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17 Cards in this Set
- Front
- Back
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histamine receptors?
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1: broncoconstrict, contract vasculature, peripheral sensory nerve stim
2: increase HR and gastric acid secretion 3: CNS neuro trans |
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pharm tx for allergic rhinitis?
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antihistamines, nasal decongestant, intranasal corticosteroids, mast cell stabalizer, intranasal anticholinergics, leukotriene antagonist
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1st gen antihistamines that have high anticholinergic effect?
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benadryl and phenagran, also sedatives
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when are 1st gen recommmended in allergic rhinitis?
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they are not recommended
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2nd gen drugs?
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zyrtec, clarinex, allegra, claritin
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1st line tx for mild-mod allergic rhinitis?
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2nd gen drugs
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side effects of 2nd gen drugs?
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anti-salivation, lacrimation, urination, defaction
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topical antihistamine?
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azelastine
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nasal decogestants?
systemic? |
phenylephrine, tetrahydrolozine, afrin
sudafed |
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side effects of systemic nasal decongestant?
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cns stim, increase BP and HR, contraindicated with MAOI
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most effective drugs available for prevention and tx of mod-severe allergic rhinitis?
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intranasal corticosteroids (nasocort, beconase, flonase, rhinocort)
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onset of intranasla corticosterids?
adverse effects? |
a few days, peak effects may be in a few weeks
sneezing headache epistaxis candida sinusitis |
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what can be used as a prophylactic to allergic rhinitis?
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mast cell stabalizer (cromolyn)
start 2-4 weeks prior to exposure |
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Intranasal anticholinergic should be used for?
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nasal discharge. no relief of sneezing, itching, nasal decongest
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who should you use the above on?
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ppl with glaucoma
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leukotriene antagonist?
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blocks inflammatory mediators. as effective as 2nd gen antihistamines, good adjuvent therapy
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what can you give people with allergic conjunctivitis?
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itching relieved by H1 antihistamines
topical decongestant can relieve swelling and congestion |
