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89 Cards in this Set

  • Front
  • Back

Inflammation and its consequences of Asthma

caused by allergens, results in


bronchoconstriction and is usually reversible

Inflammation and its consequences of COPD

caused by cigarette smoke, results in small airway narrowing and alveolar destruction and is irreversible

What is, Intermittent, reversible, affects only the airways not alveoli and is caused by inflammation, hyper-responsiveness, airway edema and remodeling

Asthma

3 most common symptoms of asthma

cough, dyspnea and wheezing

Definition of Asthma

a chronic inflammatory disorder of the airways in susceptible individuals, this inflammation caused recurrent episodes of wheezing, breathlessness, chest tightness and coughing, particularly at night or early in the morning. These episodes are usually associated with widespread but variable airflow obstruction that is often reversible either spontaneously or with treatment

Types of Asthma

Intrinsic, Extrinsic, Mixed

Characteristics of Intrinsic Asthma

Non-allergenic, non-atopic- non-immunologic, triggers include respiratory infection, exercise, dust, cold air, inhalation of fumes, aspirin deranged autonomic nervous control leads to mucosal wall edema, bronchial smooth muscle constriction.

Characteristics of Extrinsic Asthma

Allergenic, atopic, immunologic, triggers include pollens, animal dander, dust, molds. inhaled allergen couples with antibody on mast cell leads to release of slow-reating substance of anaphylaxis, histamine or other mediators leads to mucosal wall edema and bronchial smooth muscle constriction

Intermittent Asthma

symptoms less than 1 time a week at night less than or equal to 2 a month. asymptomatic and normal between attacks.

Mild Persistent Asthma

day symptoms more than once a week but less than once a day attacks may affect activity and night symptoms greater than 2 times a month

Moderate persistent asthma

daily symptoms, attacks affect activity night symptoms more than once a week

Severe persistent asthma

continuous day symptoms, limited physical activity and frequent night symptoms

Types of Asthma Drug Therapy

Relievers = Short acting B2-agonists


Controllers = long-acting B2-agonists


Preventers = inhaled corticosteroids


combinations



Complications of Asthma

Status Asthmaticus, life threatening can lead to respiratory failure 10% require ventilatory assistance and ICU


Symptoms: mimic attack but more severe and longer. severe anxiety, fear of suffocation, diaphoresis, PEF decreased, neck vein distention, HTN, Tachycardia, Tachpnea Dysrhythmias


Treatment: immediate hospitalization, treatment of hypoxia, fluids, meds and monitoring

COPD - Chronic Obstructive Pulmonary Disease Characteristics

-chronic bronchitis and emphysema


contributing factors= smoking, recurrent infections, air pollution, heredity, aging



Emphysema

"Pink Puffers" loss of the lung's elastic recoil, causing the respiratory bronchioles to collapse upon expiration

Chronic Bronchitis

"Blue Bloater" Inflammation and structuralchanges, increased mucus,

Panlobar Emphysema

Destruction of bronchiole, alveolar duct and alveoli, little inflammation, hyper-expanded chest, work on exhalation

Centrilobar Emphysema

Derangement of the V/Q ratios, chronic hypoxemia, hypercapnea, polucuthemia and right sided heart failure

COPD Clinical Manifestations

Chronic cough, sputum productions and dyspnea on exertion, weight loss common, increased number of respiratory infections, in primary emphysema will have "barrel chest"

Diagnosis of COPD

Thourgh H & P, spirometery to evaluate airflow obstruction. FEV1/FVC will be less than 70%, reversibility will be tested, chest x ray, ABGs, Screenign for alpha1-antitrypsin deficiency classified by five stages

Medical management of COPD

smoking cessation to slow progression, may use chantix, wellbutrin, nortiptyline, or clonidine. Bronchodilators- beta agonists, anticholinergics, methyxanthines, combinations, nebulized medications, inhaled and systemic corticosteroids, influenza and pneumococcal vaccines. Oxygen therapy "severe copd" High fat low CHO diet

Nursing Management of COPD

Education, breathing exercises, inspiratory muscle training, activity pacing, self-care activities, physical conditioning, O2 therapy, Nutritional therapy,coping measures

Chronic Bronchitis

Is a disease of the airways, is defined as the presence of cough and sputum production for at least 3 months in each of 2 consecutive years

