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28 Cards in this Set
- Front
- Back
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Three things that occur when eating a high glycemic meal
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Increase free fatty acids
Postprandial hyperglycemia Counter regulatory hormone secretion |
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How can we keep from insulin resistance?
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Increase fruit, veggies, legumes intake
Limit intake of potatoes and concentrated sugars |
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What enzyme cleaves a glucose unit from glycogen
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Glycogen phosphorylase
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The presence of what enzyme in the liver and kidney allows these organs to release glucose back into the blood?
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G 6 phosphatase
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Fructose and galactose go directly to..
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The liver
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Once galactose and fructose are in the liver they can then..
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...
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Where is glycogen stored?
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Liver and muscles
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What takes glucose to g6p?
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Atp
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Hexokinase occurs in
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The muscle
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Glucokinase occurs where?
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The liver
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Kinase always require
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Atp
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What's the opposite ofa kinase?
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A phosphatase
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What's the key intermediate?
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Glucose 6 phosphate
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Gluconeogenic precursors
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Galactose
Fructose Lactate Pyruvate Krebs cycle intermediates Gluconeogenic AA Odd chain fatty acid -glycerol backbone of FA |
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What types of fatty acids do we generally eat
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Even chained
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What type of enzymes cleave alpha 1-6 bonds?
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Debranching enzymes
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Enzyme that turns g6p to glucose?
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G 6phosphatase
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Which condition would you expect in someone with a defect in the glucose 6-phosphatase gene?
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Hypoglycemia
Hepatomegaly |
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Most common disease to affect CHO metabolism is known as
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Von Gierke'sdisease aka glycogen storage diseas
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There is reciprocal regulation of glycogen synthase and..
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Glycogen phosphorylase
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Regulatory enzyme of glycolysis
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Phosphofructokinase (pfk 1)
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Dehydrogenase does what?
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Produces NADH
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Substrate level phosphorylation means
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Making ATP
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How does fructose enter glycolysis?
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Via fructokinase
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Fructose is unregulated basically.. This means more acetyl coa which leads to..
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More fatty acid synthesis!
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The most important allosteric regulator of glycolysis/glucose oneness is..
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F 2,6 bisphosphate
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How does NADH get transferred from the cytoplasm to the mitochondrial membrane?
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Glycerol 3phosphate (brain and muscle)
And the Malays aspartate shuttle |
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Von Gierke'sdisease is caused by a deficiency of which enzyme?
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Glucose 6 phosphatase
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