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97 Cards in this Set

  • Front
  • Back
Three types of muscle tissues?
skeletal, cardiac, smooth
Skeletal Muscle
Striated and voluntary attached to bones
Smooth Muscle
involuntary and non striated located in viscera
Cardiac
striated and involutary and has intercalated discs forms the wall of the heart, its fibers are arranged similarly to skeletal muscle fibers, cardiac muscle fibers connect to adjacent fibers by intercalated discs which contain desmomes and gap junctions4
What the 4 functions of the muscle tissue?
produce body movement, stabilizes, moves substances, and generate heat
What are the four properties of muscle?
electrical exitability, contractility, externsibility, elasticity
Action Potentials (impulses)
electrial signals that go down the axon and the muscle fibers
Electrical excitability
ability to respond to certain stimuli with electrical signals called action potentials
Contractility
ability of muscle tissue to shorten when stimulated by an action potential
Extensibility
ability of muscle to stretch within limits without being damaged
Elasticity
ability for muscle to return to its orginal shape length after extension
Muscle fibers
a muscle cell that is multi nucleated
hypodermis
seperated the muscle from the skin
Fascia
band of dense connective tissue that supports and surrounds muscles and other organs of the body
Three layers of the connective tissue
epimysium, perimysium, endomysium
Epimysium
circles the entire muscle outermost layer
Perimysium
surrounds groups of muscles irregular connective tissues and into fascicles
Fascicles
bundles of muscle fibers surrounded by the perimysium
Endomysium
separates the individual muscle fibers from one another
Tendon
Ropelike and attaches the muscle to the periiosteum of a bone
aponeurosis
connective tissue layers that extend as a broad flat sheet example the epicranial on the skull
Motor Neurons
a neuron that stimulates the muscle fibers to contract
Axon
threadlike process that extends to the skeletal muscle fibers from the bain or spinal cord
Muscular Hypertrophy
enlargment of existing muscle fibers
Muscular Hyperplasia
increase in the number of muscle fibers
Muscular atrophy
decrease in size and strength in the muscle
Satelite cells
fuse together to repair muscle fibers to regenerate functional muscle fibers
Sarcolemma
the plasma membrane of a muscle fiber
transverse (T) tubules
tunnel like invaginations of the sarcolemma that extends toward the center of each musce fiber and filled with intersitial fluid
Sarcoplasm
the sarcolemma surrounds this and it is the cytoplasm of the muscle fiber caontains a large amount of glycogen for energy production and myoglobin for oxygen storage
Myoglobin
red colored protein that binds oxygen molecules,
Myofibrils
contractie element of skeletal muscle extened the entire length of the muscle fiber, contains thick and thin filaments
Sarcoplasmic Reticulum (SR)
fluid filled system of membranous sacs , encircles each myofibril
Terminal Cisterns
dilated end sacs of SR
Triad
one T-tubule and two termina lcisterns
Thin Filaments
made of actin in the I band
Thick Filaments
made of myosin H zone
Sarcomeres
basic functional unit of myofibirls
A band
dark middle portion consists primarily of the thick filaments with some thin overlapping the thick ones
H zone
is in the middle of the A band and contains thick filaments only
zone overlap
wheree thick and thin filaments lie side by side
I band
light area and contains only thin filaments
Z discs
passes throug hthe center of the i band
M line
middle of the sarcomere
Myosin
main componet of thick filaments , a contracile protein that pushes or pulls various cellular structures to achieve moevement converts atp to mechanical energy of motion or force
Actin
main componet in the contractile protein thin filaments connects to the myosin for the sliding together of the filaments
tropomyosin
blocks off myosin binding sites in the thinn filaments
troponin
holds tropomyosin in place in the thin filaments
Titin
key structural protein, third most plentiful in skeletal muscle,, helps a sarcomere return to its resting length after a muslce has contracted or been stretched
Dystophin
a structural protein that links thin filaments of the sarcomere to integral membrane proteins of the sarcolemma
neuromuscular junction (NMJ)
a synapse between a somatic neuron and a skeletal muscle fiber , muscle action potentials arise here
Synapse
a region where communication occurs between the neuron and another cell
Synaptic Cleft
a small gap that seperates the two cells
Synapses
seperates cells from direct physical contact
Neurotransmitters
allow the signal to be transmitted across the gap
Acetylcholine (ACh)
nuerotransmitter at a NMJ
Sliding Filament Mechanism
during muscle contraction myosin heads pull on thin filaments causing them to slide inward toward the M line; z discs come toward each other and the sarcomere shortens, but the thick and thin filaments do not change in length. The sliding of filaments and shortenign of sarcomeres causes the shorotenign fo the whole muscle fibeer and ultimately the entire muscle.
