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103 Cards in this Set

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Consists of three interrelated components: blood, the heart, blood vessels.
Cardiovascular system.
A connective tissue composed of a liquid extra-cellular matrix called blood plasma that dissolves and suspends various cells and cell fragments:
Blood.
The fluid that bathes body cells and is constantly renewed by the blood:
Interstitial fluid.
List the functions of blood:
-Transportation
-Regulation
-Protection
List the physical characteristics of blood.

Temperature?
38* Celsius/100.4* Fahrenheit
List the physical characteristics of blood.

pH?
Slightly alkaline, 7.35 to 7.45.
List the physical characteristics of blood.

Volume?
5-6 liters in males (1.5 gallons)
4-5 liters in females (1.2 gallons)
List the components of blood:
Blood plasma, formed elements.
Straw colored liquid left after formed elements are removed from blood:
Blood plasma.
Proteins in plasma confined in blood; play a role in maintaining proper blood osmotic pressure:
Plasma proteins.
Hepatocytes (liver cells) synthesize most of the plasma proteins which include:
Albumins (54%)
Fibrinogen (7%)
Globulins (38%)
Certain blood cells develop into cells that produce gamma globulins; are produced during certain immune responses:
Antibodies/immunoglobins.
An antibody binds specifically to a foreign substance that stimulates its production:
Antigen.
The formed elements of the blood contain these three principal components:
Red blood cells (RBC)
White blood cells (WBC)
Platelets
The percentage of total blood volume occupied by RBC?
Hematocrit: ___ % of volume of blood are RBC's.
The process by which the formed elements of blood develop:
Hemopoiesis
Another name for red blood cells
Erythrocytes
The oxygen-carrying protein in blood that gives whole blood its red color
Hemoglobin
A hemoglobin consists of a protein called globin, composed of four polypeptide chains and a ringlike nonprotein pigment called a ____ is bound to each of the four chains.
Heme
The chemical symbol for Iron is:
Fe
The life cycle of a red blood cell
120 Days
When iron is removed from heme, the non-iron portion of heme is converted to ______ (a green pigment) and then into _____ (a yellow orange pigment).
Biliverdin (green)
Bilirubin (yellow orange)
The production of red blood cells that starts in the red bone marrow
Erythropoiesis
Cellular oxyden deficiency that occurs if too little oxygen enters the blood:
Hypoxia
Another name for white blood cells
Leukocytes
Name the types of granular leukocyctes
Granular:
-neutrophil
-eosinophil
Name the two types of agranular leukocytes
Agranular:
-lymphocyte
-monocyte
The process of ingesting of bacteria and disposing of dead matter:
Phagocytosis
A count of each of the 5 white blood cells, to detect infection or inflammation...
Differential WBC Count
Megakaryoblasts transform into megakaryocytes, huge cells that splinter into 2000-3000 fragments. Each fragment, enclosed by a piece of the cell membrane is a ________; these help stop blood from damaged blood vessels by forming a plug.
Platelets (thrombocyte)
The sequence of responses that stops bleeding:
Hemostasis
The loss of a large amount of blood from the vessels:
Hemorrhage
Straw colored liquid that is blood plasma MINUS THE CLOTTING PROTEIN
Serum
Gel that consists of a network of insoluble protein fibers called fibrin in which the formed elements of blood are trapped:
Clot
The process of gel formation; a series of chemical reactions that culminates in formation of fibrin threads:
Clotting (coagulation) factors
Normal clotting depends on an adequate amount of:
Vitamin K
A clot itself is known as a
Thrombus
A blood clot, bubble of air, fat from broken bones or a piece of debris transported by the blood steam is called an
Embolus
Based upon the presences or absence of various antigens; blood is categorized into
Blood Groups
Within a given blood group, there are two or more different
Blood types
Based on two glycolipid antigens called A and B
ABO Blood Group
People whose RBC displays only antigen A are:
Type A
People whose RBC displays only antigen B are:
Type B
People who have both A and B antigens are
Type AB
People who have neither A nor B are
Type 0
Named because of the antigen discovered in the Rhesus monkey
Rh blood group
The transfer of whole blood or blood components (red blood cells or plasma only) into the bloodstream or directly into red bone marrow:
Transfusion
If an Rh negative person receives an Rh positive blood transfusion, the immune system starts to make anti-Rh antibodies that will remain in the blood. If a second transfusion of Rh positive blood is given later, the previously formed anti-Rh antibodies will cause agglutination and ______ of the RBC's in the donated blood and a severe reaction may occur.
Hemolysis
The most common problem with Rh incompatibility; may arise during pregnancy
Hemolytic disease of the newborn (HDN)
Even while you are sleeping ,your heart pumps ____ it's own weight each minute, or ____ each minute, which amounts to more than 14,000 liters (3,600 gallons) of blood in a day.
30x

