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179 Cards in this Set

  • Front
  • Back

Thyroid Stimulating Hormone




Anterior Pituitary

- Stimulates the secretion of thyroid hormones


- Gland?

Follicle Stimulating Hormone




Anterior Pituitary

- Stimulated ovarian follicle maturation and estrogen production


- Stimulates sperm production


- Gland?

Luteinizing hormone



Anterior Pituitary

- Triggers ovulation and stimulates ovarian production of estrogen and progesterone


- Stimulates testosterone production


- Gland?

Adrenocorticotropic hormone




Anterior Pituitary

- Stimulates the release of glucocorticoids and androgens


- Gland?

Growth Hormone




Anterior Pituitary

- Stimulated body growth and protein synthesis, mobilizes fat and conserves glucose


- Gland?

Prolactin




Anterior Pituitary

- Stimulates milk production (lactation)


- Gland?

Pituitary Gland

- Located in the sella turcica of sphenoid bone


- Dubbed the “master gland” because its hormones control other parts of the endocrine system, namely the thyroid gland, adrenal glands, ovaries, and testes.

Anterior Pituitary

- Secretes many tropic hormones, sometimes called master endocrine gland

Posterior Pituitary

- Not an endocrine gland, acts as a storage area for neurohormones from hypothalamaus

Oxytocin




Posterior Pituitary

- Stimulated powerful uterine contractions during birth and stimulated milk ejection in lactating mothers


- Gland?



Antidiuretic hormone (ADH)




Posterior Pituitary

- Stimulated the kidneys to reabsorb more water, reducing urine output and conserving body water


- AKA vasopressin


- Gland?

Pineal Gland

- Located in roof of third ventricle of brain


- Produces melatonin, which helps maintain circadian rhythm and regulate reproductive hormones

Thyroid Gland

- Located in the throat, just inferior to the larynx


- Its hormones control metabolism, growth, body temperature, muscle strength, appetite, and the health of your heart, brain, kidneys, and reproductive system. Only cells in the body that absorb iodine

Parathyroid Glands

- Two oval glands on posterior side of thyroid


- Regulate calcium levels and have no effect on metabolism

Thyroid Hormone (TH)




Thyroxine T4


Triiodothyronine T3




Thyroid

- Increases basal metabolic rate (BMR); regulates tissue growth and development


- Overall helps regulate body's metabolism by influencing, metabolism, growth, temperature, muscle strength,reproductive system


- Gland?

Calcitonin




Thyroid

- No known physiological role in humans


- Reduces calcium levels in the blood by two main mechanisms: It inhibits the activity of osteoclasts, which are the cells responsible for breaking down bone. Decrease the resorption of calcium in the kidneys, again leading to lower blood calcium levels.


- Gland?

Parathyroid Hormone

- Increases blood calcium by stimulating osteoclasts and by stimulating the kidneys to reabsorb calcium


- Also stimulates kidneys to convert vitamin D to calcitriol, required for the absorption of calcium in the intestines

Thymus

- Bilobed gland situated in the superior thorax, posterior to the sternum and overlying the heart


- Its hormones appear to act locally as paracrines; help mature immune cells in children, usually becomes connective tissue in adults

Pancreas

- Located behind the stomach and close to the small intestine, functions as both endocrine and exocrine


- Produces digestive enzymes as well as insulin and glucagon

Gonads

- Located in the pelvic cavity for females, located outside the pelvic cavity for males

Glucagon




Pancrease

- Accelerates the breakdown of glycogen into glucose, stimulated the conversion of lactic acid into glucose, increases blood glucose levels by stimulating the liver to release


- Stimulated by sympathetic nervous system, targets the liver and adipose tissue


- Produced by alpha cells


- Gland?



Insulin






Pancreas

- Accelerates the transport of glucose into body cells; promotes glycogen, fat and protein synthesis; decreases blood glucose levels


- Stimulated by parasympathetic nervous system


- Produced by beta cells


- Gland?

Estrogens




Ovaries

- Stimulated by Luteinizing hormone and follicle-stimulating hormone


- Targets most cells of the body


- Promotes the maturation of the female reproductive organs, and the development of secondary sex characteristics


- Gland?

