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214 Cards in this Set

  • Front
  • Back
Stage I Rectal Adenocarcinoma
T1 N0 or T2 N0.
Stage II rectal adenocarcinoma
IIA. T3 N0 M0
IIB. T4a N0 M0
IIIC. T4b N0 M0
Stage IV rectal adenocarcinoma
IVA. M1a
IVB. M1b
T1 rectal adenocarcinoma
Tumor invades submucosa of rectum
T2 rectal adenocarcinoma
Tumor Invades muscularis propria
T3 rectal adenocarcinoma
Tumor invades through muscularis propria and into pericolorectal tissues
T4 rectal adenocarcinoma
T4a. tumor penetrates surface of visceral peritoneum
T4b. tumor directly invades or is adherent to other organs( e.g. prostate, seminal vesicles, cervix, vagina)
Tis rectal adenocarcinoma
Carcinoma in situ, intraepithelial or invasion of lamina propria.
N2b rectal adenocarcinoma
metastasis to 7 or more regional lymph nodes
N2a rectal adenocarcinoma
metastasis to 4-6 regional lymph nodes
N1c rectal adenocarcinoma
tumor deposits in the subserosa, mesentery, or non-peritonealized pericolic or perirectal tissues without nodal metastasis
N1b rectal adenocarcinoma
Metastasis to 2-3 regional lymph nodes
N1a rectal adenocarcinoma
Metastasis to 1 regional lymph nodes
M1a rectal adenocarcinoma
Metastasis to one organ or site, (e.g. liver, lung, ovary, non-regional node)
M1b rectal adenocarcinoma
Metastasis to more than one organ/site or the peritoneum
Stage IIIA rectal adenocarcinoma
T1-2 N1, or T1 N2a
Stage IIIC rectal adenocarcinoma
T4a N2a
T3-4a N2b
T4b N1-2
Stage IIIB rectal adenocarcinoma
T3-4a N1
T2-3 N2a
T1-2 N2b
Stage III rectal adenocarcinoma breakdown
IIIA
IIIB
IIIC
T1 glottic cancer
T1a. tumor limited to 1 true vocal cord
T1b. tumor involves both vocal cords

*tumor may involve anterior or posterior commisure
T2 glottic cancer
tumor extends to supraglottis or subglottis
tumor impairs vocal cord mobility
Stage III cervix cancer breakdown
Stage IIIA
Stage IIIB
Stage IIIB cervix cancer
Tumor extends to pelvic sidewall
Causes hydronephrosis or nonfunctioning kidney
Regional lymph node metastasis
Stage IIIA cervix cancer
Tumor involves lower third of the vagina
Stage IIB cervix cancer
Tumor with parametrial involvement
Stage IIA cervix cancer
Tumor extending beyond cervix, but no parametrial invasion

IIA1. Clinically visible lesion, but 4 cm or less in size

IIA2. Clinically visible lesion, > 4 cm in size
Stage IB cervix cancer
1B1. Tumor limited to cervical uterus, clinically visible but 4 cm or less in size

1B2. Tumor limited to cervical uterus, clinically visible and > 4 cm
Stage IA cervix cancer
1A1.clinically not visible lesion, measures stromal invasion 3.0 mm or less and 7.0 mm or less in horizontal spread

