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54 Cards in this Set

  • Front
  • Back
During Implantation (8th day), trophoblastic differentiation occurs creating what two types of cells?
Cytotrophoblasts -inner

Syncytiotrophoblasts -outer
Inner layer of mitotically active mononuclear cells with distinct boundaries
cytotrophoblasts
outer mass of cells without cell boundaries known as a syncytium that lack of mitotic activity and are derived from cytotrophoblasts
syncytiotrophoblasts
What are syncytiotrophoblasts derived from?
cytotrophoblasts
Formed as fluid accumulates between trophoblasts and embryoblasts
amniotic cavity
the inner cell mass becomes organized into two layers
bilaminar germ disc

-epiblasts

-hypoblasts
layer of columnar epithelium adjacent to the amniotic cavity in the bilaminar germ disc
Epiblasts
the cuboidal layer adjacent to the blastocyst cavity now know as the primitive yolk sac in the bilaminar germ disc
hypoblasts
blastocyst cavity becomes the ?
primitive yolk sac
By the 9th day, only a ? plug demarcates the site of implantation
fibrin
By what day does the implantation site covered by endometrium?
day 12
By day 9, vacuoles form within the ? and fuse to form lacunar networks.
Syncytiotrophoblasts
As the syncytial cells erode away, maternal vessels and blood flow into the lacunar network and initiate ?
Uteroplacental circulation
a layer of loosly associated cells form between cytotrophoblasts and the primitive yolk sac.
Extraembryonic mesoderm
The coalescence of large cavities that form within the extraembryonic mesoderm
extraembryonic coelom

(chorionic cavity)
The chorionic cavity seperates the extraembryonic mesoderm into?
extraembryonic SOMATIC mesoderm

extraembryonic VISCERAL mesoderm
A person has a "last menstrual period"
occurs at the implantation site due to increased blood flow into the lacunar networks
What is the Decidual Reaction?
swelling of endometrial tissues edema

--> accumulation of glycogen and lipid in the endometrium

=> immediately surround the embryo and soon incites the entire endometrium
What is the ideal implantation site?
dorsal or ventral wall

near the Fundus (cranial end of uterus)
What are the 3 types of ectopic pregnancies?
Ductal (oviduct)

Internal os

Abdominal
Placenta pervia is caused by?
ectopic pregnancy in the Internal Os of the cervix

dangerous during 2nd trimester and at delivery
An abdominal ectopic pregnancy usually attaches in the ?
rectouterine cavity (douglas' pouch)
Trophoblastic maturation => primary villi

what are they composed up of?
cytotrophoblastic (fingers)

surrounded by syncytiotrophoblasts
Secondary yolk sac is formed from expansion of the ? reshaping the primitive yolk sac
chorionic cavity
Connecting stalk expansion of the ? nearly isolates the developing embryo from the trophoblasts except near the caudal end of the embryonic disc
Chorionic cavity
Describe the 2nd week:

"rules of 2"
2 germ layers
-epiblasts
-hypoblasts

2 embryonic cavities
-amnion
-yolk sac

2 trophoblastic layers
-cytotrophoblasts
-syncitiotrophoblasts
a midline indentation of the epiblast surface extending midway into the disc from the caudal end
primitive streak
a slightly enlarged indentation at the cranial tip of the primitive streak
primitive pit
elevated region that surround the primitive pit
primitive node / knot
early invagination of cells through the primitive pit migrate cranially
prechordal plate
early invagination of cells through the primitive pit migrate cranially, displace hypoblast, thicken and fuse with the epiblast forming the ?
oropharyngeal membrane
Cells of the epiblast proliferate and migrate toward and down through the primitive streak in a process called ?
invagination
first wave of invaginating cells that displace the hypoblast cell layer
embryonic endoderm
invaginating cells that take residence between the developing embryonic endoderm and the overlying epiblast
embryonic mesoderm
epiblasts cells that remain after gastrulation
embryonic ectoderm
What is Gastrulation?

When does it occur?
formation of mesoderm, endoderm, and ectoderm

day 14 - day 19
Suspected remnants of the primitive streak or displaced primordial germ cells

common in what region?
Teratomas


Sacrococcygeal region
Cells invaginating in trhgouh the primitive pit/know form a solid rod of ? this is called the ?

migrates cranially until it abut the prochordal plate/oropharnygeal membrane
mesoderm

Notochord
The notochord serves as the basis of the ?
axial skeleton in the midline and establishes right and left orientation
Migrating mesoderm passes around the fused oropharyngeal membrane and a similar caudal epiblast/endoderm fusion called the ?
cloacal membrane
True or False

Invaginating cells which become embryonic mesoderm spread cranially, laterally, and caudally.
True
Abnormalities in the cranial migration and fusion beyond the prochondral plate of mesoderm cause defects in the development of the ?
heart
Abnormalities in the caudal migration and fusion beyond the cloacal membrane of mesoderm cause defects in the ?
lower abdominal wall

bladder
During the formation of the notochord the posterior wall of the secondary yolk sac forms a diverticulum called the ? which extends into the connecting stalk.
allantois
What is the role of the allantois?
may play a role in the induction of ANGIOGENESIS

(blood and blood vessel development)
True or False

Germinal disc changes shape --

initially flat and round (frisbee)

expands Cranially and laterally to resemble a pear
True
Primary villi are penetrated --forming secondary villi by what type of cells?
extraembryonic somatic mesoderm
Tertiary villi (definitive villi) give rise to formation of ?

This occurs in the extraembryonic mesoderm of secondary villi
blood islands and primitive vessels
? develops vessels that convey blood from the developing placental blood vessels (from villi and the chorionic plate) to the developing embryonic circulation
connecting stalk
Within the ? connecting vessels begin to develop the same time that tertiary villi are emerging.
Chorionic Plate
REMEMBER

chorionic plate
tertiary villi
connecting stalk

all give rise to blood structure
REMEMBER

chorionic plate
tertiary villi
connecting stalk

all give rise to blood structure
cytotrophoblasts that have penetrated through the syncytium to the decidua

--firmly attaching the chorion (placenta) to the endometrium
Cytotrophoblastic shell
Villi which extend from the chorionic plate to the decidua
stem / anchoring villi
Side branches of villi exxtending from the anchoring villi
free villi