Estrogens and Progesterone together




Ovaries

- Regulate the menstrual cycle and promote breast development


- Stimulated by LH and FSH from anterior pituitary


- Targets uterus and mammaries


- Gland?

Testosterone




Testes

- Promotes the maturation of the male reproductive organs, the development of secondary sex characteristics, sperm production and sex drive


- Stimulated by LH and FSH, targets most cells of the body

Parafollicular/C Cells from Thyroid Gland

- Calcitonin is produced by what cells from which gland?

- Oxyphils (Scattered, much larger)


- Parathyroid Cells (Small and abundant)

List and describe the 2 structures under a Parathyroid gland slide?

Acinar cells (Numerous, darker)


Islets of Langerhans (Roughly circular area, lighter)


Alpha cells (Stain darker)


Beta Cells (Stain lighter)

List and describe the 4 structures under Pancreas slide?

- Acidophil cells (Reddish pink)

- Basophil cells (Blue/purple)


- Chromophobes (Colorless)

List and describe the 3 cells under the anterior pituitary slide?

Acidophile cells



Basophil cells

Prolactin and Growth hormone is produced from which cells?




FSH, ADH, TSH and LH is produced from which cells?

- Pituicytes (Flattened cells)

- Nerve Fibers

List and describe the 2 structures in the posterior pituitary.

Acinar cells

What are the cells that secrete exocrine products in the pancreas?

Hormones

Secreted from an endocrine organ into the blood to their target cells by binding to receptors and cause a response by stimulating or inhibiting a pathway.

- Adrenal cortex

- Thyroid


- Melatonin can act like both

List the 3 glands that secrete steroid hormones (or act like steroid hormones)

- Anterior Pituitary

- Thyroid


- Adrenal Cortex


- Gonads

4 Glands with Hormonal control

- Posterior Pituitary

- Pineal


- Adrenal medulla



3 Glands with Neural Control

- Parathyroid

- Pancreas


- Thymus



3 Glands with Humoral Control

- Water

- Electrolytes


- Plasma Proteins


- Substances transported by blood




55

4 Major Components of Plasma (Total %?)

Sodium


Potassium


Calcium


Chloride


Magnesium


Bicarbonate




- Osmotic Balance, pH buffering

6 Electrolytes in Plasma and their overall function

Albumin - Osmotic Balance

Fibrinogen - Blood clotting


Globulins - Antibodies, lipid transport

3 Plasma Proteins and their individual functions

Nutrients (Glucose, fatty acids, amino acids, vitamins)

Waste Products (Urea)


Respiratory Gases (O2, CO2)


Hormones

4 Substances Transported by Blood and give examples

Erythrocytes

- Transports oxygen and helps transport carbon dioxide


- Biconcave, anucleate

Leukocytes

- Function is for Defense and immunity

Platelets

Function is to help in blood clotting

Neutrophils

- Multilobed nucleus, red and blue granules

- Phagocytizes pathogens or debris

Eosinophil

- Bilobed nucleus, red cytoplasmic granules


- Kills parasitic worms; slightly phagocytic; complex role in allergy and asthma

Basophil

- Lobed nucleus, blue/purple cytoplasmic granules


- Releases histamine and other mediators of inflammation; contains heparin, an anticoagulant

Lymphocyte

- Spherical nucleus, pale blue cytoplasm


- Mount immune response by direct cell attack or via antibody production

Monocyte

- U- or kidney shaped nucleus, gray-blue cytoplasm, biggest WBC


- Develop into macrophages in tissues and phagocytize pathogens or debris

Agranulocytes

- Although found in the bloodstream, much more abundant in lymphoid tissues

Differential White Blood Count

- 100 WBCs are counted and classified according to type

Neutrophils

Lymphocytes


Monocytes


Eosinophils


Basophils

List the leukocytes in descending order of frequency

- Neutrophil


- Eosinophil


- Monocyte

3 Phagocytic Leukocytes

- Superior to diaphragm

- Thoracic Cavity


- Mediastinum

The heart is located superior to the ________________, in the _____________ cavity, in the ____________

Fibrous pericardium

Serous Pericardium


- Parietal Layer


- Visceral Layer (Epicardium)


Myocardium


Endocardium

Name the layers of the heart:


- Superficial double-walled sac?


- Deep lining of double walled sac?