1A2. Measured stromal invasion more than 3.0 mm and not more than 5.0, horizontal spread 7.0 mm or less
Stage IVA cervix cancer
Tumor invades mucosa of bladder or rectum, and or extends beyond true pelvis
Stage IVB cervix cancer
Distant metastasis including peritoneal spread, supraclavicular, mediastinal, paraaortic lymph nodes, lung liver or bone
T3 prostatic adenocarcinoma
T3a. Extracapsular extension
T3b. tumor invades into seminal vesicles.
Stage I Nasopharynx cancer
T1 N0
Stage II Nasopharynx cancer
T1 N1
T2 N1
T2 N0
Stage III Nasopharynx cancer
T1-3 N2
T3 N0
T3 N1
Stage IVA Nasopharynx cancer
T4 N0
T4 N1
T4 N2
Stage IVB Nasopharynx cancer
Any T, N3 M0
T1 Subglottic cancer
Tumor limited to subglottis
T2 Subglottic cancer
Tumor extends to vocal cords with normal or impaired mobility
T3 Subglottic cancer
Tumor limited to larynx with vocal cord fixation
T4a Subglottic cancer
Moderately advanced disease with disease invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g. trachea, soft tissues or the neck including extrinsic tongue muscles, strap muscles, thyroid, esophagus).
T4b Subglottic cancer
Very advanced disease, tumor invades prevertebral space, encases carotid, or invades mediastinal structures
T4b Supraglottic cancer
tumor invades prevertebral space, encases carotid artery or invades mediastinal structures
T4b Glottic cancer
tumor invades prevertebral space, encases carotid artery or invades mediastinal structures
T3 Supaglottic cancer
Tumor limited to larynx with vocal cord fixation and/or invading post cricoid area, preepiglottic space, paraglottic space, inner cortex of thyroid cartilage
T4a Glottic cancer
Tumor invades through thyroid cartilage, and or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, esophagus)
T4a Supraglottic cancer
Tumor invades through thyroid cartilage, and or invades tissues beyond the larynx (e.g., trachea, soft tissues of the neck including deep extrinsic muscles of the tongue, strap muscles, thyroid, esophagus)
N3 for larynx, hypopharynx, oropharynx, major salivary gland, nasal cavity or paranasal sinus
Nodal metastasis > 6 cm
N2c for larynx, hypopharynx, oropharynx, major salivary gland, nasal cavity or paranasal sinus
Nodal metastasis to bilateral or contralateral neck nodes, but none > 6 cm
N2a for larynx, hypopharynx, oropharynx, major salivary gland, nasal cavity or paranasal sinus
Nodal metastasis to a single node that is greater than 3 cm but 6 cm or less in size
N2b for larynx, hypopharynx, oropharynx, major salivary gland, nasal cavity or paranasal sinus
Nodal metastasis to multiple ipsilateral lymph nodes, none > 6 cm
N1 for larynx, hypopharynx, oropharynx, major salivary gland, nasal cavity or paranasal sinus
Nodal metastasis 3 cm or less in size
T4 Non-small cell lung cancer
Tumor of any size that invades any of the following structures: mediastinum, esophagus, vertebrae, heart, great vessels, trachea, recurrent laryngeal, carina, separate tumor nodule in ipsilateral but different lobe
T3 Non-small cell lung cancer
Tumor > 7 cm, or one that directly invades parietal pleura, chest wall, superior sulcus tumors, diaphragm, phrenic nerve, mediastinal pleura, parietal pericardium, mainstem bronchus within 2 cm of carina, associated atelectasis or obstructive pneumonitis of entire lung or separate tumor nodule in same lobe.
T2 Non-small cell lung cancer
T2a: Tumor more than 3 cm but 5 cm or less
T2b: Tumor more than 5 cm but 7 cm or less.

Can involve mainstem bronchus, 2 cm or more distal to carina. Invades visceral pleura, Associated with atelectasis that involves the hilar region but not the entire lung
N2 Non-small cell lung cancer
Nodal metastasis in ispilateral mediastinal and/or subcarinal lymph node
N3 Non-small cell lung cancer
Nodal metastasis to contralateral mediastinal or hilar, ipslateral or contralateral scalene or supaclavicular nodal disease
T1 Maxillary sinus cancer
Tumor restricted to maxillary sinus mucosa, no bone erosion
T3 Glottic carcinoma
Tumor limited to larynx with vocal cord fixation, invasion of paraglottic space, inner cortex of the thyroid cartilage
T2 prostate cancer (clinical)
palpable tumor

