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47 Cards in this Set

  • Front
  • Back

How often are our bodies creating waste?

Constantly

Our bodies release CO2 as a waste from __________

cell resp

The ____ breaks down wastes from alcohol and other poisons, as well as waste from protein breakdown.


Then, what happens?

liver


The wastes then go to the kidneys to be eliminated from the blood.

Kidney roles

Remove protein waste


Balance blood pH


Maintain the body's water balance.

1% drop in fluid will cause _______


5% drop in fluid will cause _______


10% drop in fluid will cause _______

thirst


pain


death

Why must the body get rid of nitrogen when converting protein into carbohydrate?



Because the protein contains nitrogen and carbohydrates don't.

Deamination define


what is the byproduct?


why is that a problem?


what is the solution? why?

Breakdown of protein by the liver


ammonia


ammonia is very toxic to our bodies.


the solution is to very quickly react the ammonia with carbon dioxide to make urea. Urea is 100,000 times less toxic than ammonia

When nucleic acids are broken down, what is a waste product?


Example of nucleic acid.

uric acid is the waste product


DNA

If uric acid was to build up in your body, what would happen?

it would cause a disorder called gout which causes painful swellings.

Renal arteries branch off the _____ to carry ____ to the _____.

aorta


blood


kidneys

the kidneys can hold as much as _____ OF THE BODY'S BLOOD

25%

_____ leave the kidneys to return to the heart

renal veins

once wastes are filtered in the _____, they enter the _____.

kidneys


ureter

the wastes are stored in the _____

bladder

where is the urinary sphincter muscle located?


what's its role?

at the bottom of the bladder


allows for control

at what point does your brain get the message that you need to go?

at 200 ml

at what point is the msg urgent?

at 400 ml

at what point is voluntary control lost?

at 600 ml

3 layers to the kidney? explain each

an outer layer called the cortex


an inner layer called the medulla


an empty chamber called the renal pelvis

_____ are the functional unit of the kidney.

nephrons

what leads to the nephrons


then?


then?


when does it become a vein

afferent arterioles


they branch into a capillary bed called the glomerulus


the blood then leaves the capillary bed through the efferent arteriole


when reabsorption is done

peritubular capillaries

small capillaries that wrap around the kidney tubules

what is done in the nephron?


what is done after this process?

reabsorption


the capillaries then join together to male venules that lead into the renal vein.

surrounding the glomerulus is: ____


what exits the glomerulus into the ___?

bowman's capsule


fluid (with dissolved substances)


bowman's capsule

bowman's capsule leads to _____


the distal tubule leads into the _____

-downwards to become the proximal tubule which then becomes the loop of henle and then travels upwards as the distal tubule


-collecting duct

3 steps of urine filtration? explain

filtration (of blood fluid into Bowman's capsule)


reabsorption (of essential substances back into the blood)


secretion (of other excess materials from blood into filtrate)

Explain the first step of urine formation:_____

-Filtration


-Normal capillary blood pressure is 25 mm Hg, but in the glomerulus, it increases to 65 mm Hg.


-This extra pressure pushes fluid and dissolved substances out of the capillary and into the Bowman's capsule


-Large molecules will not move through

Explain the second step of urine formation:_____

-Reabsorption


-About 600mL of fluid passes through the kindney each minute


-Of this, about 120 mL passes out into the glomerulus


-A chemical called aldosterone causes the body to reabsorb Na+ ions and water


-As Na+ ions are actively transported in, other ions like Cl- and HCO3- passively follow due to charge attraction


-After a certain thereshold amount is reached, any excess sodium is passed out with the urine.


-Other molecules like glucose are also actively transported out of the nephron to be reabsorbed by the blood.

Substance transported


Direction transported


Active or passive



HCO3-


NaCl


H+


H2O


NH3


Nutrients


K+

Out of the tubule


passive



Out of the tubule


active



Into the tubule


Active



Out of the tubule


Passive



Into the tubule


Passive



Out of the tubule


Active



Out of the tubule


Passive

In the descending loop of Henle, ____ Is transported out.

water

What blood vessel enters the kidney?

Renal artery

what blood vessel does filtration occur in?

Glomerulus

What blood vessel does secretion occur in?

PCT

Where does reabsorption take place?

PCT


stuff in filtrate differs from stuff in blood by _____

size

Where are the salt and water in the nephron?

Everywhere

What process happens from glomerulus to Bowman's capsule?

Filtration of filtrate

active transport

movement of substances across cell membranes against a concentration gradient which uses energy.

process that pulls salt from pct?


water from pct?

active


passive

common diuretics?


diuretics meaning?

alcohol, coffee, tea (anything with coffee)


any substance that promotes the production of urine


Explain the 3rd step of urine production: ________


examples of materials that this is done to

secretion


the forced movement of other wastes into the nephron


ammonia, excess pottasium, and drugs.

ADH:


secreted by:


effect on ____:

secreted by pituitary gland in the brain


makes collecting duct more permable to water

Aldosterone:


secreted by:


effect on ___:


water...

secreted by adrenal cortex


causes Na+ to be reabsorbed


Water follows osmotically

Diabetes Mellitus:


caused by?


explain?


side effect?

-caused by lack of insulin


-the body does not store the glucose so it is secreted out with the urine


-people with diabetes make large amounts of urine and as a result are often thirsty

Diabetes Insipidis:


also called?


caused by?


explain?


result?

-also called water diabetes


-caused by too little antiduretic hormone


as a result they don't reabsorb the water from -----the filtrate


-the result is a large amount of dilute urine

kidney stones:


explain

solidification of minerals, often calcium oxalate


are sharp and painful


can become lodged

how to treat kidney stones

broken down with high energy shockwave instead of surgically removing them like they used to and therefore are less painful to pass.