Analgesia And Sedation Icu

Front 1

Opioids are the agents most frequently used for pain relief and mild sedation in the ICU (5,6,12). They are most effective …

Back 1

for relieving dull tonic pain, less effective for intermittent sharp pain, and relatively ineffective for neuropathic pain….

Front 2

Morphine is the most frequently used opioid in ICUs (12), but fentanyl may be preferred because

Back 2

it is faster acting, devoid of active metabolites, and less likely to decrease blood pressure….

Front 3

Morphine has several active metabolites that can accumulate in renal failure. One metabolite (morphine-3-glucuronide…

Back 3

…) can produce central nervous system excitation with myoclonus and seizures

Front 4

The PCA is…

Back 4

patient controlled anesthesia

Front 5

Opioids produce a centrally mediated, dose-dependent decrease in both

Back 5

respiratory rate and tidal volume

Front 6

Opioids are well known for their ability to depress

Back 6

bowel motility

Front 7

Meperidine (Demerol, Pethidine) is a popular opioid analgesic that can be an

Back 7

an excitatory neurotoxin in critically ill patients, Accumulation of normeperidine can produce central nervous system excitation with agitation, tremors, myoclonus, delirium, hallucinations, and tonic–clonic seizures

Front 8

meperidine and morphine are equivalent in their ability to promote spasm of the

Back 8

of Oddi and increased intrabiliary pressure

Front 9

meperidine continues to be the preferred agent for control of

Back 9

…shivering

Front 10

Of the 13 benzodiazepines available for clinical use what 3 can be given IV?

Back 10

midazolam (versed), Ativan (lorazepam, valium (diazepam

Front 11

benzodiazepine of choice for short-term sedation

Back 11

versed (midazolam

Front 12

has the slowest onset of action of the intravenous benzodiazepines

Back 12

…(ativan) Lorazepam

Front 13

Intravenous preparations of lorazepam and diazepam contain the solvent

Back 13

propylene glycol

Front 14

longed administration of propylene glycol can cause?

Back 14

… paradoxical agitation, metabolic acidosis, and a clinical syndrome
P.897

that mimics severe sepsis

Front 15

For patients maintained for several days on a midazolam infusion, transitioning to what 1 day prior to extubation can decrease withdrawal?

Back 15

prpofol

Front 16

Propofol can be useful in neurologic injury because it ?

Back 16

reduces cerebral oxygen consumption and intracranial pressure

Front 17

Propofol Infusion Syndrome?

Back 17

… is a rare and often lethal idiosyncratic reaction characterized by the abrupt onset of heart failure, bradycardia, lactic acidosis, hyperlipidemia, and rhabdomyolysis

Front 18

The most feared adverse effects of haloperidol?

Back 18

NMS and TDP…