T2a - tumor involves 1/2 or less of one lobe
T2b - tumor involves > 1/2 of one lobe
T2c - tumor involves both lobes
T1c prostate cancer
Tumor identified by needle biopsy because of elevated PSA. This is tumor that is not palpable or visible by imaging.
T2 supraglottic cancer
tumor invades mucosa of more than one subsite of supaglottis, or region outside of the supraglottis (e.g. base of tongue, vallecula, medial wall of pyriform sinus) without fixation of the vocal cords
Stage IIB soft tissue sarcoma
T2a N0 G2
T2b N0 G2
Stage IB soft tissue sarcoma
T2a N0 G1, GX
T2b N0 G1, GX
Stage IA soft tissue sarcoma
T1a N0 G1, GX
T1b N0 G1, GX
Stage IIA soft tissue sarcoma
T1a N0 M0 G2,3
T1b N0 M0 G2,3
Stage III soft tissue sarcoma
T2a, T2b N0, G3
Any T, Any N M1
Stage IV soft tissue sarcoma
Any T Any N, M1
Stage II anal squamous cell carcinoma
T2 N0
T3 N0
Stage IIIA anal squamous cell carcinoma
T1-3 N1 M0
T4 N0
Stage IIIB anal squamous cell carcinoma
T4 N1
Any T, N2
Any T, N3
Stage IV anal squamous cell carcinoma
Any T Any N M1
Stage I anal squamous cell carcinoma
T1 N0
Stage III breakdown for anal squamous cell carcinoma
IIIA
IIIB
T1 anal squamous cell carcinoma
Tumor 2 cm or less in size
T2 anal squamous cell carcinoma
Tumor > 2 cm but 5 cm or less.
T3 anal squamous cell carcinoma
Tumor > 5 cm
T4 anal squamous cell carcinoma
Tumor of any size invading vagina, urethra, bladder
N3 anal squamous cell carcinoma
Metastasis to perirectal and inguinal nodes
Bilateral internal iliac nodes
Bilteral Inguinal nodes
N2 anal squamous cell carcnoma
Metastasis to unilateral internal iliac and/or inguinal lymph nodes
N1 anal squamous cell carcinoma
Metastasis to perirectal nodes
T3 hypopharynx cancer
Tumor more than 4 cm, esophageal extension, fixation of the hemilarynx
T1 hypopharynx cancer
Tumor 2 cm or less, and/or limited to one sub-site of hypophayrnx
pN2a Breast cancer
Metastasis to 4-9 axillary lymph nodes, macrometastasis in atleast one
pN2b Breast cancer
Clinically detected internal mammary nodes without axillary nodal metastasis
pN1b Breast cancer
Metastases in internal mammary nodes with micrometastasis or macrometastasis
pN1a Breast cancer
Metastasis to 1-3 axillary lymph nodes, with at least one being a macrometasis
pN1mi Breast cancer
Metastases > 0.2mm, and/or more than 200 cells but 2 mm or less in size
pN3c, Breast cancer
metastasis to ipsilateral supraclavicular nodes
pN3a, Breast cancer
metastasis to 10 or more axillary lymph node with atleast 1 deposit, > 2 mm or metastasis to Infraclavicular (level III node)
pN3b, Breast cancer
Clinically detected ipsilateral internal mammary, with 1 or more positive axillary nodes
Micrometastasis to internal mammary node with > 3 positive axillary macromets
T4a breast cancer
Invasion of the chest wall, excluding invasion of the pectoralis muscle only
T4b Breast cancer
Skin ulceration
Skin ipsilateral satellite nodules
Skin edema including peau d'orange of the skin, not meeting criteria for inflammatory carcinoma
T3 Breast cancer
Tumor > 5 cm
T2 Breast cancer
Tumor > 2 cm, but 5 cm or less
T1a Breast cancer
Tumor > 1 mm but 0.5 cm or less in size
T1b Breast cancer
Tumor > 0.5 cm, but 1cm or less in size
T1c Breast cancer
Tumor > 1 cm but 2 cm or less in size
T4c Breast cancer
Both T4a and T4b
T4d Breast Cancer
Inflammatory carcinoma
Inflammatory carcinoma of the breast
Diffuse malignant erythema and edema (peau d'orange) of the breast.
Tis (DCIS)
Ductal carcinoma in situ
Tis (LCIS)
Lobular carcinoma in situ
T1mi
Tumor 1mm or less in size,
clinical N1 Breast cancer
Metastases to ipsilateral axillary level I,II. Movable on exam.
clinical N2a Breast cancer
Metastases to ipsilateral axillary nodes Level I, II nodes, matted (fixed) to one another or other structures
clinical N2b Breast cancer
Clinically detected internal mammary nodes, clinically negative axilla
clinical N3a Breast cancer
Metastasis to ipsilateral infraclavicular nodes
Stage II Bladder Cancer
T2a N0
T2B N0
Stage I Bladder Cancer
T1 N0
N3 Bladder Cancer
Lymph node metastasis to common iliac nodes
T4a Bladder cancer
Invades adjacent organs (e.g., prostatic stroma, seminal vesicles, uterus)
T4b Bladder cancer
