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21 Cards in this Set

  • Front
  • Back
resins
ADR: GI, hemorrhoids, diverticulitis, malabsorption of vitamins. Do not take if TG> 400

niacin

ADR: flushing, itching, GI, hyperglycemia, hyperuricemia, hepatitis



CI: hepatic insufficiency, gout, uncontrolled DM, peptic ulcers

statins

ADR: hepatitis, myositis, cns disturbances T2DM, thrombocytopenia, GI



CI: hepa insufficiency

fibrates
ADR: gallstones, libido, hepatitis, breast tenderness, inc risk of myositis when taken with statins

PDE5i

ADR: nose bleeds, priapism, hypotension, hearing loss, vision loss



CI: niacin

bosentan/ambrisentan

ADR: hepatox, anemia, edema



CI: bosentan: glyburide, cyclosporine, pregnancy

marcitentan

ADR: hepatox, anemia, UTI, bronchitis, pregnancy

prostanoids

ADR all: hypotension, flu-like sx, jaw pain, edema


epoprostenol: HTN rebound


treprostinil inh: QTc prolongation


iloprost: cough



CI: caution in hepatic impairment

riociguat

ADR: hypotension, bleeding, pulmonary veno-occlusion



CI: pregnancy, nitrates

ranolazine

ADR: QT prolongation, bradycardia, constipation



CI: QT problems, hepatic impairment, moderately potent 3A4i

BB

ADR: bradycardia, fatigue, diziness, CHF exacerbation, bronchospasms



CI: asthma

CCB

ADR: reflex tachycardia, constipation, gingival hyperplasia, periph edema, bradycardia, AV block, CHF exacerbation

alpha-1 blockers

ADR: orthostatic HTN, 1st dose phenomenon

central alpha-2 agonists

ADR: rebound HTN


clonidine: anticholinergic


methyldopa: hemolytic anemia, hepatitis

direct arterial vasodilators

hydralazine: lupus-like


minoxidil: hypertrichosis

peripheral adrenergic antagonist

ADR: sedation, parasympathetic effects, bradycardia

ACEi/ARB

ADR: rockan



CI: renal artery stenosis, pregnancy

thiazides

ADR: hyperglycemia, uricemia, lipidemia, GI, photosensitivity, electrolytes, sexual dysfunction, ortho hypotension

loop

same as thiazide + ototoxicity IV

Na channel blockers

ADR: GI, photosensitivity, increased K, hyperuricemia

aldosterone-R antagonist

Na channel + gynecomastia