Analgesic, Antipyreticm Anti-Inflammatory Drugs

Front 1

This drug is the prototype, most common used salicylate, effective for mild to moderate pain, skin, muscles, joints, inflammation,mild forms of arthritis, onset is 15-30 min, peaks @ 1-2 hrs, duration is 4-6 hrsm and half life is 15-20 min, food slows absorption and decreased GI upset.

Back 1

Aspirin

Front 2

These drugs are used to treat and prevent mild to moderate pain associated w. musculoskeletal disorders, headache, minor trauma and other acute disorders?

Back 2

Aspirin, NSAIDS and acetaminophen

Front 3

Aspirin is contraindicated in?

Back 3

In children and adolscents it is not used in the presence of viral infections (flu,chicken pox) because it is associated w/ Reye's syndrome

Front 4

A COX-2 inhibitor is?

Back 4

celecoxib(Celebrex)

Front 5

Celebrex is contraindicated in pts w/?

Back 5

PU (peptic ULcers)

Front 6

Propionic acid derivatives include?

Back 6

fenoprofen, flurbiprofen (ansaid), iboprofen, (motrin, advil), ketoprofen (oruvail), naproxen (Naprosyn)and oxaprozin (Daypro)

Front 7

Nsaid that has anti-inflamm actio that starts in about 30 min, & last 4-6 hrs

Back 7

Ibuprofen(motrin, adcil..etc)

Front 8

Acetic acid derivatives that have stron anti-infamm effects and more severe adverse effects than propionic acid derivatives?

Back 8

indomethacin(Indocin), sulindac(Clinoril), tolmetin(Tolectin)

Front 9

These adverse effects are associated with? GI ulceration, Bone marrow depression, Hemolytic anemia, mental confusion, psychosis?

Back 9

acetic acid derivatives

Front 10

This drug given by IV is approved for rx of patent ductus arteriosus in preemies?

Back 10

Indocin(indomethacin)

Front 11

This drug is the prototype, most common used salicylate, effective for mild to moderate pain, skin, muscles, joints, inflammation,mild forms of arthritis, onset is 15-30 min, peaks @ 1-2 hrs, duration is 4-6 hrsm and half life is 15-20 min, food slows absorption and decreased GI upset.

Back 11

Aspirin

Front 12

These drugs are used to treat and prevent mild to moderate pain associated w. musculoskeletal disorders, headache, minor trauma and other acute disorders?

Back 12

Aspirin, NSAIDS and acetaminophen

Front 13

Aspirin is contraindicated in?

Back 13

In children and adolscents it is not used in the presence of viral infections (flu,chicken pox) because it is associated w/ Reye's syndrome

Front 14

A COX-2 inhibitor is?

Back 14

celecoxib(Celebrex)

Front 15

Celebrex is contraindicated in pts w/?

Back 15

PU (peptic ULcers)

Front 16

Propionic acid derivatives include?

Back 16

fenoprofen, flurbiprofen (ansaid), iboprofen, (motrin, advil), ketoprofen (oruvail), naproxen (Naprosyn)and oxaprozin (Daypro)

Front 17

Nsaid that has anti-inflamm actio that starts in about 30 min, & last 4-6 hrs

Back 17

Ibuprofen(motrin, adcil..etc)

Front 18

Acetic acid derivatives that have stron anti-infamm effects and more severe adverse effects than propionic acid derivatives?

Back 18

indomethacin(Indocin), sulindac(Clinoril), tolmetin(Tolectin)

Front 19

These adverse effects are associated with? GI ulceration, Bone marrow depression, Hemolytic anemia, mental confusion, psychosis?

Back 19

acetic acid derivatives

Front 20

This drug given by IV is approved for rx of patent ductus arteriosus in preemies?

Back 20

Indocin(indomethacin)

Front 21

This drug causes less GI irritation? Used for OA,RA, and pain?

Back 21

etodolac(Lodine)

Front 22

This drig is used only for pain, and although it can be given orally, its unique characteristic is that it can be given by injection, but use is limited to 5days due to increased risk for bleeding?

Back 22

ketorolac(Totadol)

Front 23

This drug is used for moderate pain and dysmenorrhea?

Back 23

mefenamic acid (Ponstel) belongs to a family of NSAIDS called fenamates

Front 24

These drugs are containdicated in the presence of PU disease, GI or other bleeding disorders, history of hypersensitivity reactions, and impaired renal function

Back 24

aspirin and nonselective NSAIDs

Front 25

This drug is contraindicated in clients @ risk for excessive bleeding......shouldn't be used in Labor and delivery, b-4 or after maijor surgery or to clients who are currently taking aspirin or other NSAIDs?

Back 25

ketorolac(Toradol)

Front 26

A COX-2 inhibitor that is contraindicated for clients with a history of PU, GI bleeding, allergy to other NSAIDS or severe renal impairment and are allergic to sulfonamides?

Back 26

celecoxib(Celebrex)

Front 27

These drugs block prostaglandin production, produce less GI irration than ASA or NSAIDs, don't have antiplatelet effects?

Back 27

Cox-2 Inhibitors

Front 28

Drugs used for Gout?

Back 28

indomethacin(Indocin), naproxen sodium (Aleve, Anaprox, Napreian) sulindac (Chinoril) allopurinol(Zyloprim) Colchicine, probenecid (Benemid), sulfinpyrazone (Anturane)

Front 29

This drug is also knowna s APAP, nonpresp, ASA substitute that soesn't cause GI bleeding, interfere w/ blood coagulation, onset is 30-120 min and lasts 3-4 hrs?

Back 29

Acetaminophen

Front 30

What is an anti-inflam drug used to prevent acute attacks of gout and is the drug of choice for acute attacks,& relieves joint pain and edema ?

Back 30

colchicine

Front 31

This drug increases urinary excretion of uric acid and isn't effective in acute attacks of gouty arthritis, it's ised for therapeutic prevention of hyperurecemia & gout, but prevents hyperuricemia and tophi, is used w/ penicillin, most often in rx of stds?

Back 31

probenecid (Benemid)

Front 32

These drugsare used in rx of mod. to severe migraines, they act on serotonin receptors to increase serotonin in the brain, relieve migraine by constriciting blood vessels?

Back 32

SS 5 -HT (Triptans)
almotriptan(Axert)
naratriptan(Amerge)
sumatriptan(Imitrex)
frovatriptan(Frova)
rizatriptan(Maxalt)
zolmtriptan(Zomig)

Front 33

Because of the SS 5-HT vasonconstricctive properties, they are contraindicated in?

Back 33

Clients w/ a history of angina pectoris, MI or uncontrolled hypertension

Front 34

Adverse effects of SS 5-HT?

Back 34

parathesias, n/v, dizziness, drowsiness

Front 35

These drugs are ergot preparations used only in rx of migraines and are most effective when given SC or ijhalation at onset of migraine and they are contraindicated in pregnancy, HTN, PVD CAD renal'hepatic impairment, severe infections?

Back 35

ergotamine tartarte (Ergomar), DHE-45, Ergomar and caffeine (Cafergot)

Front 36

Rx for overdose of acetominophen?

Back 36

Mucomyst (acetylcysteine)

Front 37

Mucomyst is most effective when given ?

Back 37

8-10 hrs of acttaminophen ingestion