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32 Cards in this Set
- Front
- Back
what is the main actin filament found in the large cells
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spectrin
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what is the main function of this cell?
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phagocytosis
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what is the immediate precursor of the smaller cells?
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megakaryocytes. platelet demarcation channels mark the boundaries of where the platelets bleb off.
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what is the major enzyme found in the large cell and what is its function?
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carbonic anhydrase. it catalyzes the following reaction: H20 + CO2->H + HCO3
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what is the major protein associated with anion transport in the large cell?
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band 3. aka coupled anion transporter
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what portion of hemoglobin is responsible for oxygen transport? what is the maximum number of oxygen molecules it can transport?
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Heme (iron). 4 is the max
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the large cell does not have MHC molecules to allow for self recognition. What are the two alternative sets of self recognition proteins it uses?
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A, B and Rh
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what is the immediate precursor of the large cell?
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reticulocyte
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where is the place of origin of the large cell?
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red bone marrow
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what is the major place of storage of the smaller cell?
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spleen
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what are some of the major enzymes associated with this cell and what are their functions?
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Collagenase-degrades ECM of bacteria
Defensins- act like antibodies Myeloperoxidases-reacts with hydrogen peroxide to generate potent bacteria killing oxidants (bleach) Lactoferrin-actively binds iron (essential to bacterial nutrition) Lysozyme-breaks down the cell wall of some gram positive bacteria |
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what is the major function of this cell?
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phagocytosis, specifically of antigen/antibody complexes
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what is a major cell surface specialization found on these cells?
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IgE receptors
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how do these cells affect inflammation?
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by inactivating the leukotrienes and himstamine produced by other cells
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what are 2 major proteins associated with the function of these cells and how do they perform this function?
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MBP and eosiniophilic cationic proteins form transmembrane pores in parasites
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what is a major cell surface specialization found on these cells?
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IgE receptors
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what are the azurophilic granules located in these cells?
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lysosomes
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what is the function of this cells?
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differentiate into macrophages. phagocytosis
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what is the origin of this cell?
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MPS
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what is the immediate precursor of this cell?
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promonocyte
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is this cell capable of mitosis
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no
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what is the immediate precursor of this cell?
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neutrophilic band
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is this cell capable of mitosis?
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no
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what is the origin of this cell?
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red bone marrow
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what type of intermediate filament is found specifically in this cell?
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vimentin
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what is the immediate precursor?
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eosinophilic band
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what is the origin of this cell?
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bone marrow
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is this cell capable of mitosis?
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no
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what is the process of production of the large cell called? what is the name of the growth that initiates this process? where is the growth factor made?
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erythropoiesis, erythropoietin, KIDNEY!
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what is the process of making the smaller cells called? what is the growth factor associated with it? where is the growth factor manufactured?
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thrombopoiesis, thrombopoietin, bone marrow and LIVER
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what is the CFU for the production of the large cells?
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BFU-E for fast spurts; CFU-E for constant production
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what is the CFU for the smaler cells?
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CFU-Meg
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