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3 Cards in this Set

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  • Back
ALSr
Rapidly progressive, invariably fatal degeneration of nerves controlling voluntary muscles. Replacment of motor neurons with fibrous tissues causes hardening of anterior and lateral columns of the spinal cord, thus " lateral sclerosis"
Clinical Manifestations of ALS
Twitching, cramping, and muscle weakness
Dysarthria and dysphagia
Fatigue; asymmetrical muscle atrophy and weakness
Most often fatal witin 2 to 5 years after onset
Dx of ALS
electromyography, and nerve conduction studies. Muscle biopsy may be preformed to rule out other pathologies.