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6 Cards in this Set
- Front
- Back
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What is an allergy
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Allergies are abnormal sensitivities to antigens in the environment
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what is a allergen
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antigens that cause allergies
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Sensitization- first exposure to allergen
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1) Tissue contact with allergen (antigen)
2) B cells produce IgE against allergen 3) IgE attaches to mast cells |
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Reaction- second exposure to allergen
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1) Allergens complex with IgE on mast cells
2) Mast cells release histamine and other chemicals 3) Blood vessels dialate and release plasma |
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what causes Anaphylactic Shock
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degranulation of many mast cells at once causes the release of large amounts of histamine and inflammatory mediators
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What is The Hygiene Hypothesis
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A hypothesis that states that exposure to allergens in the environment early in life reduces the risk of developing allergies by boosting immune system activity.
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