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22 Cards in this Set

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What a.a. is the smallest?
Glycine
What a.a. is involved in gluconeogenesis?
Alanine
What a.a. are branched?
Valine
Leucine
Isoleucine

I Saw Lucy and Val(erie) Like syrup
What a.a. bends proteins?
Proline
What a.a. is converted to tyrosine?
Phenylalanine
What is made with Tyrosine? 3 things...
1) Catecholamines (NE, Epi)
2) Thyroid T3/T4
3) Melanin
What causes Hartnup Dz?
Tryptophan

tryp up the esophagus
What coenzyme is needed to degrade tryptophan?
Niacin
What deffect do you see when you have Niacin defiency?
Pellagra
What are the symptoms of pellagra?
Diarrhea
Dermatitis
Dementia
What are the basic a.a.?
HAL

Histidine
Alaline
Lysine
What two a.a. are acidic?
Aspartate
Glutamate

aspartic acid, glutamic acid
What a.a. have OH in htem?
Serine
Threonine
Valine is a branched a.a. what happens glutamate is changed to val?

glutamate ----> valine
Sickle Cell Anemia

Missense mutation
anemia sickle
What happens when there is a deletion of phenylalanine at position 508?
Cystic Fibrosis

Chromosome seven
problem in folding proteins
Why is cysteine important?
Because it produces S-thiol and is the Tx for Acetaminophen Toxicity

NO+ guanylate cyclase increasing cGMP
Why is methionine important?
Makes AUG, SAM

initiate transcription
methylates in SAM
WHat is asparagine famous for?
N.glycosylation in E.R. mannose to protein
WHat is glutamine used for?
NH3 donor

Amonia
WHat a.a. is need in positve nitrogen balance?
Arginine
When does positive nitrogen balance occur?
Growth
Pregnancy
Recovery from injury or surgery
Recovery from Negative Nitrogen Balance
When does negative nitrogen balance?
Protein Malnutrition (Kwashiorkor)
Starvation (Marasmus)
DM uncontrolled
Infection
Diet Defficient of essential a.a.