- Deep lining consists of another superficial and deep layer, these are called?


- Name the 3 layers of the heart walls

Myocardium

- Thickest layer, composed mainly of cardiac muscle


- Reinforced with dense irregular connective tissue, the cardiac skeleton

Endocardium

- Covers the heart valves and its continuous with the inner lining of the great vessels


- Composed of simple squamous epithelium resting on areolar connective tissue

Interventricular septum

- AKA interatrial


- Thick muscle wall that divides the heart longitudinally

Chordae tendineae

- Tiny white collagenic cords anchoring papillary muscles

- Tricuspid


- Mitral (Bicuspid)


- Pulmonary


- Aortic

- Right atrioventricular valve


- Left antrioventricular valve


- Right semilunar valve


- Left semilunar valve

Ligamentum arteriosum

- Fibrous tissue that connects to the aorta and the left pulmonary artery

Introventricular sulcus (Anterior)




Left coronary artery


Great Cardiac Vein

- Groove that separates the ventricles of the heart


- 2 Blood vessels that run along this groove

Left coronary artery

First branch of the ascending aorta and passes posterior to the pulmonary trunk

Coronary sulcus




Right and Left Coronary artery, Great Cardiac Vein

- Groove that separates the atria and the ventricles of the heart


- What 3 blood vessel runs along here?

Anterior cardiac vein

What major vein branches form the right coronary artery?

Fossa Ovalis

- Depression in the right atrium of the heart, at the level of the interatrial septum, the wall between right and left atrium

Coronary Sinus

- Right atrium receives oxygen-poor blood from the heart from this major vessel


- Located along the coronary sulcus on posterior surface of heart

Heart Murmurs

- This is caused when blood can't be pumped through the valves properly, body can’t be properly oxygenated


- Swishing or screeching

Electrocardiogram

- Measures electrical activity of the heart: Involuntary contraction because self-regulated

Serous Fluid

- Fluid produce from pericardium layers (Sac) allows the heart to beat in a relatively frictionless environment

Inspiration/Inhalation

Taking in a breath

Expiration/Exhalation

Releasing a breath

Tidal Volume (TV)

Normal volume inhaled/exhaled per breath (Male = Female)

Inspiratory Reserve Volume (IRV)

Maximum volume you can inhale in a breath after normal exhalation (Male>Female)

Expiratory Reserve Volume (ERV)

Maximum volume you can exhale after normal inhalation (Male>Female)

Residual Volume (RV)

Air remaining in lungs after forcefully exhaling (Male>Female)

Vital Capacity (VC)

Maximum volume you can exhale after a maximum inhalation (Male>Female)

Tidal Volume

Respiratory Volume that Male = Female

Tidal Volume + Inspiratory Reserve Volume + Expiratory Reserve Volume

Equation for Vital Capacity

Pancrease

- Organ that helps regulate blood glucose levels by releasing hormones in blood vessels

Mesenteric Arteries

- Vessels that supply blood to the intestines

Hepatic Portal Vein

- Vessel that brings blood from the intestines straight to the liver

Hepatic Vein

- Vessel that brings blood from liver to inferior vena cava

Insulin

- Hormone that lowers blood glucose by stimulating liver to store glucose as glycogen

Glucagon

- Hormone that raises blood glucose by stimulating liver to break down glycogen and release glucose

No Glucose

After addition of Benedict's Reagent, the sample is blue. This is an indication of?

Low Glucose

After addition of Benedict's Reagent, the sample is green. This is an indication of?

High Glucose

After addition of Benedict's Reagent, the sample is red/orange. This is an indication of?

Vena Cavae

Which vessel is easier to stretch? Aorta or Vena cava?

