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54 Cards in this Set
- Front
- Back
During Implantation (8th day), trophoblastic differentiation occurs creating what two types of cells?
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Cytotrophoblasts -inner
Syncytiotrophoblasts -outer |
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Inner layer of mitotically active mononuclear cells with distinct boundaries
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cytotrophoblasts
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outer mass of cells without cell boundaries known as a syncytium that lack of mitotic activity and are derived from cytotrophoblasts
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syncytiotrophoblasts
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What are syncytiotrophoblasts derived from?
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cytotrophoblasts
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Formed as fluid accumulates between trophoblasts and embryoblasts
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amniotic cavity
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the inner cell mass becomes organized into two layers
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bilaminar germ disc
-epiblasts -hypoblasts |
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layer of columnar epithelium adjacent to the amniotic cavity in the bilaminar germ disc
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Epiblasts
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the cuboidal layer adjacent to the blastocyst cavity now know as the primitive yolk sac in the bilaminar germ disc
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hypoblasts
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blastocyst cavity becomes the ?
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primitive yolk sac
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By the 9th day, only a ? plug demarcates the site of implantation
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fibrin
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By what day does the implantation site covered by endometrium?
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day 12
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By day 9, vacuoles form within the ? and fuse to form lacunar networks.
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Syncytiotrophoblasts
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As the syncytial cells erode away, maternal vessels and blood flow into the lacunar network and initiate ?
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Uteroplacental circulation
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a layer of loosly associated cells form between cytotrophoblasts and the primitive yolk sac.
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Extraembryonic mesoderm
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The coalescence of large cavities that form within the extraembryonic mesoderm
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extraembryonic coelom
(chorionic cavity) |
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The chorionic cavity seperates the extraembryonic mesoderm into?
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extraembryonic SOMATIC mesoderm
extraembryonic VISCERAL mesoderm |
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A person has a "last menstrual period"
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occurs at the implantation site due to increased blood flow into the lacunar networks
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What is the Decidual Reaction?
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swelling of endometrial tissues edema
--> accumulation of glycogen and lipid in the endometrium => immediately surround the embryo and soon incites the entire endometrium |
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What is the ideal implantation site?
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dorsal or ventral wall
near the Fundus (cranial end of uterus) |
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What are the 3 types of ectopic pregnancies?
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Ductal (oviduct)
Internal os Abdominal |
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Placenta pervia is caused by?
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ectopic pregnancy in the Internal Os of the cervix
dangerous during 2nd trimester and at delivery |
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An abdominal ectopic pregnancy usually attaches in the ?
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rectouterine cavity (douglas' pouch)
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Trophoblastic maturation => primary villi
what are they composed up of? |
cytotrophoblastic (fingers)
surrounded by syncytiotrophoblasts |
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Secondary yolk sac is formed from expansion of the ? reshaping the primitive yolk sac
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chorionic cavity
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Connecting stalk expansion of the ? nearly isolates the developing embryo from the trophoblasts except near the caudal end of the embryonic disc
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Chorionic cavity
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Describe the 2nd week:
"rules of 2" |
2 germ layers
-epiblasts -hypoblasts 2 embryonic cavities -amnion -yolk sac 2 trophoblastic layers -cytotrophoblasts -syncitiotrophoblasts |
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a midline indentation of the epiblast surface extending midway into the disc from the caudal end
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primitive streak
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a slightly enlarged indentation at the cranial tip of the primitive streak
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primitive pit
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elevated region that surround the primitive pit
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primitive node / knot
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early invagination of cells through the primitive pit migrate cranially
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prechordal plate
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early invagination of cells through the primitive pit migrate cranially, displace hypoblast, thicken and fuse with the epiblast forming the ?
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oropharyngeal membrane
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Cells of the epiblast proliferate and migrate toward and down through the primitive streak in a process called ?
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invagination
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first wave of invaginating cells that displace the hypoblast cell layer
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embryonic endoderm
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invaginating cells that take residence between the developing embryonic endoderm and the overlying epiblast
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embryonic mesoderm
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epiblasts cells that remain after gastrulation
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embryonic ectoderm
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What is Gastrulation?
When does it occur? |
formation of mesoderm, endoderm, and ectoderm
day 14 - day 19 |
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Suspected remnants of the primitive streak or displaced primordial germ cells
common in what region? |
Teratomas
Sacrococcygeal region |
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Cells invaginating in trhgouh the primitive pit/know form a solid rod of ? this is called the ?
migrates cranially until it abut the prochordal plate/oropharnygeal membrane |
mesoderm
Notochord |
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The notochord serves as the basis of the ?
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axial skeleton in the midline and establishes right and left orientation
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Migrating mesoderm passes around the fused oropharyngeal membrane and a similar caudal epiblast/endoderm fusion called the ?
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cloacal membrane
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True or False
Invaginating cells which become embryonic mesoderm spread cranially, laterally, and caudally. |
True
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Abnormalities in the cranial migration and fusion beyond the prochondral plate of mesoderm cause defects in the development of the ?
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heart
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Abnormalities in the caudal migration and fusion beyond the cloacal membrane of mesoderm cause defects in the ?
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lower abdominal wall
bladder |
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During the formation of the notochord the posterior wall of the secondary yolk sac forms a diverticulum called the ? which extends into the connecting stalk.
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allantois
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What is the role of the allantois?
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may play a role in the induction of ANGIOGENESIS
(blood and blood vessel development) |
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True or False
Germinal disc changes shape -- initially flat and round (frisbee) expands Cranially and laterally to resemble a pear |
True
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Primary villi are penetrated --forming secondary villi by what type of cells?
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extraembryonic somatic mesoderm
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Tertiary villi (definitive villi) give rise to formation of ?
This occurs in the extraembryonic mesoderm of secondary villi |
blood islands and primitive vessels
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? develops vessels that convey blood from the developing placental blood vessels (from villi and the chorionic plate) to the developing embryonic circulation
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connecting stalk
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Within the ? connecting vessels begin to develop the same time that tertiary villi are emerging.
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Chorionic Plate
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REMEMBER
chorionic plate tertiary villi connecting stalk all give rise to blood structure |
REMEMBER
chorionic plate tertiary villi connecting stalk all give rise to blood structure |
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cytotrophoblasts that have penetrated through the syncytium to the decidua
--firmly attaching the chorion (placenta) to the endometrium |
Cytotrophoblastic shell
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Villi which extend from the chorionic plate to the decidua
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stem / anchoring villi
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Side branches of villi exxtending from the anchoring villi
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free villi
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