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7 Cards in this Set

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  • Back

What kind of neurotransmitter is acetylcholine?

Amine

Acetylcholine is synthesized by...

Choline Acetyltransferase (ChAT)


Acetyl CoA + Choline -> ACh

Acetylcholine is broken down by...

Reputake


Acetylcholinesterase


ACh -> acetic acid + choline

Function of acetylcholine

Muscle activation, arousal, attention, motivation

Where is acetylcholine found?

Primarily in the neuromuscular junctions of all motor neurons

Acetylcholine's ionotropic receptor(s)

Nicotinic receptors (nAChR)


Moves Na+ and K+


5 subunits (2alpha and 3 others)


ACh must bind to both alpha units for receptor activation

Acetylcholine's metabotropic receptor(s)

Muscarinic receptors


Fall under metabotropic class Gq and Gi/o