ben Maimon)
Which Muslim physician was known as "The Galen of Islam" and wrote "The Canon of Medicine" used in medical schools for 500 years?
Avicenna (Ibn Sina) --> combined Galen and Aristotle findings with original discoveries
Which physiologist's contributions represent the birth of experimental physiology and realized blood flows out from the heart and back to it again?
William Harvey --> published book De Motu Cordis (On the Motion of the Heart) in 1628
Who were the first Western scientists to realize that blood must circulate continuously around the body, from the heart to other organs, and back to the heart again?
William Harvey and Michael Servetus
Which scientist taught anatomy in Italy and published the first atlas of anatomy called De Humani Corporus Fabrica (On the Structure of the Human Body)?
Andreas Vesalius
What scientist made many improvements to the compound microscope? What changes were made?
Robert Hooke --> ocular lens (eyepiece) and objective lens (near specimen)

invented specimen stage, illuminator, and fine focus controls

his microscopes magnified 30x

first to see and name cells

first comprehensive book of microscopy
What scientist invented a simple (single-lens) microscope with great magnification to look at fabrics (200x)?
Antony van Leeuwenhoek

published his observations of blood, lake water, sperm, bacteria from tooth scrapings, and many other things
What is the term used to describe the branch of medicine concerned with imaging?
radiology (medical imaging)
What are the benefits of a large sample size?
controls for chance events and individual variation

enables us to place greater confidence in the outcome
What are the characteristics of a good hypothesis?
consistent with what is already known

testable and possibly falsifiable with evidence
What is falsifiability?
if we claim something is scientifically true, we must be able to specify what evidence it would take to prove it wrong
Who was the first to see and name cells?
Robert Hooke
Which scientists concluded that "all organisms were composed of cells"?
Matthias Schleiden and Theodor Schwann

first tenet of cell theory
Which scientists greatly improved compound microscopes by eliminating blurry edges (spherical aberration) and rainbowlike distortions (chromatic aberration)?
Carl Zeiss and Ernst Abbe
Which method is described as making numerous observations until one becomes confident in drawing generalizations and predictions from them?
The Inductive Method --> Francis Bacon

knowledge of anatomy is obtained by this method
Which philosophers invented new habits of scientific thought?
Francis Bacon in England
Rene Descartes in France
Which method allows for more physiological knowledge and includes the investigator asking a question, formulating a hypothesis, and falsifiability?
Hypothetico-Deductive Method
What is the term that describes effects of the subject's state of mind on his or her physiology?
psychosomatic effects --> use of placebo in control group
How can experimenter bias be prevented?
in a double-blind study where neither the doctor nor the patient know
What aspects of experimental design that help to ensure objective and reliable results?
sample size - number of subjects used in a study

controls - control group and treatment group

psychosomatic effects - effects of the subject's state of mind on his or her own physiology

experimenter bias - prevented with double-blind study

statistical testing - provides statements of probability
What is the term that describes the critical evaluation by other experts in the field?
peer review

ensures honesty, objectivity, and quality in science
What is the term that describes information that can be independently verified by a trained person?
scientific fact
What is the term that describes a generalization about the predictable way matter and energy behave?
law of nature

results from inductive reasoning and repeated observations; written as verbal statements or mathematical formulas
What is the term that describes an explanatory statement or set of statements derived from facts, laws, and confirmed hypotheses?
theory

summarizes what we know; suggests direction for further study
What book written by Charles Darwin has been coined "the book that shook the world"?
On the Origin of Species by Means of Natural Selection
What is the term that describes how species originate and change through time, which changed the prevailing view of our origin, nature, and our place in the universe?
theory of natural selection
What is the term that describes the change in genetic composition of population of organisms?
evolution
What term explains the development of resistance to antibiotics and the appearance of new strains of AIDS virus?
evolution
What is the term that describes some individuals within a species having hereditary advantage over their competitors?
natural selection

better camouflage
disease resistance
ability to attract mates
What is the term that describes natural forces that promote the reproductive success of some individuals more than others?
selection pressures
What is our closest relative?
chimpanzee --> difference of only 1.6% in DNA structure
What is the term that describes features of an organism's anatomy, physiology, or behavior that have evolved in response to those selection pressures and enable the organism to cope with the challenges of its environment?
adaptations
What is the term that describes remnants of organs that apparently were better developed and more functional in the ancestor of a species, and now serve little or no purpose?
vestigial organs

pileorector muscles
auricularis muscles
What is the term that describes the order of mammals to which humans, monkeys, and apes belong?
primates
What is the term that describes the body's ability to detect change, activate mechanisms that oppose it, and thereby maintain relatively stable internal conditions?
homeostasis
Which adaptation made hands prehensile to grasp branches and encircle them with the thumb and finger?
opposable thumbs
List the adaptations for arboreal (treetop) lifestyle of earlier primates?
mobile shoulders

opposable thumbs (prehensile hands)

forward-facing eyes (stereoscopic vision)

color vision

larger brains and good memory
What is the term that describes the ability of present primates to stand and walk on two legs?
bipedalism
What are the adaptations for bipedalism?
skeletal and muscular modifications

