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87 Cards in this Set

  • Front
  • Back
What does the hypothalmus do?
secretes stimulating and inhibiting hormones
controls the pituitary
operates on the principle of negative feedback
Where do 18% of all brain tumors arise from?
pituitary gland
What are some signs and symptoms of a pituitary tumor?
h/a, loss of peripheral vision, unstable temperature, neurological manifestations, emotional changes, hydrocephalus
What are the 3 most common hormones related to pituitary tumors?
growth, prolactin, ACTH
What might a person with excessive growth hormone have?
acromegaly
What are some diagnostic tests used to diagnose a pituitary tumor?
CT/MRI
visual fields (remember a s/s is loss of peripheral vision)
hormone levels (growth, prolactin, cortisol)
What does the anterior pituitary gland control?
growth, metabolic activity and sexual development through hormones
What is some treatment options for your pt. with a pituitary tumor?
radiation, drug therapy (bromocriptine), surgery
What type of surgery would be an option for your pt. with a pituitary tumor?
transphenoidal hypophysectomy
Your pt. has just had a transphenoidal hypophysectomy, what would be your greatest concern for this pt. postoperatively?
hormone replacement. esp. cortisol immediately post op. but also ADH and thyroid (TSH)
What is considered excessive urine output?
more than 200 ml/hr
How would you help your post op pituitary tumor pt. to prevent increased ICP?
Head of bed elevated 30 degrees, have them change positions slowly, discourage coughing, bending or straining
What happens if the ADH hormone is disturbed?
it effects the pts Na balance and the pt will void frequenty and could result in dehydration
What condition can result due to excess of the growth hormone?
gigantism: before puberty

acromegaly: after puberty
How would you treat a pt. with acromegaly?
surgically, with radiation and with medication
What causes acromegaly?
a tumor in adults between 30-50
What can cause hyperprolactinemia?
tumors and drugs(BCP, aldomet, opiates, phenothiazines)
What are s/s of hyperprolactinemia?
galactorrhea, decreased libido, erectile dysfunction, menstrual irregularity, decreased visual fields
What does bromocriptine do?
med that inhibits prolactin secretion
What is diabetes insipidus?
deficiency of ADH (anti-diuretic hormone)
Explain what happens when you have a deficiency of ADH
the kidney are unable to concentrate urine, water is not reabsorbed by the kidneys. Pt has continuous excretion of large volumes of dilute urine, only water is excreted, not electrolytes.
What can result due to a deficiency of ADH?
hypovolemia, hypernatremia
What are some things that can cause the body to have a deficit of ADH?
cranial surgery, head trauma, brain tumors, infection of the CNS, drugs/alcohol, renal disease, can be idiopathic
What are some s/s your pt. might experience if they have a deficiency of ADH?
polyuria, thirst, signs of dehydration, nocturia, polydipsia, weight loss, incr. serum NA, neuro changes, cardiac, hypotension, tachycardia
If your pt. had diabetes insipidus, what would their BP and pulse be like and why?
decr. BP and incr. pulse due to dehydration
What test is given to diagnose diabetes insipidus?
water deprivation test (ADH is given SubQ and the urine is checked for concentration)
What types of treatment is there for your pt. with diabetes insipidus?
ADH replacement (dose must be titrated to symptoms)
What are some nursing implications for your pt. with diabetes insipidus?
fluids, strict I/O, weight checked daily, assess for s/s of dehydration and hypernatremia
What type of education would you give to your pt. with diabetes insipidus?
that they need to report incr. thirst, weight gain, nasal symptoms, edema, and they need to wear a medic alert bracelet
What is SIADH
syndrome of inappropriate ADH
Explain SIADH
ADH secretion occurs without regard to serum osmolality. This results in an incr. of ADH so the kidneys reabsorb water resulting in hypervolemia and hyponatremia
What are s/s of SIADH?
decr. LOC, irritability, anxiety, N/V, anorexia, oliguria, weight gain, seizures, coma, death
How do you diagnose SIADH?
check for a decr. serum sodium (hyponatremia) and a decr. serum osmolality
What is your treatment for ACUTE SIADH?
hypertonic saline (3%)
What is your treatment for CHRONIC SIADH?
fluid restriction, high sodium diet, demeclocycline, lasix
What is your goal in treating your SIADH pt.?
to return the NA level to normal slowly
What are your nursing concerns for your pt. with SIADH?
VS, weight, I/O, fluid restiction, neuro status, monitor labs (serum Na will be checked freq.)
What is hypothyroidism?
an insufficiency of the thyroid hormone
What is severe hypothyroidism called?
myexedema
What are s/s of hypothyroidism?
intolerant to cold, low temp, dry skin, thin hair, weight gain, decr. appetite, constipation, incr. interstitial fluid, incr. cholesterol, anemia, bradycardia, enlarged heart, hypotension, apathy, slow speech, lethargy, parasthesia
What diagnostic test would your do to diagnose hypothyroidism?
Check for elevated TSH, a decr. T3 and T4, presence of thyroid antibodies, CBC(anemia), high cholesterol, high TG
What is happening when a pt. has hypothyroidism?
everything slows down
Ex: ability to break down fats slows down resulting in weight gain
What medication might you put your pt on if they have hypothyroidism?
levothyroxine (synthroid)

