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6 Cards in this Set
- Front
- Back
ALBUTEROL
class/ MOA |
Class
Sympathomimetic, bronchodilator. Mechanism of Action Selective b-2 agonist which stimulates adrenergic receptors of the sympathomimetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature. |
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ALBUTEROL
I/CI |
Indications
Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD/asthma). Prevention of exercise-induced bronchospasm. Contraindications Known prior hypersensitivity reactions to Albuterol. Tachycardia dysrhythmias, especially those caused by digitalis. Synergistic with other sympathomimetics |
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ALBUTEROL
DI/AR |
Adverse Reactions
Often dose-related and include restlessness, tremors, dizziness, palpitations, tachycardia, nervousness, peripheral vasodilatation, nausea, vomiting, hyperglycemia, increased blood pressure and paradoxical bronchospasm Drug Interactions Tricyclic antidepressants may potentate vasculature effects. Beta-blockers are antagonistic. May potentate hypokalemia caused by diuretics. |
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ALBUTEROL
How Supplied |
How Supplied
Solution for aerosolization: 0.5% (5 mg/ml) Metered Dose Inhaler: 90 mcg/metered spray (17 gm canister with 200 inhalations) Syrup: 2 mg/5 ml |
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ALBUTEROL
Doseage/ adiminisration |
Dosage and Administration
Adult: Administer 2.5 mg. Dilute 0.5 ml of 0.5% solution for inhalation with 2.5 ml normal saline in nebulizer and administer over 10-15 minutes. MDI: 1-2 inhalations (90-180 mcg). Five minutes between inhalations Pediatric: Administer solution of 0.01 - 0.03 ml (0.05 - 0.15 mg/kg/ dose diluted in 2 ml of 0.9% Normal Saline. May repeat every 20 minutes three times. |
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ALBUTEROL
DOA/ Specials |
Duration of Action
Onset in 5-15 minutes with peak effect in 30-minutes - two hours and duration of 3-4 hours. Special Considerations Pregnancy Safety: Category C. Antagonized by beta-blockers (e.g., Inderal, Metoprolol ) May precipitate angina pectoris and dysrhythmias. Should only be administered by inhalation methodology in pre-hospital management. |