Tumor invades pelvic wall, abdominal wall
pT3a Bladder cancer
Tumor microscopically demonstrating perivesicular invasion
pT3b Bladder cancer
Tumor macroscopically demonstrating perivesicular invasion
Stage IV Bladder cancer
T4b N0
Any T N1-3
Any T Any N M1
Stage III Bladder Cancer
T3a N0
T3b N0
T4a N0
Stage II Bladder Cancer
T2a N0
T2b N0
Stage I Bladder Cancer
T1 N0
N3 Bladder Cancer
Lymph node metastasis to common iliac nodes
pT2a Bladder Cancer
Tumor invades inner half of the muscularis propria
T2 Nasopharynx
tumor with parapharyngeal extension
T3 Nasopharynx
tumor involves bony skull base or paranasal sinus
T4 Nasopharynx
Tumor with intracranial extension and/or involvement of cranial nerves, hypopharynx, orbit, extension into the infratemporal fossa/masticator space
T1 Nasopharynx
Tumor confined to nasopharynx or tumor extends to oropharynx and/or nasal cavity without parapharyngeal extension
N3b Nasopharynx
Extension of tumor to the supraclavicular fossa
N3a Nasopharynx cancer
Tumor Greater than 6 cm in size
Pancreatic cancer: T1
Tumor limited to pancreas, 2 cm or less in size
Pancreatic cancer: T2
tumor limited to pancreas, more than 2 cm in size
Pancreatic cancer: T3
Tumor extends beyond the pancreas but without involvement of the celiac axis or the SMA
Pancreatic cancer: T4
Tumor involves the celiac axis or the SMA
Pancreatic cancer: N1
Positive for regional lymph node disease
Pancreatic cancer: Stage IA
T1 N0
Pancreatic cancer: Stage IB
T2 N0
Pancreatic cancer: Stage IIA
T3 N0
Pancreatic cancer: Stage IIB
T1 N1
T2 N1
T3 N1
Pancreatic cancer: Stage III
T4 Any N
Pancreatic carcinoma: Stage IV
Any T, Any N, M1
Oral Cavity carcinoma: T1
Tumor 2 cm or less in size
Oral cavity carcinoma: T2
Tumor more than 2 cm but 4 cm or less in size
Oral cavity: T3
Tumor more than 4 cm in size
Oral cavity carcinoma: T4a
Tumor invades through cortical bone, inferior alveloar nerve, floor of mouth, skin of face, deep extrinsic muscles of tongue, maxillary sinus
Oral cavity carcinoma: T4b
Tumor invades masticator space, pterygoid plates, skull base, encase carotid artery
Oral Cavity Carcinoma: Stage I
T1 N0
Oral cavity carcinoma: Stage II
T2 N0
Oral cavity carcinoma: Stage III
T3 N0
T1 N1
T2 N1
T3 N1
Oral cavity carcinoma: Stage IVA
T4a N0
T4a N1
T1 N1
T2 N2
T3 N2
T4a N2
Oral Cavity carcinoma: Stage IVB
Any T, N3
T4b, Any N
Oral cavity carcinoma: Stage IVC
Any T, Any N, M1
Non-small cell lung cancer: Stage IA
T1a N0
T1b N0
Non-small cell lung cancer: Stage IB
T2a N0
Non-small cell lung cancer: Stage IIA
T2b N0
T1a N1
T1b N1
T2a N1
Non-small cell lung cancer: Stage IIB
T2b N1
T3 N0
Non-small cell lung cancer: Stage IIIA
T1a N2
T1b N2
T2a N2
T2b N2
T3 N1
T3 N2
T4 N0
T4 N1
Non-small cell lung cancer: Stage IIIB
T1a N3
T1b N3
T2a N3
T2b N3
T3 N3
T4 N3
T4 N2
Non-small cell lung cancer: Stage IV
Any T, Any N, M1a
Any T, Any N, M1b
Hypopharynx: T4a
Moderately advanced: invades thyroid or cricoid cartilage, hyoid bone, thyroid gland, central compartment soft tissue
Hypopharynx cancer: T2
Tumor invades more than one subsite of the hypopharynx and/measures more than 2 cm in size but 4 cm or less, without fixation of the hemilarynx
Hypopharynx cancer: T4a
Moderately advanced disease, tumor invades the thyroid or cricoid cartilage, hyoid bone, thyroid gland, or central compartment soft tissue.
Oropharynx cancer: T1
Tumor 2 cm or less in size
Oropharynx cancer: T2
Tumor more than 2 cm but 4 cm or less in size
Oropharynx cancer: T3
Tumor more than 4 cm in greatest dimension or extension on the lingual surface of the epiglottis
Oropharynx cancer: T4a
Moderately advanced disease, tumor invades the larynx, extrinsic muscles of the tongue, medial pterygoid, hard palate, mandible
Oropharynx cancer: T4b
Very advanced disease, tumor invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, skull base or encasement of the carotid artery
Nasopharynx cancer: N2
Bilateral metastasis on cervical LN, 6 cm or less in size
Nasopharynx cancer: N3b
Node within supraclavicular fossa
Nasopharynx cancer: N3a
Node greater than 6 cm in size
Nasopharynx cancer: N1
Unilateral metastasis in cervical LN, 6 cm or less in size, above the SCL fossa

