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65 Cards in this Set
- Front
- Back
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Dopamine Uses
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Acute Decompensated HF
Cardiogenic Shock |
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Dobutamine Uses
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Acute Decompensated HF
Cardiogenic Shock |
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Milrinone Uses
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Acute Decompensated HF
Cardiogenic Shock |
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Dopamine Receptor Effect
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Beta 1 Receptor Agonist
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Dopamine PK
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IV
Short half life |
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Dopamine Receptors and Effects
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DA inc renal bloodflow and urine output
Beta 1 Inc Inotropy Inc CO Alpha 1 Inc PVR |
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Dopamine A/E
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Arrhythmias
Inc O2 Consumption |
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Dobutamine PK
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IV
Short half life |
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Dobutamine Receptors and Effects
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Beta 1 Inc Ino, Inc CO
Beta 2 vasodilation dec PVR |
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Dobutamine A/E
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Arrhythmia
Inc O2 Comsumption |
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Milrinone MOA
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Inhibit PDEIII in heart and vessels
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Milrinone Effects
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Inc inotropy
Inc CO Dec PVR |
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Milrinone A/E
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Arrhythmias
Thrombocytopenia No tolerance |
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Albuterol Receptor and Effect
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Beta 2 agonist
Bronchodilation Vasodilation Smooth muscle relaxation |
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Albuterol Uses
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Bronchial asthma
Chronic bronchitis Emphysema Premature labor |
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Norepinephrine Receptor and Effect
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Alpha 1 Agonist
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Norepinephrine Uses
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Hemorrhage control
With local anesthetics Shock Sepsis Surgery Orthostatic hypotension Opthalmic dilation |
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Pseudoephedrine Receptor and Effect
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Alpha 1 Agonist
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Pseudoephedrine Uses
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Cough
Cold Congestion |
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Pseudoephedrine A/E
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Inc BP
Insomnia Convulsions |
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Amitriptyline Drug Type
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CNS Indirect Sympathomimetic
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Amitriptyline Uses
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Tricyclic antidepression drug
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Cocaine Drug Type
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CNS Indirect Sympathomimetic
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Amphetamine Drug Type
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CNS Indirect Sympathomimetic
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Adderall Drug Type
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CNS Indirect Sympathomimetic
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Methylphenidate Drug Type
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CNS Indirect Sympathomimetic
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Focalin Drug Type
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CNS Indirect Sympathomimetic
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Cocaine Uses
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Local anesthetic
Vasoconstrictor |
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Cocaine MOA
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Block Na channels
Block DAT Block SERT Block NE reuptake via amine pump |
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Cocaine A/E
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HTN
Cardiotoxic Ventricular Arrhythmias MI Myocardial Ischemia |
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Amphetamine MOA
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Blocks NET (DAT & SERT)
Promotes NT release |
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Amphetamine Uses
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Decrease appetite
Narcolepsy ADHD |
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Amphetamine A/E
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Ventricular Arrhythmias
Inc BP Myocardial ischemia MI CNS Manifestations |
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Metoprolol XL Drug Type, Use
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Beta blocker
Succinate Salt Heart Failure |
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Metoprolol XL Metabolism
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CYP2D6
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Metoprolol Drug Type, Use
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Beta blocker
Tartrate Salt HTN |
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Pindolol Drug Type & Activity
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Beta blocker
Intrinsic Sympathomimetic Activity Partial Agonist |
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Carvedilol Drug Type & Activity
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Beta Blocker
Alpha blocking activity Ca Reentry block Antioxidant activity Inc NO production |
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Carvedilol Use
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HF
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Carvedilol Metabolism
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CYP2D6
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Terazosin Drug Type and Uses
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Alpha 1 Blocker
HTN BPH |
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Terazosin Effects
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Dec PVR
Dec Venous Return Relax bladder neck Relax prostate smooth muscle |
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Terazosin A/E
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IFIS
Fluid Retention Postural Hypotension 1st dose Syncope |
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Tamsulosin Drug Type and Use
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Alpha 1 Blocker
BPH |
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Tamsulosin A/E
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Postural hypotension
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Phentolamine Drug Type and Use
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Non-competitive Alpha 1 & 2 blocker
Pheochromocytoma |
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Phenoxygenzamine Drug Type and Use
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Irreversible Alpha 1 & 2 blocker
Pheochromocytoma |
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Selegiline Drug Type
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MAO Inhibitor
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Selegiline Effects
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Stops catecholamine & Seratonin Breakdown
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Selegiline Uses
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Depression
Parkinson's Disease |
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Selegiline A/E
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Orthostatic hypotension
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Clonidine Drug Type
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Alpha 2 Agonist/Sympatholytic
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Clonidine Effects
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Activate Alpha 2 receptors in NTS
Decrease sympathetics Decrease PVR |
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Clonidine Uses
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HTN
Opiate withdrawal Nicotine withdrawal Vascular headaches Chronic pain Glaucoma Tourette's syndrome |
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Clonidine A/E
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Drowsiness
Drymouth Xerostomia |
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Lisinopril Drug Type
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ACE Inhibitor
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Lisinopril Uses
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Heart Failure
HTN Post MI |
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Lisinopril A/E
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Cough (Bradykinin)
Inc K+ Angioedema Loss of taste Hypotension |
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Valsartan Drug Type
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AT1 Receptor Antagonist
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Valsartan Uses
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Heart Failure
HTN Post MI |
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Valsartan Receptor Interaction
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Does not readily disassociate
Not covalent |
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Valsartan A/E
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Hypotension
Inc K+ |
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Aliskiren Drug Type
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Direct Renin Inhibitor
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Aliskiren Effects
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Decrease Angiotension II
Decrease BP |
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Aliskiren Use
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HTN
Used with diuretics |
