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84 Cards in this Set
- Front
- Back
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Norepinephrine
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What is it?
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Dopamine
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What is it?
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Epinephrine
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What is it?
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Isoproterenol
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What is it?
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Amphetamine
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What is it?
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Phenylephrine
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What is it?
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Ephedrine
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What is it?
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Methoxamine
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What is it?
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Beta 2 agonists
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-terol, -but
Albuterol Salmeterol Terbutaline Metaproterenol Ritodrine |
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Alpha 2 agonists
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DineGuanDopa
Clonidine Guanfacine Guanabenz alpha methyldopa |
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Beta 1 agonists
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DoXaPren
Dobutamine Xameterol Prenalterol |
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Alpha 1 agonists
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PMMM, PhenMidMetaMetho
Phenylephrine Midodrine Metaraminol Methoxamine |
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Substitution on N give compound what property?
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Increased Beta effect
Isoproterenol |
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Removal of hydroxyl from benzene ring give compound what property
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Less polar, can cross BBB
Amphetamine, Ephedrine |
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Tx for cardiogenic shock
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Dobutamine B1
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Tx for cardiac arrest
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Epinephrine
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Tx for anaphylaxis
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Epi
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Tx for asthma
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Beta 2 sel.
Albuterol Salambutol Terbutaline Salmeterol |
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Nasal/ocular decongestant
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Oxymetazoline
Xylometazoline Terahydrozoline |
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Teaching about Nasal/Ocular decongestant use
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If they dont work after the first use try something else, repeated use may cause hypotension due to clonidine like stimulation
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Delay of premature labor
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Terbutaline
Salbutamol Ritodrine |
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Blocks VMAT
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Reserpine
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Inhibits Dopamine synthesis
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Carbidopa
Blocks Dopa decarboxylase |
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Inhibits uptake 1
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Cocaine
Imipramine - TCA Desipramine - TCA |
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Blocks COMT
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Tolcapone
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MAOIs
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Selegiline
Pargyline |
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Promotes NE release, dietary restriction w/ MAOI
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Tyramine
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CNS stimulants
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Amphetamine - Narcolepsy
Methylphenidate - ADHD |
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Dopamine agonists
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Bromocriptine
Fenoldopam Dopamine |
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NS Beta agonist
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Isoproterenol
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Beta 3 agonists
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research drugs
#' & letters |
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NS adrenergic agonist
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Epinephrine
Norepinephrine |
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Appetite suppressant
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Ephedrine
Amphetamine |
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CNS stimulant, inreased mood & alertness
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Amphetamine
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Can act as an inotrope or pressor depending on dose
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Dopamine
Renal efect @ low dose Beta effect @ med. dose alpha efect at high dose |
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NS adrenergic blockers
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Labetalol
Carvedilol |
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NS alpha blockers
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Phentolamine - reversible
Phenoxybenzamine - irrev. |
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Used in treatment of pheochromocytoma
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Phenoxybenzamine
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Alpha 1 blockers
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-azosins
Prazosin Doxazosin Terazosin Indoramine |
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Alpha 2 blockers
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Yohimbine
Rauwolscine Tolazoline |
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NS beta blockers
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PROs CARry SOme PENs to PINch TIMs NADs
Propranolol Carteolol Sotalol Penbutolol Pindalol Timolol Nadolol |
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Beta 1 blockers
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MEn ATE CELery ESpecially BETween ACts
Metoprolol Atenolol Celiprolol Esmolol Betaxolol Acebutolol |
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Beta 2 blockers
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Butoxamine
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Beta 3 blockers
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#'3 & letters
Rsearch drugs |
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Which alpa 1 agonist is a produg?
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Midorine
PO Neo (Neosynephrine) |
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Midodrine
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PO alpha 1 agonist
Tx postural hypotension May cause hypertension when supine |
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Clonidine
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alpha 2 agonist
Tx HTN & Glaucoma (apraclonidine) ETOH/Opiate withdrawl Suppress diarrhea in diabetics |
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Guanabenz
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Alpha 2 agonist
Tx HTN |
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Guanfacine
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Alpha 2 agonist
Tx HTN |
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Alpha methyldopa
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alpha 2 agonist
Tx HTN |
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Dobutamine
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Beta 1 agoinst
Tx cardiogenic shock Racemic mixture: +isomer is a beta 1 agonist & alpha 1 blocker, -isomer is an alpha 1 agonist. result is B1 effect only |
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xameterol
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beta 1 agonist
increases CO, has less bronchodilation & tachycardia effect |
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Metaproterenol
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Beta 2 > beta 1 agonist
Tx bronchospasm/asthma |
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Terbutaline
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Beta 2 agonist
Tx asthma, premature labor |
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Albuterol
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Beta 2 agonist
Tx bronchospasm/asthma |
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Ritodrine
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Beta 2 agonist
iv to Relax uterus & delay labor |
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Salmeterol
Formaterol |
Beta 2 agonist
long (12 hr.) duration due to lipid solubility Tx asthma |
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Albuterol
Pirbuterol Bitolterol Metaproterenol Terbutaline |
beta 2 agonists
Tx asthma |
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Phenmetrazine
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Sympathomimetic
similar to amphetamine Appetite supressant |
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Pemoline
Methyphenidate |
Amphetamine variants
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Phenylpropanolamine
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Sympathomimetic
in OTC wight loss products Weak mood effect |
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Psuedoephedrine
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Sympathomimetic
in OTC decongestants treat stress incontinence in women |
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Ephedrine
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Sympathomimetic
Long duration of action Releases stored NE/EPI Mimics Epi in effect Nasal decongestant and pressor |
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Cocaine
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Sympathomimetic
blocks uptake 1, increasing duration of NE in synapse |
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Tyramine
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Symopathomimetic
Releases stored catecholamines Effect is increased in presence of MAOI |
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Dietary restriction w/ MAOI
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Avoid tyramine containing foods
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Mixed acting Sympathomimetics
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PEP
Phenylpropanolamine Ephedrine Pseudoephedrine |
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Inhibits vesicular fusion & release of NE
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Guanethedine
Bretylium |
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Used to treat frostbite & diagnose pheochromocytoma
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Phentolamine
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Timolol
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NS beta blocker
No local anesthetic effect Glaucoma tx via dec. AH production |
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Used to treat complete heart block
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Isoproterenol
Epinephrine |
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Used to treat CHF
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Dobutamine
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Class of drugs used to treat asthma
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Beta 2 agonists
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Alpha 1 agonist
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used as a mydriatic agent for retinal examination
Used as a decongestant |
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Blocks rate-limiting step of catecholamine synthesis
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Metyrosine
Blocks tyrosine hydroxylase |
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Carbidopa
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Inhibits dopa decarboxylase & dopamine synthesis
May cause depression |
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Alpha 2 blockers used in glaucoma
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Apraclonidine
Brimonidine |
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D1 agonist used to increase renal blood flow
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Fenoldopam
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Agents used to treat cardiogenic shock
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Dopamine
Dobutamine |
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Epinephrine use in glaucoma
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increases outflow of AH
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MOA of apriclonidine & brimonidine
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Decrease AH secretion
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MOA of Timolol,Betaxolol, Carteolol
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Decrease AH secretion
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Long acting Beta blocker
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Nadolol
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Pemoline
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Used to treat ADHD
Withdrawn due to Hepatic Failure |