Signs and Symptoms of Chronic Bronchitis



Dyspnea, fever, tachypnea, productive cough, clear to purulent sputum, pleuritic chest pain, diffuse rhonchi and crackles heard on auscultation, Respiratory acidosis, increased hemoglobin, digital clubbing, cardiac enlargement, leads to right sided heart failure

Blue Bloater

Chronic Bronchitis



Pink Puffer

Emphysema

Nursing Management of Bronchitis

improving airway clearance, smoking cessation, keep room dust free, administer bronchodilators, use postural drainage position, encourage coughin, encourage fluid intake, improve breathing patter, use pursed-lip breathing at intervals and during periods of dyspnea administer antibiotics, improve gas exchange, check ABG's, O2 therapy, inspiratory muscle training, encourage frequent small meals, avoid gas producing foods, monitor weight, exercise as possible with o2

Nutritional Therapy related to COPD

goal: decrease dyspnea and conserve energy


rest at least 30 mins prior to eating, use bronchodilator before meals, select foods that can be prepared in advance, 5-6 small meals daily to avoid bloating, avoid foods that require a great deal of chewing, avoid exercises and treatments 1 hour before and after eating, avoid gas-forming foods, high calorie and high protein diet, supplements, avoid high carbs to prevent increase in CO2 load

Primary Pulmonary hypertension (PPH)

occurs in the absence of other lung disorders cause is unknown. blood vessel constriction with increasing vascular resistance in the lung. The hear fails (cor pulmonale) without treatment death occurs within 2 years

Management of PPH

warfarin therapy, calcium channel blockers, endothelin-receptor antagonists, natural and synthetic prostacyclin agents, digoxin and diuretics O2therapy

Cor Pulmonale

hypertrophy of R side of heart from pulmonary hypertenstion. eventual R side failure. (JVD, hepatomegaly, RUQ tenderness, ascites, epigastric distress, peripheral edema)

Interstitial Pulmonary Disease

affects the alveoli, blood vessels and surrounding support tissue of the lungs rather than the airways. restrictive disease- thickened lung tissue, reduced gas exchange, slow onset of disease, dyspnea most common symptoms

Cystic Fibrosis

Affects the sinuses, lungs, skin, liver, pancreas, intestines and reproductive organs, thick sticky mucus blocks airways, bacterial infections occur often and blood is in muscous

Management of CF

breathing retraining- pursed lip and diaphragmatic, coughing, aerosol-nebulization for meds. percussion, vibration, postural drainage position so gravity helps drainage, percuss and vibrate to help loosen secretions dont do right after meals

How to assess the Endocrine System
Health history, energy level, hand and foot size changes, headaches, urinary changes, heat/cold intolerance, changes in sexual characteristics, personality changes
Physical assessment, appearance including hair distribution, fat distribution, quality of skin, appearance of eyes, size of hands and feet, peripheral edema, facial puffiness, vital signs

Diagnostic testing of the endocrine system

serum levels of hormones, antibody testing, urinary tests to measure by-products, stimulation tests, suppression tests

Types of Pituitary Tumors

Eosinophilic, Basophilic and Chromophobic

Eosinophilic Tumors

may result in gigantism or in acromegaly. may suffer from severe headaches, visual disturbances, decalcification o the bone, endocrine disturbances

Basophilic tumors

may cause cushing's syndrome w/ features of hyperadrenalism, truncal obesity, amenorrhea, osteporsis

Chromophobic Tumors

90% of pituitary tumors, present with lowered BMR, obesity, somnolence, scant hair, low body temp, headaches, visual changes

Anterior Pituitary produces these hormones

Growth hormone, adrenocorticotropic, thyroid stimulating, follicle stimulating, luteinizing, and prolactin

Hyper-pituitarism

often seen in target organs ie: thyroid, adrenals, growth hormone excess, giantism, early childhood, acromegaly adults 30s and 40s

Hypo-pituitarism

rare usually from tumor or trauma, more relevant in pediatric, obstetric populations, often non-specific but may be seen in target organs,

Syndrome of Inappropriate Antidiuretic Hormone SIADH

Excessive ADH secretion, retain fluids and develop a dilutional hyponatremia, often non-endocrine. caused by disorders of the CNS like head injury, surgery tumors, infections, or medications. Management eliminate cause, give diuretics, fluid restriction, I&O, daily weight, lab chemistries. restoration of electrolytes must be gradual