Depolarization
When the voltage in the cell membrane rapidly moves toward zero

Intrinsic Conduction System

- Ensures that the heart muscle depolarizes in an orderly and sequential manner, from atria to ventricles, and that the heart beats as a coordinated unit

Sinoatrial Node

- Pacemaker of the heart, set's heart rhythm because has the most leaky Na+ channels, Na+ constantly diffusing into cells


- When threshold reached, voltage-gated channels open, depolarizes


- Leads to atrial depolarization/contraction


- Sends electrical impulse through atrioventricular bundle to AV node through bundle of His


- Bundle branches carry signal to apex of heart


- Purkinje fibers bring signal to external ventricular walls

Atrioventricular Node

- Impulses pause (0.1 sec) here after the sinoatrial node generates impulses

Atrioventricular Bundle (Bundle of His)

Conducts the impulses to the bundle branches

Bundle Branches

- Conducts the impulses through the interventriclar septum and right and left of heart

P Wave

- Phase of atrial depolarization

P-Q/P-R Interval

- Time between atrial depolarization and ventricular depolarization

R Wave

- Phase of ventricular depolarization

QRS Interval

- Entire time excitation and depolarization from bundle of His - bundle branches - Purkinje fibers

ST segment

- Myocardial depolarization and contraction

T Wave

- Phase of ventricular repolarization

QT Interval

- Ventricular electrical activity (depolarization to repolarization)

Tachycardia




Bradycardia

- Heart rate over 100 beats/min




- Heart rate below 60 beats/min

Fibrillation

- Condition of rapid uncoordinated heart contractions

Stroke Volume

- Amount of blood ejected by a ventricle with each contraction

Arteries

- Typically thicker and more muscular because have higher blood pressure, pressure remains at arterioles, almost at zero at capillaries


- Except for pulmonary, carries oxygenated blood

Capillaries

- Site of exchange between blood and tissue cells


- Only tunica intima

Veins

- Thin, floppy walls, larger/collapsed lumen


- Valves


- Increases blood again from capillaries by skeletal muscles


- Except for pulmonary, carries deoxygenated blood

Tunica Intima

- Made of single layer of endothelium


- Very thin to allow diffusion of nutrients


- Smooth lining helps decrease resistance to blood flow

Tunica Media

- Most variable because of smooth muscle, thicker in arteries


- Smooth muscle and elastin, active role in regulating diameter of blood vessels, altering peripheral resistance and blood pressure

Tunica Adventitia

- Made of connective tissue, either fibrous or areolar, COLLAGEN


- Supports/protects blood vessels



Parietal Branches of Thoracic Aorta

- Supplies the muscles of thoracic cavity


- Intercostals, superior diaphragm

Visceral Branches of the Thoracic Aorta

- Supplies the organs of thoracic cavity


- Esophageal, bronchial, pericardial

Celiac Trunk

- Supplies the liver, spleen, stomach, gallbladder

Superior Mesenteric

- Supplies the small intestines

Internal Carotid


Vertebral

2 Arteries that supply the Brain

Basilar Artery

- Formed where the two vertebral arteries join at the base of the skull.


- Carries oxygenated blood to the cerebellum, brainstem, and occipital lobe

Circle of Willis

- Anterior and posterior communicating artieries contribute to the formation of the cerebral arterial circle


- Anastomotic system of arteries that sits at the base of the brain and encircles the stalk of the pituitary gland and provides important communications between the blood supply of the forebrain and hindbrain

Subclavian - Axillary - Brachial - Radial & Ulnar




Subclavian - Axillary - Cephalic




Subclavian - Axillary - Basilic - Median antebrachial

Trace venous blood to Subclavian from




- Radial & Ulnar


- Cephalic


- Median Antebrachial

- Left suprarenal and gonadal branch from renal

How is the left renal and right renal veins different in anatomy?

Popliteal

- Small Saphenous


- Posterior Tibial & Fibular


- Anterior Tibial

3 Sources and 4 Vessels of Venous Popliteal Vein

Femoral


Great Saphenous Vein

2 Venous Sources for External Iliac Vein

- External Jugular


- Vertebral


- Internal Jugular

3 Sources for Brachiocephalic Vein

Branches of the Superior Mesenteric Artery

- Middle colic


- Intestinal


- Right colic


- Ileocolic




These are the branches for which vessel?

