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78 Cards in this Set

  • Front
  • Back
What is the major difference between endocrine and exocrine glands?
endocrine glands secrete their hormones into interstitial fluid while exocrine glands secrete their products into ducts to the outside of the body
give an example of an exocrine gland
1. salivary gland
2. submandibular gland
3. sebacious oil gland
etc.
What is the function of the endocrine system?
to regulate body activity
Name the 2 discrete endocrine glands?
1. thyroid
2. adrenal cortex
Who secretes erythroppoietin?
kidney
who secretes ANP?
atria
Who secretes leptin?
adipose cells
Which 2 hormones does the hypothalamus produce?
1. oxytocin
2. ADH
Which hormone works on many different cells as oppose to one target cell type?
thyroid hormone
Define circulation hormones
hormone produced by a gland then to blood then to wherever it needs to do its job
what does the liver eventually do to circulation hormones?
inactivates and eliminates them
Which 2 categories are hormones classified into?
1. solubility
2. chemical form
What are the three chemical forms that hormones are divided into?
1. proteins
2. amines
3. steroids
What are the 2 protein hormones?
1. PTH
2. pituitary gland hormones
Which hormones are included in the amines?
adrenal medulla hormones
which hormones are included in steroids?
1. sex hormones
2. adrenal cortex hormones
Define Local Hormones
Hormones secreted by particular cell and change activity of cell that secreted them or a neighboring cell.
Define autocrines
hormones that affect the activity of the cell that secreted it
Define Paracrines
hormones that affect the cell activity of a neighboring cell
What hormone is the only hormone with a positive feedback loop?
oxytocin
What are the 2 regions of the pituitary gland?
1. anterior pituitary
2. posterior pituitary
What is another name given to the pituitary gland?
hypophysis
What is another name given to the anterior pituitary?
adenohypophysis
What is another name given to the posterior pituitary?
Neurohypophysis
What attaches the pituitary gland to the hypothalamus?
infundibulum
What is the function of the hypophyseal portal system?
to carry out secretions from the hypothalamus to the posterior pituitary gland through veins in the infundibulum
What is the general function of the posterior pituitary?
to store and secrete hormones made by the hypothalamus
What are the 2 hormones secreted by the posterior pituitary?
1. ADH
2. Oxytocin
What is another name for ADH?
vasopressin
Where are the target cells for ADH?
in the DCT and collecting tubule
What is the major function of ADH?
the reabsorption of water at the DCT and collecting duct
What is the problem in someone with diabetes insipidus?
they are not producing ADH
what do large amounts of alcohol do to ADH?
they inhibit the secretion of it
What are the 2 functions of oxytocin?
1. to maintain uterine contractions
2. responsible for milk let-down
What is the function of the hormones that are produced in the anterior pituitary?
to regulate activity of other endocrine glands
Define tropin
a hormone that regulates the activity of another endocrine gland
What controls the anterior pituitary?
the hypothalamus
What is the "master gland?"
hypothalamus
What is another name for growth hormone (GH)?
somatotropin
What is the function of GH?
to stimulate body cells to grow and divide
What are the target cells of GH?
skeletal muscle cells and bone cells
What hormone increases cellular uptake of amino acids?
growth hormone
Which hormone stimulates ANP 1 for long growth of bone?
growth hormone
GH mobilizes fat for _________
gluconeogenesis
Secretion of GH is regulated by what?
releasing factors or inhibiting factors
What are the secondary factors involved growth hormone?
1. nutritional status
2. sleep
3. adolescence is when it peaks
When is the most GH secreted?
during sleep
What are the 4 disorders of growth hormone?
1. giantism
2. dwarfism
3. acromegaly
4. progeria
Define acromegaly
overproduction of GH in adults
Define Progeria
severe underproduction of GH in adults and children
Give another name for thyroid stimulating hormone
thyrotropin
What controls the secretion of TSH?
thyrotropin releasing factor
What are the 2 functions of TSH?
1. to stimulate normal development of the thyroid gland
2. to stimulate production of thyroid hormones
Which 6 hormones are secreted by the anterior pituitary?
1. tropin
2. thyroid stimulating hormone
3. ACTH
4. follicle stimulating hormone
5. lutenizing hormone
6. Prolactin
What is the function of ACTH?
to go to the adrenal cortex and stimulate the secretion of glucocorticoids
What is the full name for ACTH?
adrenocorticotropic hormone
What secondary factors stimulate secretion of ACTH?
1. low blood glucose
2. stress
which releasing factor controls ACTH?
corticotropic RF
Where is corticotropic RF secreted from?
hypothalamus
What releasing factor is associated with follicle stimulating hormone?
gonadotropin
What does FSH do in ovaries?
1. stimulates production of estrogen
2. stimulates maturation of ovum
What does FSH do in Testes?
stimulates the production of androgen binding protein, which binds to testosterone
Which releasing factor is associated with lutenizing hormone?
gonadotropin
What is the function of lutenizing hormone (LH) in females?
1. to finalize maturation of ovum
2. to maintain corpus luteum
What does the corpus luteum produce?
estrogen and progesterone
What is another name for lutenizing hormone in the male?
interstitial cell stimulating hormone (ICSH)
What is the function of LH in males?
to tell testes to secrete testosterone
What's another name for Prolactin
lactogenic hormone
What is the function of prolactin?
1. to stimulate growth an development of breast tissue
2. to initiate and maintain milk secretion from mammary glands
what inhibits the secretion of prolactin?
when estrogen levels are high near the end of a menstrual cycle
What are the islets of langerhans and where are they found?
1. alpha cells
2. beta cells
3. somatostatin
pancreas
What is "going on" in diabetes mellitus?
insulin is unable to be secreted or there is a deficiency of active insulin
What re the 2 categories of diabetes mellitus?
Type I and Type II
What is Type I diabetes mellitus called?
insulin dependent diabetes mellitus
What is Type II diabetes mellitus called?
non-insulin dependent diabetes mellitus
Which diabetes mellitus is considered an autoimmune disorder?
type I
What cells do the antibodies involved in diabetes mellitus type I destroy?
beta cells
Why must you take insulin through injection and not orally???
because the gastric juices would denature the insulin