increased brain volume

family life and social changes
What is the oldest bipedal primate?
Australopithecus
Which homo species appeared 2.5 million years ago and were taller, had larger brain volume, probably speech, and tool-making?
Homo genus
Which homo species appeared 1.8 million years ago and migrated from Africa to parts of Asia?
Homo erectus
Which homo species originated in Africa 200,000 years ago?
Homo sapiens
Describe the hierarchy of complexity.
Organism
Organ system
Organs
Tissues
Cells
Organelles
Molecules
Atoms
What is the term that describes the theory that a large, complex system such as the human body can be understood by studying the simpler components?
Reductionism (first espoused by Aristotle)
What is the term that describes the theory that there are "emergent properties" of the whole organism that cannot be predicted from the properties of the separate parts?
Holism

Humans are more than the sum of their parts
No two humans are exactly alike. _____% most common structure and ______% anatomically variant.
70% most common structure and 30% anatomically variant.

Variable number of organs. Variation in location of organs.
What is the term that describes that living things exhibit a higher level of organization than the nonliving world around them?
organization
What is the term that describes that living matter is always compartmentalized into one or more cells?
cellular composition
What is the term that describes the sum of all internal chemical change: anabolism, catabolism, and excretion?
metabolism
What terms describe sense and react to stimuli (responsiveness, irritability, and excitability)?
responsiveness and movement
What is the term that describes mutations: changes in genetic structure?
evolution
What is the term that describes the smallest unit of an organism that can carry out all functions of life?
cell
What the term that describes a molecule, cell, organ that directly carries out a response to a stimulus?
effector
What is the term that describes the smallest part of matter with unique chemical properties?
atom
Which 5 factors cause physiological variation?
sex, age, diet, weight, physical activity
Describe the physiological values of the reference man.
22 years old, 154 lbs, light physical activity
consumes 2,800 kcal/day
Describe the physiological values of the reference woman.
22 years old, 128 lbs, and 2,000 kcal/day
What can the failure to consider physiological variation lead to?
overmedication of elderly or medication women on the basis of research done on men
What is the range of internal body temperature despite variations in external temperature?
97-99 degrees F

(Claude Bernard)
Which scientist coined the term homeostasis?
Walter Cannon

State of the body fluctuates (dynamic equilibrium) within limited range around a set point.
Which mechanism is activated when the body senses a change and wants to reverse it to maintain dynamic equilibrium?
negative feedback
Which mechanism is triggered when the brain senses a change in blood temperature?
negative feedback
What is the term that describes the process that occurs when vessels dilate in the skin and sweating begins (heat-losing mechanism)?
vasodilation
What is the term that describes the process that occurs when vessels in the skin constrict and shivering begins (heat-gaining mechanism)?
vasoconstriction
What sends nerve signals that increase the heart rate and return the blood pressure to normal; regulates heart rate?
cardiac center
What is the term that describes sensory nerve endings in the arteries near the heart that alert the cardiac center in the brainstem?
baroreceptors
What senses changes in the body?
receptors (e.g. stretch receptors that monitor blood pressure)
What is the control center that processes sensory information, "makes a decision", and directs the response?
integrating (control) center (e.g. cardiac center of the brain)
What carries out the final corrective action to restore homeostasis?
effector (e.g. cell or organ)
What mechanism is a self-amplifying cycle that leads to greater change in the same direction?
positive feedback

feedback loop is repeated--change produces more change
At what temperature does fever become fatal?
113 degrees F
What occurs when temperature is above 104 degrees F?
metabolic rate increases

body produces heat even faster

body temperature continues to rise

further increasing metabolic rate
List 5 examples that would result in positive feedback.
childbirth, blood clotting, protein digestion, fever, and generation of nerve signals
What languages do about 90% of medical terms originate?
1,200 Greek and Latin roots
Brachium denotes ______.
arm
Brachii denotes ________.
of the arm
Digiti denotes _________.
of a single finger or toe
Digits denotes _________.
fingers and toes
Digitorum denotes ___________.
multiple fingers or toes
What means "large" in Latin?
magnus
What means "larger of two" in Latin?
major
What means "largest of three being compared" in Latin?
maximus
Which form of medical imaging penetrates tissues to darken photographic film beneath the body, dense tissue appears white, and consists over half of all medical imaging?
Radiography (X-ray)

William Roentgens

Until 1960s, it was the only method widely available.
Which form of medical imaging consists of low-intensity X-rays and computer analysis and creates slice-type images?
Computed tomography (CT scan)

formerly known as a CAT scan
Which form of medical imaging assesses metabolic state of tissue, distinguished tissues most active at any given moment, and injects radioactively labeled glucose?
Positron emission topography (PET scan)
Which form of medical imaging consists of injected or swallowed substances and fills hollow structures?
radiopaque susbtances
Which form of medical imaging is a slice-type image, superior quality to CT scan, best for soft tissue, and alignment and realignment of hydrogen atoms with magnetic field and radio waves?
Magnetic resonance imaging (MRI)
Which form of medical imaging is the second oldest and second most widely used, consists of high frequency sound waves, and avoids harmful X-rays?
sonography