Systole

Term referring to events of Ventricular contraction

Diastole

Term referring to events of Ventricular relaxation

Cardiac Cycle

- Equivalent to one complete heartbeat during which both atria and ventricles contract and then relax

75 BPM




0.8 seconds

Average heart beats per minute




Length of cardiac cycle

Quiescent Period

- Period of total relaxation (0.4 second)

Dicrotic Notch

- Result of pressure fluctuation that occurs when aortic valve snaps shut


- Point between ventricular systole and diastole


- Isovolumetric relaxation

Electrocardiogram: P Wave, Q-R


Heart Sound: None


Pressure: Aorta Decrease, Atrial Rises - systole


Ventricular Volume: End systolic Volume - Increasing


Valves: AV Valves Open, SL Valves Closed

During ventricular diastole, describe the electrocardiogram, Heat sounds, Pressure of Aorta, Atria, Ventricles, Ventricular Volume, and the Heart Valves

Electrocardiogram: R-S Segment, T Wave


Heart Sound: 1st Heart Sound


Pressure: Aorta Pressure Peaks - Dicrotic Notch, Ventricle Pressure Peaks


Ventricular Volume: End Diastole Volume decrease by Stroke Volume


Valves: AV Valves Closed, SL Valves Open

During ventricular systole, describe the electrocardiogram, Heat sounds, Pressure of Aorta, Atria, Ventricles, Ventricular Volume, and the Heart Valves

'Lub' First Heart Sound

- Assocated with closure of the AV valves at the beginning of ventricular systole

'Dup' Second Heart Sound

- Occurs as the semilunar valves close and corresponds with the end of systole

Auscultate

"Listen to"

Aortic Valve


Pulmonary Valve


Tricuspid Valve


Mitral Valve

- Sounds are heard in 2nd intercostal space at right sternal margin


- Sound are heard in 2nd intercostal space at left sternal margin


- Sounds are typically heart in right sternal margin of 5th intercostal space


- Sounds are heard in 5th intercostal space in line with middle of left clavicle

Pulse Pressure

- Difference between systolic and diastolic pressure

Pulse

- Refers to the alternating surges of pressure (expansion and recoil) in an artery that occur with each contraction and relaxation of the left ventricle

Superficial Temporal Artery: Anterior to the ear, in the temple region


Facial Artery: Clench the teeth and palpate the pulse just anterior to the masseter muscle on the mandible


Common Carotid: At the side of the neck


Brachial Artery: In the cubital fossa


Radial Artery: At the lateral aspect of wrist, above thumb


Femoral Artery: In the groin


Popliteal Artery: At back of the knee


Posterior Tibial Artery: Above medial malleolus


Dorsalis Pedis Artery: On dorsum of foot

Know what and where the 9 Superficial Pulse Points are.


Pulse point with greatest and least amplitude?

Blood Pressure




Cardiac Output * Peripheral Resistance (COPR)

Defined as the pressure the blood exerts against any unit area of the blood vessel wells and is generally measured in the arteries




What is its equation?

Systolic Pressure

- Pressure in the arteries at the peak of ventricular contraction (mmHg)

Diastolic Pressure

- Reflects the pressure during ventricular relaxation (mmHg)

Sphygmomanometer

- Blood pressure cuff - an instruments used to obtain blood pressure readings by the auscultatory method

Sounds of Korotkoff

- As cuff pressure is gradually released, characteristic sounds indicating the resumption of blood flow


- Soft thudding sounds of the blood spurting through the partially occluded artery

30




40

Narrowed pulse pressure (less than __ mmHG) may be a signal of severe aortia stenosis, constrictive pericarditis or tachycardia




A widened pulse pressure (over ___ mmHg) common in hypertensive individuals

Mean arterial Pressure

Diastolic Pressure + (Pulse Pressure/3)

- Blood vessel Constriction


- Increase in blood viscosity


- Loss of artery elasticity

3 Factors that increase Peripheral Resistance

Mid-Late Diastole

- Atrial Pressure Rises


- AV Valves open/SL Valves closed


- Ventricles filling with blood


- SA Node depolarizes, stimulates atrial contraction

Systole

- Ventricular Pressure Rises


- AV valves lcosed


- SL valves open


- Isometric contraction: Natural blood flow until arterial pressure equal ventricular pressure


- Ventricular contraction: Pushed blood out of ventricles, "Lub" sound


- Due to electrical system

Early Diastole

- Ventricular Pressure Lowers


- Atrial pressure Rises


- SL valves close as blood back flows from major arteries


- AV valves open - "Dup" sound


- Sodium leaky channels allow influx of Na+ into SA Node

Inspiratory Capacity




TV + IRV

- Maximum amount of air that can be inspired after a normal tidal volume expiration


- Equation?

