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39 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
blood vessels- vasoconstriction
alpha 1 receptor sites
increase peripheral resistance, BP
alpha 1
Pupil dilation
alpha 1
increase closure of urinary bladder sphincter
alpha 1
modulator of norepinephrine release
alpha 2
located on beta cells in pancreas, controls insulin release
alpha 2
stimulate myocardial activity
beta 1
increase heart rate
beta 1
increase lypolysis
beta 1
located on smooth muscle in blood vessels, cause vasodilation
beta 2
dilatin of bronchi
beta 2
increased muscle and liver breakdown of glycogen
beta 2
increased release of glucagon from pancreas
beta 2
relax uterine smooth muscle (during labor)
beta 2
pupil constriction
muscarinic
Increased GI motility
muscarinic
increased secretions (saliva)
muscarinic
increase urinary bladder contraction
muscarinic
slowing of heart rate
muscarinic
causes muscle contraction
nicotinic
autonomic responses
nicotinic receptor sites
affects release of norepinephrine and epinephrine from adrenal medulla
nicotinic receptor sites
affects the heart
beta 1
affects the lungs
beta 2
location and function of beta 2 receptors
in smooth muscle of blood vessels- causes vasodilation
bronchi- causes dilation
periphery- breakdown of glycogen and release of glucagon
uterine muscle- relaxation of muscle
location of alpha 1 receptors
blood vessels- vasoconstriction
iris- dilation
urinary bladder-closure of sphincter
location and function of alpha 2 receptors
nerve membranes- act as modulators of norepinephrine release
beta cells of pancreas- help to moderate insulin release
nerves, pancreas
location and action of beta 1 receptors
in cardiac tissue- increases activity and heart rate
in peripheral tissues- increases lipolysis
Sympathetic Neurotransmitter terminator
Monoamine oxidase (MAO), catechol- O-methyltransferase (COMT)
Parasympathetic Neurotransmitter terminator
Acetylcholinesterase
sympathomimetic drugs (andrenergic agonists) usage
for the treatment of hypotensive states or shock, bronchospasm, and some types of asthma
Adverse Effects of
sympathomimetic drugs
arrhythmias,
hypertension,
palpitations,
angina,
dyspnea
nausea and vomiting, headache, sweating, and piloerection
Phenylephrine ( specific alpha adrenergic agonist)
Topically it is used to treat allergic rhinitis and to relieve the symptoms of otitis media. Ophthalmically it is used to dilate the pupils for eye examination, before surgery, or to relieve elevated eye pressure associated with glaucoma
allergic rhinitis, glaucoma, dilate pupils
Beta-Specific Adrenergic Agonists use
treat bronchial spasm, asthma, and other obstructive pulmonary conditions
Clonidine (specific alpha 2 agonist) action
stimulates directly alpha2-receptors and is used to treat hypertension because its action blocks release of norepinephrine from nerve axons
Phenylephrine - (alpha 1 specific adrenergic) action
binds to alpha 1 receptors- used in many cold and allergy remedies because it is a powerful local vasoconstrictor
adrenergic alpha 1 antagonist (blockers) use
primarily used to treat cardiac-related conditions, BPH, hypertension
Isuprel (beta specific adrenergic agonist) use
shock, cradial standstill,
heart block in transplanted hearts---because increase heart rate,contarctility, conductivity and blood flow
prevention of bronchospasm during anesthesia
symphatolytic drugs(andrenergic antagonists)
inhibits the postganglionic functioning of the sympathetic nervous system (SNS), used as antihypertensives