5 liters (5.3 quarts)
The study of the heart and the diseases associated with it:
Cardiology
The membrane that surrounds and protects the heart:
The pericardium
A deeper, thinner and more delicate membrane that forms a double layer around the heart:
serous pericardium
Outer layer of the serous pericardium that is fused to the fibrous pericardium:
Parietal layer
The inner layer of the serous pericardium; one of the layers of the heart wall and adheres tightly to the surface of the heart.
Visceral layer, epicardium
Space that contains the few milliliters of pericardial fluid:
Pericardial cavity
External layer of the heart
Epicardium
Middle layer of the heart, cardiac muscle and makes up 95% of the heart, responsible for pumping action
Myocardium
Innermost layer of the heart, thin layer of endothelium overlying a thin layer of connective tissue that provides a smooth lining for the chambers of the heart and covers the valves of the heart:
Endocardium
Away:
Toward:
Artery
Veins
Two superior receiving chambers of the heart:
Atria
Two inferior pumping chambers of the heart:
Ventricles
Receives blood from three veins; the superior vena cava, inferior vena cava and coronary sinus:
Right atrium
An oval depression, remnant of the foramen ovale, opening in the interatrial septum of the fetal heart that normally closes soon after birth:
Fossa ovalis
Blood passes from the RIGHT ATRIUM INTO THE RIGHT VENTRICLE through a valve called the:

This valve consists of three leaflets or cusps
Tricuspid valve
Forms most of the anterior surface of the heart:
Right ventricle
Inside of the right ventricle contains a series of ridges formed by raised bundles of cardiac muscle fibers called
Traberculae Carnaea
"Strings of the heart"
Cusps of the tricuspid valve are connected to tendonlike cords:
Chordae tendinae
Chordae tendinae are conneced to cone-shaped trabeculae carnae called:
Papillary muscles
Blood passes from the RIGHT VENTRICLE THROUGH THIS VALVE INTO A LARGE ARTERY CALLED the pulmonary trunk which divides into the right and left pulmonary arteries:
pulmonary valve
Forms most of the base of the heart
Left atrium
Blood passes from the LEFT ATRIUM INTO THE LEFT VENTRICLE through this two-cusped valve
Bi-cuspid (mitral) valve
Forms the apex of the heart: thickest chamber
Left ventricle
Blood passes from the left ventricle through this valve and into the largest artery in the body; asending aorta:
Aortic valve
Located between an atrium and a ventricle, the triscuspid and bicuspid valves are termed
Atrioventricular valves (AV valves)
Aortic and pulmonary valves are known as
Semilunar valves (SL valves)
With each beat, the heart pumps into two closed circuits with each beat:
Systemic circulation
Pulmonary circulation
Nutrients are not able to diffuse quickly enough from blood in the chambers of the heart to supply all the layers of cells that make up the heart wall. For this reason, the myocardium has its own blood vessels or:
coronary, cardiac circulation
These two branch from the ascending aorta and supply oxygenated blood to the myocardium
right and left coronary arteries
After blood passes through the arties of the corony circulation, it flows into capillaries where it delivers oxygen and nutrients to the heart muscle and collects carbon dioxide and waste and then moves on
Coronary sinus
When two or more arteries supply the same region they usually connect in connections called
Anastomoses
An inherant and rhythmical electrical activity is the reason for a heart's continued beating. Source of this activity is a network of specialized cardiac muscle fibers. These cells are caled:
auto rhythmic fibers/self-excitable
A network of specialized cardiac muscle fibers that provide a path for each cycle of cardiac excitation to progress through the heart. This ensures that cardiac chambers become stimulated to contract in a coordinated manner.
Auto-rhythmic fibers
When cardiac excitation beings:
sinoatrial (SA) node
Recording of electric signals in the heart
EEG, ECK electrocardiogram
Systole
Refers to the contraction within the heart
Diastole
Refers to the relaxation of the heart
Includes all the events associated with one heartbeat
Cardiac cycle
Generated during cardiac cycle (4)
Heart sounds
First (S1) is louder
Lubb
Second (S2) shorter
Dupp
At the beginning of the systemic circulation, blood leaves the heart from this chamber:
Left Ventricle
Pulmonary circulation terminates WITH:
Oxygenated blood
Systemic circulation terminates WITH:
Deoxygenated blood
Pulmonary circulation terminates in the:
Left Atrium
Systemic circulation terminates in the
Right Atrium
Pulmonary circulation begins in the
Right Ventricle
Circulation beginning in the left ventricle
Systemic
Circulation beginning in the right ventricle
Pulmonary
Circulation begins in a
Ventricle
Circulation terminates in an
Atrium
System circulation beings with
Oxygenated
Pulmonary always begins with
Deoxygenated