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34 Cards in this Set
- Front
- Back
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epinephrine
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beta > alpha
direct sympath |
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norepi
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alpha1 > alpha2 > beta1
direct sympath |
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dopamine
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D1 = D2 > beta > alpha
direct sympath (D1 = renal profusion) |
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dobutamine
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beta1 > beta2, alpha
direct sympath |
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ephedrine
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stimulates epi & norepi release
indirect sympath |
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cocaine
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blocks reuptake of norepi, serotonin, dopamine
indirect sympath |
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phenylephrine
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alpha1 agonist
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midodrine
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alpha1 agonist
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clonidine
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alpha2 agonist
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isoproterenol
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beta1 & beta2 agonist
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albuterol, pirbuterol, bitolterol
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beta2 agonist
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terbutaline, ritodrine
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beta2 agonist
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methyldopa
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alpha2 agonist
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phenoxybenzamine, phentolamine
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irreversible alpha antagonist
phentolamine is reversible & short acting |
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prazosin, terazosin, doxazosin, tamsulosin, alfuzosin
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selective alpha1 antagonist
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propranolol, nadolol, pinolol, timolol
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beta1 & beta2 antagonist
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carvedilol, labetalol
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alpha 1, beta1 & beta2 antagonist
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metoprolol, atenolol, esmolol, acebutolol, bisoprolol, betaxolol
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selective beta1 antagonist
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hexamethonium, mecamylamine, trimethaphan
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anti-nicotinics
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pilocarpine
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M1, M2, M3 agonist
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carbachol
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muscarinic & nicotinic agonist
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methacholine
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M1, M2, M3 agonist
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bethanechol
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M2, M3
does not cross BBB |
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atropine, homatropine, tropicamide
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M1, M2, M3 antagonist
atropine analogues (to dilate eyes) |
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scopolamine
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M1, M2, M3 antagonist
crosses BBB |
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benztropine, biperiden, trihexyphenidyl
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M1, M2, M3 antagonist
crosses BBB |
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ipratroprium, tiotropium
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muscarinic antagonist (inhaled)
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oxybutynin
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M1, M2, M3 antagonist
other drugs for urinary incontinence: tolterodine, darifenacin, solifenacin, trospium |
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propantheline
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M3 muscarinic antagonist
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neostigmine, physostigmine
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reversibly inhibits AChE -> nicotinic & muscarinic stim
neostigmine does not cross BBB, physostigmine does |
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edrophonium, pyridostigmine
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reversible inhibit AChE -> nicotinic & muscarinic stim
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tacrine, donepezil, galantamine, rivastigmine
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reversible inhibit AChE
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exhothiophate, isoflurophate
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inhibit AChE -> nicotinic & muscarinic stim
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pralidoxime
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reverse cholinesterase inhibitor binding to AChE
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