Contraction Cycle ( how it works)
at the beggining of contraction the sarcoplasmic reticulum relases calcium ions which bind to troponin and cause the troponin-tropomyosin complex to uncover the myosin-binding sites on actin, whent the binding sites ar free conrcation begins
Contaction cyle (definiton)
a repeating sequence of events that cause the filaments to slide. It consits of ATP splitting, myosin attachment of myosin to actin, the power stroke, and teh detachment of myosin from actin
Relaxation
2 changes permit the muscle fiber to relax
a. when nerve impulses from the neuron stop, ACh is no longer released into synaptic cleft, this prevents the genneration of a muscle action potential which prevents the relaese of calciium form the sarcomplasmic reticulum.
b. the sarcoplasmic reticulum contains calcium active transport pumps that lowed the concentration of calcium in the sytosol this leads to release of calcium from toponin and moevement of topomyosin to block the myosin binding sites on actin
What is muscle tenison controlled by?
stimulation frequency and motor unit recruitment
When considering the contraction of a whole muscle , what does the tension generate depend on ?
the number of fibers that are contracting in unison
Motor Units
a motor neuron and the muscle fibers it stimulates from, a single motor unit may innervate an average of 150 fibers.
Twitch Contraction
a brief contraction of all muscle fibers in a motor unit in response to a single action potential
myogram
a record of a muscle contraction includes three perios latent, contraciton, and relaxation
Wave Summation
the increased strength of a contraction resulting from the application of a second stimulus before the muscle has completely relaxed after a previous stiumlus
Unfused Tetanus
a sustained muscle contraction that permits partial relaxation between stimuli
Fused Tetanus
a sustained contraction that lacks even partial relaxation between stimuli
Motor Unit Recruitment
process of increasingthe number of active motor units, prevents fatigue and helps provide smooth muscular contraction rather than a series of jerky movements
Muscle Tone
a sustained partial contraction of portions of a relaxed skeletal muscle results in a firmness
Isotonic Contraction
when a constant load is moved through the range of motions possible at a joint include eccentric and concentric
Isometric contraction
the muscle does not shorten but tension increases no movement
Eccentric
in an isotonic contraction pickig up a book
Concentric
in an isotonic contraciton lowering a book
what do muscle fibers create atp from
creatine phospate
how do muscle fibers create ATP
anaerobic and aerobic cellular respiration
How mnay sources for ATP production are there?
three
How long and what for is creatine phospate used for ?
15 seconds and for maximal short burts of energy
anaerobic cellular respiration
partial catabolism of glucose to generate ATP and provide enough energy fro about 30-40 seconds of maximal muscle activity
aerobic cellular respiration
this is uesd for muscular activity lasting longer than 30 seconds , requirs oxygen , involves complete oxidation of glucose via cellular respiration
What are the two sources of oxygen for muscle tissue ?
diffusion from blood and release by myoglobin inside muscle fibers
aerobic system
will provide ATP for prolonged activty so long as sufficient oxygen and nutrients are available
Muscle Fatigue
the inability of a muscle to maintain its strngth of contration or tension , occurs when a mucls cannot produce enough ATP to meet its needs
Recovery Oxygen Uptake
elevated oxygen use after exercise
myoglobin
an oxygen reddish pigment
Red muscle fibers
have high myoglobin content
White muscle fibers
is low myoglobin content
Slow oxidative Fibers
smallest in diameter and therefore least powerful, large amounts of myoglobin and many blood capillaries generate ATP by aerobic cell respiration
Fast Oxidative-Glycolytic Fibers
are intermediate in diameter between the other two types, large amounts of myoglobin and many blood capillaries generate ATP by aerobic cellular respiration
Fast Glycolitic Fibers
are the largest in diameter and contain the most myofibrils, low myoglobin, and few blood capillaries , but contain large amounts of glycogen and generate ATP by glycolysis
What are skeletal muscle fibers classifed as ?
slow oxidative . fast oxidative-glycollytic, fast glycolytic
Where is cardiac muscle tissue found ?
Heart
Where is smooth muscle tissue found ?
in the hollow internal structures
When do muscle fibers contract?
when stimulated by their own autorhythmic fibers
Major physiological difference between cardiac and skeletal muscle tissue ?
autorhythmic continous fibers
Visceral (single unit) smooth muscle
found in the walls of hollow viscera and small blood vessels; the fibers are arranged in a network
Multiunit smooth muscle
found in large blood vessels, large airways, arrector pili muscles, and the iris of the eye. the fibers operate singly rather tha as a unit