*best absorbed if taken on an empty stomach, iron definitely interferes with absorption, slow process of feeling better, long 1/2 life
What is your pt at risk for if their hypothyroidism isnt corrected slowly?
fluid overload
What are some complications of hypothyroidism?
myexedema coma, hypothermia, hypotension, bradycardia, coma
What are some nursing concerns you might have for your hypothyroidism pt?
activity intolerance, nutrition, weight loss, impaired drug metabolism, temp instability, safety, elimination, respiratory depression, goiter, cardiac output
What education might you give to your hypothyroid pt.?
that improvement of symptoms is a slow progression and that they need to be aware of the signs of hyperthyroidism
What is hyperthyroidism?
chronic excess of thyroid hormone, f>M, autoimmune, inherited tendency
What are s/s of hyperthyroidism?
goiter (maybe), incr. body temp, intolerant to heat, incr. appetite, weight loss, weakness, diarrhea, decr.TG, tachycardia, incr. BP, CHF, A-fib, DOE, CP, nervous, restless, insomnia, tremors, osteoporosis, exophthalmos, altered reproductive function
What diagnostic findings should you look for if you suspect your pt. has hyperthyroidism?
decr. TSH, elevated T3 and T4, thyroid antibodies
What test would you use to help diagnose hyperthyroidism?
ultrasound, thyroid scan
What is the treatment of choice for hyperthyroidism?
radioactive iodine therapy - concentrates in the glands and decr. functioning, effects in 3 weeks but may take approx. 6 months to get to normal
What can happen if your hyperthyroid pt is radiated too much during therapy?
they can become hypothyroid
When would we consider removing the thyroid?
only if cancerous, sometimes if goiter or if it is effecting the pts airway
What are the medications for hyperthyroidism?
thioamides(suppresses thyroid function
Lugol's solution(decr. vascularity of the gland)
Beta Blockers (decr. symptoms)
When would you NOT give your hyperthyroidism pt a beta blocker?
when they are asthmatic, have COPD, or are diabetic
Why would you want your pts. euthyroid state to be restored before going to surgery?
to prevent thyroid storm (all hormones in gland are released in excess during surgery)
What are some complications of thyroid surgery?
damage to laryngeal nerve, hypoparathyroidism
What would be some signs of a calcium deficiency in your post op thyroid pt.? how would you treat it?
tingling around outh, toes, fingers, low serum Ca

treated with calcium gluconate
What type of diet would you place your post op thyroid pt. on?
high protein, high calorie
What is hypoparathyroidism?
decr. parathyroid hormone (low calcium level)
What can happen as a result of hypoparathyroidism?
since it is a low calcium level your pt. could experience tetny, laryngospasms, seizures, EKG changes
How would you diagnose hypoparathyroidism?
check for a decr. serum calcium level and a serum PTH level
How is hypoparathyroidism treated?
IV calcium gluconate, PO therapy
What is hyperparathyroidism usually caused by?
a tumor
What can happen as a result of hyperparathyroidism?
since it is a high calcium level your pt could experience hypercalcemia, osteoporosis, kidney stones, PUD
What is the treatment for hyperparathyroidism?
surgery, clacitonin, phosphates, loop diuretics, hydration
What is Addisons disease?
hyposecretion of cortisol and aldosterone
what does aldosterone regulate?
Na/H2O balance
what does cortisol regulate?
blood glucose levels
What can your pt. experience if they have a cortisol deficiency?
incr. ACTH(adrenocorticotropic hormone) and melanocytes, addisonian tan, hypoglycemia
Addison's disease is a deficiency in......
cortisol and aldosterone
Cortisol deficiency can cause?
addisonian tan, hypogylcemia
Aldosterone deficiency(mineralcorticoids) can cause?
kidney being unable to retain Na and excrete K, water goes with sodium, dehydration, hyponatremia, hyperkalemia
Waht are s/s of addisons disease?
hyoptension, tachycardia, decreased CO, dehydration, cardiac arrythmias, N/V, Hiarrhea, anorexia, weakness, fatique, emotional instability, hypoglycemia, pigmentation changes (addisons tan)
How would you diagnose addisons disease?
low cortisol levels, high ACTH, ACTH stimulation test, check for presence of auto-antibodies against 21-hydroxylase
What is the treatment for addisons disease?
a lifetime treatment of replacement. - hydrocortisone, incr. sodium intake or florinef(if prev. doesn't work)
What is addisonian crisis?
triggered by stress
life threatening hypotension, hyponatremia, hyperkalemia, dehydration
How is addisonian crisis treated?
IV steroid replacement, nl saline, glucose, electrolytes
What causes an addisonian tan?
increased melanocytes
What is cushings disease and what causes it?
long term excessive levels of cortisol
caused by a tumor (ACTH secreting or adrenal)
What systems does cushing disease effect?
CV, immune, MS, skin, endocrine, renal, hematology, psychological status
what are some s/s of cushings disease?
hypertension, edema, weight gain, dysrhythmias, DVT, infection, acne, etc
*remember: it effects multi systems
How do you diagnose cushings disease?
increased cortisol, decreased ACTH, dexamethasone suppression test, 24 hour urine
What are some nursing concerns with cushings disease?
fluid excess (VS, I/O, weights), electrolyte imbalance, diabetic care, vutrition (high protein, low sodium, high K, high Calcium), tissue perfusion (DVT), infection, skin care, activity intolerance
What is pheochromocytoma?
tumor of the adrenal medulla with secretes epi/norepi
What are the s/s of pheopchromocytoma and how is it treated?
severe hypertension not responsive to meds
Treated by removing the tumor and controlling BP