Manifestations of SIADH

excessive thirst


urinary specific gravity of 1.001-1.005

Diabetes Insipidus

deficiency of ADH, Excessive thirst, large volumes of dilute urine, can occur secondary to brain tumors, head trauma, infections of the CNS, and surgical ablation or radiation. Nephrogenic DI- relates to failure of the renal tubules to respond to ADH can be related to hypokalemia, hypercalcemia and to medications

Symptoms of Diabetes Insipidus

uncontrollable thirst, a yearning for ice water, increased urine volume of diluted reaching 2.5 to 15 liters a day. Nocturia, hypotension, tachycardia, poor skin turgor, dry mucous membranes, irritability, decreased cognition, hyperthermia, ataxia, coma

Assessment of Thyroid

inspect gland, observe for goiter, check TSH, serum T3 and T4. T3 resin uptake, radioactive iodine uptake test and thyroid scan

Thyroid Scan

helps determine the location, size, and shape of gland. "Hot" areas = increased function and "cold" areas = decreased function

Radioactive iodine uptake test

measures rate of iodine uptake. hyperthyroidism will exhibit high rate of uptake while hypothroidism will have low uptatke

Hyperthyroidism

Excess T3, T4 or both, more likely in men, iodine deficiency contributes


Graves disease

Graves Disease

diffuse toxic goiter, autoimmune, hyperplasia from thyroid stimulatin abs activate production of hormones. remissions/exacerbations can progress to destroy thyroid = hypothyroidism

Thyrotoxicosis

nervousness, irritable, apprehensive, palpitations, heat intolerance, skin flushing, tremors, possibly exophthalmos, increased sensitivity to catecholamines, can occur after irradiation or presence of a tumor

Symptoms of Hyperthyroidism

palpitations, heat intolerance, nervousness, insomnia, breathlessness, increased bowel movements, light/absent menstrual periods, fatigue, tachycardia, trembling hands, weight loss, muscle weakness, warm most skin, hair loss, staring gaze

Treatment of Hyperthyroidism

Block effects, stop over secretion with meds, thyroid ablation with RI, subtotal thyroidectomy, nutrition, Eye care, restful environment

Thyroid storm what is it how do you treat it

is an acute release of thyroid hormones in response to administration of RI. Symptoms include; high fever, tachycardia, delirium, chest pain, dyspnea, papitations, weight loss, diarrhea, abdominal pain. Treat with O2 IV fluids with dextrose, hypothermic measures, steroids to treat shock and adrenal deficiency, iodine to decrease output of T4 beta blockers, PTU or Tapazole impedes formation of thyroid hormone and blocks conversion of T4 to T3

Nursing Management of Hyperthyroidism

Reassurance r/t emotional reactions, eye care, maintain body temp, adequate caloric intake, manage complications such as dysrthmias and tachycardia, education

Hypothyroidism

insufficient hormone. often from atrophy of thyroid from Graves/ Hashimoto's disease, inadequate TSH, Surgical removal, goitrogens, iodine def areas. if long-standing can lead to Myxedema(coma)

Myxedema

accumulation of mucopolysaccharides in SC and interstitial tissues is the extreme form of hypothyroidism can progress to shock

Signs/symptoms of hypothyroidism

increased weight, constipation, perioribital edema, hoarse voice, slower movements, paresthesias, intolerance to cold, mentrual changes, decreased sweating response, dry coarse and cold skin, hair loss, apathy, brittle nails and hair

Management of Hypothyroidism

thyroid hormone meds, low cal diet, prevent constipation, vital signs, cardiac monitoring, safety

Management of Myxedema

cautious fluid replacement, glucose to restore glycemic levels, avoid rapid overheating to do increased oxygen demands but keep warm, may give levothyroxine IV, modify activity, high fiber foods

Hyperparathyroidism symptoms

depression, poor concentration, memory deficits, muscle weakness, fatigue, weight loss, anemia, anorexia, ectopic calcifications, shortened q-t interval, polyuria, polydipsia, metabolic acidosis, gout, osteopenia, peptic ulcers, pancreatitis, nausea and vomitting

Management of hyperparathyroidism

surgical removal, hydration therapy, increase mobility, fluids, prune juice and stool softeners for constipation watch for s/s of tetany postsurgially as well as cardiac dysrhythmias and hypotension

