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22 Cards in this Set
- Front
- Back
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Parkinson's Disease Patho
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Imbalance btw ACh and Dopamine
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Parkinson's Disease: CM
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unintentional tremor- Pill rollers palsy
Brady/A-Kinesia Muscle Rigidity |
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Parkinson's Disease: Cognitive and Psychological Dysfunction
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depression in 1/3 of pt
mood swings delayed rxns sleep disturbances(due to decreased dopamine) dementia and memory loss in later stages |
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Drugs to treat Parkinson's Disease
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Dopaminergics- levodopa, carbidopa-levodopa, amantidine
Comtan |
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Myasthenia Gravis
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disease affecting neuromuscular transmission of voluntary muscles
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Myasthenia Gravis: CM
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extreme muscular weakness
diplopia ptosis sleepy, masklike face difficulty chewing/swallowing |
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Myasthenia Gravis: diag. test
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Injection of Tensilon- + result is improvement within 30sec
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Myasthenia Gravis: Management
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Anticholinergic agents to increase ACh(Mestinan, Mytelase, porstigmin)
Immunosuppressive therapy(corticosteroids, cytoxic drugs) Plasma exchange-temp. decreases antibody numbers |
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Myastenic crisis
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sudden onset of weakness and respiratory distress, inability to swallow
due to undermedication or no meds |
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Cholinergic crisis
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caused by OVERmedication
resp. distress + N/V/D |
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Medications that aggravate MG
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beta blockers, antibiotics, anticonvulsants, psychotropics
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What is the most common form of dementia?
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Alzheimer's Disease
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Best diagnostic evaluation for Alzheimers
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MRI, brain scan
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Dementia w/ Lewy Bodies
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2nd most frequent cause of dementia
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Dementia w/ Lewy Bodies: CM
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forgetfulness
difficulty in thinking disorientation loss of judgment personality changes |
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Medications to treat Dementia w/ Lewy Bodies
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^ACh levels
Cognex, excelon, Reminyl, Aricept, Namenda |
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Carotid Doppler Studies
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evaluates velocity of blood flow through carotid arteries and identifies occlusive disease
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Myelogram
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identifies lesion of spinal cord
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Amyltropic Lateral Sclerosis
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weakness and wasting of muscles under voluntary control. no sensory or cognitive change
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CJD
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brain degeneration without inflammation. Can be transmitted
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Guillian-Barre Syndrome
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inflammatory demyelinating disorder of the peripheral nervous system char. by acute onset of motor paralysis
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Huntington's Disease
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progressive, degenerative, inherited neurologic disease char. by increasing dementia and chorea
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