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41 Cards in this Set
- Front
- Back
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Epinephrine
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Alpha and Beta agonist
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Norepinephrine
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Alpha and Beta1 agonist
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Isoproterenol
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Beta agonist
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Dopamine
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High doses- Alpha and Beta agonist
Low doses- vasodilation in kidney |
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Tyramine
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Alpha agonist in pts on MAOI, uptake into neuron via pump
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Amphetamine
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Alpha agonist, treat hyperkinetic kids and narcolepsy
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Methamphetamine
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Alpha agonist
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Methylphenidate
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Alpha agonist, treat ADHD
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Ephedrine
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Mixed effect (release NE from storage), Alpha and Beta agonist, treat bronchial asthma, pressor agent, mydriasis without cycloplegia
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Phenylephrine
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Direct effect, Alpha agonist
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Methoxamine
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Direct effect, Alpha agonist, treat tachycardia (reflex bradycardia)
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Metaproterenol
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Beta2 agonist, treat bronchial asthma
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Terbutaline
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Beta2 agonist, treat bronchial asthma, prevent premature labor
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Albuterol
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Beta2 agonist, treat bronchial asthma
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Salmeterol
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Beta2 agonist, treat bronchial asthma
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Ritodrine
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Beta2 agonist, prevent premature labor
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Dobutamine
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Beta1 agonist, treat cardiac insufficiency (increase force of contraction)
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Clonidine
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Alpha2 agonist, decrease sympathetic tone to blood vessels and heart, enhance vagal outflow to heart, treat opioid and ethanol withdrawal
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Alpha-methyl DOPA
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Alpha2 agonist, in CNS converted to alpha-methylnorepinephrine, reduces sympathetic tone
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Alpha-methyl-para-tyrosine
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Inhibits tyrosine hydroxylase to depress catecholamine levels in pts with pheochromocytoma prior to surgery
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Reserpine
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Depletes catecholamines in CNS
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Guanethidine
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Uptake into neuron is via pump, no CNS effects
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6-OH Dopamine
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Destroys adrenergic nerve terminals
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Phentolamine
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Alpha1 blocker, short acting, screen for pheochromocytoma
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Phenoxybenzamine
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Alpha1 blocker, long duration
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Prazosin
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Alpha1 blocker, no reflex tachycardia
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Doxazosin
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Alpha blocker, treat benign prostatic hypertrophy
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Terazosin
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Alpha blocker, treat benign prostatic hypertrophy
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Yohimbine
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Alpha2 blocker
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Propanolol
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Beta blocker, prevent migrane headaches, local anesthetic, hepatic elimination
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Metoprolol
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Beta1 blocker, reduces renin, hepatic metabolism, CNS side effects (fatigue, dizziness, headache, insomnia)
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Atenolol
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Beta1 blocker, long half life, less CNS side effects, renal excretion
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Pindolol
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Beta blocker, renal and hepatic excretion, intrinsic sympathomimetic activity
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Timolol
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Beta blocker, treat glaucoma, prevent reinfarction of myocardium
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Nadolol
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Beta blocker, renal excretion, long duration of action
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Betaxolol
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Beta1 blocker, hepatic metabolism, long half life
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Esmolol
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Beta1 blocker, short half life, emergency control of ventricular heart rate in pts with atria lfibrillation
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Labetalol
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Beta blocker and Alpha1 blocker, decreases plasma renin, antihypertensive without reflex tachycardia, hepatic metabolism
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Carvedilol
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Beta blocker and Alpha1 blocker, antihypertensive, free radical scavenger, treat congestive heart failure
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Cocaine
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Block NE reuptake, local anesthetic
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Tricyclic Antidepressants
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Block catecholamine reuptake into adrenergic nerve terminals, treat depression
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