Hypercalcemic Crisis

seen with levels greater than 15mg/dl, can result in life threatening neurologic, cardiovascular and renal symptoms, treatments include hydration, loop diuretics, phosphate therapy, calcitonin or mithramycin

Hypoparathyroidisim

seen most often following removal of thyroid gland, parathyroid glands or following radical neck surgery. results in increased bone phospate and decreased blood calcium levels. decreased absorption of calcium

Symptoms of Hypoparathyroidism

tingling or burning in fingertips, toes and lips. muscle aches or cramps of legs, feet, abdomen or face. twitching or spasms of muscles especially around mouth, fatigue/ weakness. dry coarse skin, patchy hair loss, brittle nails, anxiety or nervousness, headaches, depression, mood swings, memory loss

Diagnosis of Hypoparathyroidism

low blood CA+ level, low parathyoid hormone level, high blood phosphorus level, low blood magnesium level, ECG, Urine calcium test, x-rays and bone density tests, trousseau's sign, chvostek's sign

Management of Hypoparathyroidism

calcium supplements, vitamin D, diet high in calcium low in phosphorus, lifetime drug therapy, medical alert bracelet, reduce stress, Tetany biggest danger

Pheochromocytoma

usually a benign tumor, originates from the chromaffin cells of the adrenal medulla, usually develops between 40-50, 10% are malignant, may be associated with thyroid carcinoma or parathyroid hyperplasia or tumor

Manifestations of Pheochromocytoma

headache, diaphoresis, palpitations, hypertension, hyperglycemia, tremors, flushing, anxiety, blurred vision, feeling of impending doom. BP's exceeding 250/150 can occur

Manifestations of Cushing's Syndrome

Cataracts, glaucoma, hypertension, HF, Moon face, turnical obesity, buffalo hump, sodium retention, hypokalemia, hyperglycemia, negative nitrogen balance, altered calcium metabolism, osteoporosis, compression fractures, peptic ulcers, pancreatitis, thinning of skin, striae, acne and mood alterations

Cushing's

caused by increased glucocorticoids especially cortisol, usually related to pituitary adenoma more common in women, Associated with 5h's

What are the 5 H's

hypertension, headache, hyperhidrosis, hypermetabolism, hyperglycemia

Management of Cusings

bedrest, elevated HOB, ICU, Nipride, Calcium channel blockers and beta blockers, surgical management, steroid therapy

Primary Addison's Disease

all 3 steroids decreased, autoimmune, part of polyendocrine deficiency syndrome, possible causes are: TB, hemorrhage, infract, infection, AIDS and CA

Secondary Addison's Disease

No ACTH, sudden stop of steroids

Manifestations of Addison's Disease

muscle weakness, anorexia, dark pigmentation, hypotension, hypoglycemia, low sodium levels, high postassium levels, gi disturbances, changes in distribution of hair,

Addisonian Crisis

circulatory shock, pallor, apprehension, weak and rapid pulse, rapid breathing, low BP, headache, nausea, abdominal pain and diarrhea, can be brought on by overexertion, exposure to cold, acute infection, decrease in salt intake

Types of Hematological Studies

CBC, PT/INR, PTT, TT, Fibrinogen, D-dimer, Fibrin degradation products, Bone marrow aspiration and biopsy

Iron deficiency

most common type of anemia, common causes are blood loss an diet

Hemolytic Anemia- Types

Sickle cell, thalassemia, hereditary spherocytosis, polythemia, leukopenia, lymphopenia, neutropenia, leukemia

Sickle Cell characteristics and management

inherited disease, pain is most common symptom, managed with bone marrow transplant, transfusions, hydroxyurea, arginine, oxygen, pain management,infection, emotional support, education, monitor for complications

Myelodysplastic syndrome MDS

myeloid stem cells cause dysplasia, can progress to leukemia. treated with bone marrow transplant, transfusions, education and chelation

Aplastic anemia

decreased bone marrow stem cells, treated with bone marrow transplant, immunosuppressives, splenectomy, transfusions

Anemia of Renal Failure

deficiency of erthropoietin, treat with recombinant erthropoietin (epogen)

Anemia of Chronic illness

inflammation, infection, malignancy treat underlying disease

Thalassemia

hereditary, defective hemoglobin chain synthesis, causing abnormal hemoglobin formation. alpha is mild beta can be fatal managed with transfusions, BMT and teaching