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21 Cards in this Set

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How do glucocorticosteriods effect the body?
*Produces anti-inflammatory effect
*Metabolism of carbs, fats, and protein
*Exerts immunosuppressive effect
What are corticosteriods?
Hormones that are produced in the body by the adrenal glands
What are the adverse effects of corticosteriods?
*PU/PD
*Thinning of skin, muscle wasting, impaired healing
*polyphagia and weight gain
*gastric ulcers
*prolonged and/or increased fracture remodeling
*immunosuppression - infections
*Iatrogenic hyper and hypoadrenalcortiscism
What clinical considerations should be taken when using corticosteriods?
*they are not curative, only ameliorative
*close observation is needed during therapy
*blood testing during prolonged therapy
*doses should start high, than gradually taper off to maintenance
*doses may require adjustment
*should never be abruptly discontinued
What are the contraindications of corticosteriods?
*patients w/peptic ulcers
*diabetics
*blood dyscrasias
*use cautiously w/ kidney,liver and heart disease
*pregnant or lactating animals
*glaucoma
Corticosteriods are catergorized by what?
hours of duration
What are the corticosteriods?
*Dexamethasone (Azium), Betamethisone
*Prednisolone, prednisone
*Methylprednisolone (Depo-Medrol)
*Prednisolone sodium succinate (Solu-Delta-Cortef)
*Triamcinolone (Vetalog, Panalog)
What are the uses of Dexamethasone?
*Musculoskeletal
*Cerebral swelling
*Hypovalemic shock
What are the routes of administration for Dexamethasone?
*oral
*parenteral
*topical
What is the duration of Dexamethasone?
*Long acting
*greater than 48hrs
Why is Dexamethasone not recommended for cats?
takes longer to metabolize
Why is Prednisone used orally?
less prone to gastric irratation
Why is Prednisolone used more for injections and topical solutions?
its more soluble
What is the duration of prednisolone and prednisone?
intermediate acting
12-36 hours
What is methprednisolone (depo-medrol) commonly used for?
*skin, asthma, allergies
*steriod of choice in cats?
Depo-medrol duration of action is?
*2 weeks
*classified as intermediate-acting steriod
*Methyl base give it a longer action
Which corticosteriod is used for the treatment of shock?
Prednisolone sodium succinate (solu-delta-cortef)
Solu-delta-cortef is administered how?
IV only
What is the duration of Prednisolone sodium succinate (solu-delta-cortef)?
ultra short acting
less than 12 hours
What is traimcinolone (vetalog, panalog) used for?
skin allergies
What is the duration of action of Triamcinolone (Vetalog, panalog)?
Intermediate acting
has strong half life