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11 Cards in this Set
- Front
- Back
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tx parkinson's
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Methydopa
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OH conjugation
decarboxylates hydroxylates |
methydopa
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reaction occurs stereoselective
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methydopa-it is hydroxylated only at one place and you get only 1 product (1R,2S) overall levo activity
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better absorbed as a prodrug
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methydopate
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hydrolyzed in blood delayed
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methydopate
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duration is long
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methydopate
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generates no active metabolites
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Reserpine
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acts by indirect mechanism
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Guanethedine
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oxidative-deamination process
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Guanethedine
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metabolite is 10% as active as parent
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Guanethedine
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greater GI absorption than Guanethidine
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Guanedrel
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