Unilateral or bilateral retropharyngeal nodes, 6 cm or less in size
Oropharynx cancer: Stage I
T1 N0
Oropharynx cancer: Stage II
T2 N0
Oropharynx cancer: Stage III
T3 N0
T1 N1
T2 N1
T3 N1
Oropharynx cancer: Stage IVA
T4a N0
T4a N1
T1 N2
T2 N2
T3 N2
T4a N2
Oropharynx cancer: Stage IVB
T4b Any N
Any T N3
Oropharynx cancer: Stage IVC
Any T, Any N, M1
Hypopharynx cancer: I
T1 N0
Hypopharynx cancer: II
T2 N0
Hypopharynx cancer: III
T3 N0
T3 N1
T2 N1
T1 N1
Ampullary Cancer: T1
Tumor limited to ampulla of vater or sphincter of oddi
Ampullary Cancer: T2
Tumor invades duodenal wall
Ampullary Cancer: T3
Tumor invades pancreas
Ampullary Cancer: T4
Tumor invades peripancreatic soft tissues or other adjacent organs or structures
Ampullary Cancer: N1
Regional lymph node metastasis
Ampullary Cancer: Stage IA
T1 N0
Ampullary Cancer: Stage IIA
T3 N0
Ampullary Cancer: Stage IIB
T1 N1
T2 N1
T3 N1
Ampullary Cancer: Stage III
T4 Any N
Ampullary Cancer: Stage IV
Any T, Any N, M1
Ampullary Cancer: IB
T2 N0
Thyroid carcinoma: T3
Tumor > 4 cm in size but limited to thyroid, or any tumor with minimal extathyroidal extension (sternothyroid, perithyroid)
Thyroid carcinoma: T2
Tumor > 2 cm but 4 cm or less in size
Thyroid carcinoma: T1a
Tumor 1 cm or less in size, limited to thyroid
Thyroid carcinoma: T1b
Tumor more than 1 cm, but 2 cm or less and limited to thyroid
Renal cell carcinoma: T4
Tumor invades beyond gerota's fascia, including contiguous extension into the ipsilateral adrenal gland
Renal cell carcinoma: T3c
Tumor grossly extends into the vena cava above the diaphragm or invades the wall of the vena cava
Renal cell carcinoma: T3b
Tumor grossly extends into the vena cava below the level of the diaphragm
Renal cell carcinoma: T3a
Tumor extends grossly into the renal vein or its segmental branches or tumor invades perirenal and/or renal sinus fat but not beyond Gerota's fascia
Renal cell carcinoma: T2a
Tumor > 7 cm but 10 cm or less and limited to kidney
Renal cell carcinoma: T2b
Tumor greater than 10 cm but limited to kidney
Renal cell carcinoma: T1a
Tumor is 4 cm or less in size, limited to kidney
Renal cell carcinoma: T1b
Tumor is more than 4 cm but 7 cm or less in size
Renal cell carcinoma: N1
Metastasis in regional lymph nodes
Renal cell carcinoma: M1
Distant metastasis
Renal cell carcinoma: Stage I
T1 N0
Renal cell carcinoma: Stage II
T2 N0
Renal cell carcinoma: Stage IV
T4 N0
Any T Any N, M1
Renal cell carcinoma: Stage III
T1 N1
T2 N1
T3 N0
T3 N1
Non-small cell lung cancer: Stage IA
T1a N0
T1b N0
Non-small cell lung cancer: Stage IB
T2a N0
Non-small cell lung cancer: Stage IIA
T2b N)
T1a N1
T1b N1
T2a N1
Non-small cell lung cancer: Stage IIB
T2b N1
T3 N0
Non-small cell lung cancer: Stage IIIA
T1-3 N2
T3 N1
T4 N0
T4 N1
Non-small cell lung cancer: Stage IIIA
T4 N2
T1-T4 N3
Non-small cell lung cancer: Stage IV
Any T Any N, M1a or M1b
Non-small cell lung cancer: T1a
Tumor < 2 cm, no visceral pleura invasion, no MSB invasion
Non-small cell lung cancer: T1b
Tumor > 2 cm but 3 cm or less, no visceral pleural invasion and not MSB invasion