Functional Residual Capacity




ERV + RV

- Volume of air remaining in the lungs after a normal tidal volume expiration


- Equation?

Total Lung Capacity


IRV+TV+ ERV+RV

- Maximum amount of air contained in lungs after a maximum inspiratory effort


- Equation?

Frontal Sinus

- Act as resonance chambers for speech; warm and moisten incoming air


- Lined with pseudostratified epithelium

Nasal Cavity



- Lined with respiratory mucosa composed of pseudostratified ciliated columnar epithelium; its floor is formed by the heard and soft palates


- Functions to filter, warm and moisten incoming air, resonance chambers for voice production


- Contains 3 Nasal Conchae

Nasal Conchae


- Superior


- Middle


- Inferior

- Project medially from lateral walls of cavity


- Increases surface area of mucosa, which enhances air turbulence and aids in trapping large particles in the mucus


- Located in Nasal Cavity

Nasopharynx

- Located posterior to nasal cavity, lined with pseudostratified ciliated columnar epithelium


- Contains pharyngeal tonsil, provide protection against pathogens


- Provides for the passage of air from the nasal cavity

Oropharynx

- Posterior to oral cavity, extends from soft palate to epiglottis; lined with stratified squamous


- Contains palatine tonsils, provide protection against pathogens; and linguial tonsil at base of tongue





Laryngopharynx

- Extends from epiglottis to larynx; stratified squamous


- AKA Voice box


- Diverges into respiratory and digestive branches


- Provides for the passage of air and swallowed food

Larynx

- Tube connecting the laryngopharynx and the trachea


- Above the vocal folds is stratified squamous, below is pseudostratified


- Air passageway; prevents food from entering the lower respiratory tract; responsible for voice production

Thyroid Cartilage

- Large hyaline cartilage, its laryngeal prominence referred to as Adam's apple


- Forms framework of larynx

Cricoid cartilage

- Single ring of hyaline cartilage, attaches the larynx to the trachea via the cricotracheal ligament

Epiglottis

- Single flap of elastic cartilage anchored to the inner rim of thyroid cartilage


- "Guardian of the airways" forms a lid over the larynx during swallowing

Vocal folds (true vocal cords)

- Composed of mostly elastic fibers covered with mucous membrane, glottis runs through here


- Vibrate with expired air for sound production

Vestibular folds (false vocal cords)

- Located superior to vocal folds, protects them and helps to close the glottis when swallowing

Glottis

- Vocal folds and the slitlike passageway between the vocal folds

Trachea

- Cartilage layer except for its posterior; helps movement or obstruction

Conducting Zone

- Moves air from one place to another; mostly heavily supported by cartilage


- Consists of upper and lower respiratory structures

- Nose
- Pharynx
- Larynx

3 Upper Respiratory Structures of Conducting Zone

- Trachea


- Bronchi


- Bronchioles (*Terminal and Respiratory Bronchioles considered part of Respiratory Zone)

3 Lower Respiratory Structures of Conducting Zone

Respiratory Zone

- Gas exchange with blood; no cartilage support; may have some smooth muscle which disappears as this zone continues



- Terminal Bronchioles


- Alveolar ducts


- Alveolar sacs


- Alveoli

4 Respiratory Structures of Respiratory Zone

Primary


Secondary


Tertiary

3 Levels of Bronchi


- Which goes into the lobes of the lungs?

CO2 + H2O <=> H2CO3 (Carbonic Acid) <=> HCO3-(Bicarbonate Ion - Base) + H+(Proton - Weak Acid)

Chemical Equation for CO2 and H2O

- Leads to pH drop (More Acidic)


- Due to increased cellular respiration


- Body adjusts be increasing respiration rate to exhale more CO2

An increase in CO2 leads to? It is due to? Body adjusts how?

Blood Buffering System

- Allows body to adjust respiration to keep pH constant


- Chemoreceptors in body help monitor pH

Carotid Sinus


Aortic Arch


Medulla

3 Chemoreceptors in body to help monitor pH

Muscular Pump


Respiratory Pump

2 Pumps Aiding in Venous Return

Brachiocephalic

Arterial System as one of these; the Venous system has two