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81 Cards in this Set
- Front
- Back
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T/F. Epineprine (Adrenalin)stimulates Alpha1, Beta1, and Beta2 receptors
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True
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T/F. Epinephrine is a potent inotropic drug
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True
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What is inotropic?
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Cause vasocontriction of blood vessels
Increases BP and HR Bronchial tube dilation |
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Uses for epinephrine
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Bronchospasms
Allergic reactions (Beta2 stimulation) |
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How is epinephrine administered?
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IM
IV SC Inhalation |
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T/F. Dopamine is inotropic
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True
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Which receptors does dopamine stimulate?
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Alpha1
Beta1 Dopaminergic |
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What is one use of dopamine?
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Acute hypotensive states
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T/F. Dopamine increases vasoconstriction and cardiac output
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True
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T/F. Dopamine constricts renal arteries
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False. Dopamine dilates renal arteries
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T/F. Dopamine is used to improve renal perfusion
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True
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How is dopamine administered?
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IV use only
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T/F. Dopamine can be administered via oral route
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False. Dopamine can only be administered via IV
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T/F. Dobutamine is a catecholamine
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True
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Which is the best statement
A) Dobutamine stimulates Beta1 receptors B) Dobutamine stimulates Alpha1 and Beta1 receptors C) Dobutamine stimulates Alpha1 receptors D) Dobutamine is non selective |
A) Dobutamine stimulates Beta1 receptors
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T/F. Dobutamine decreases the force of cardiac contraction
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False. Dobutamine increases the force of cardiac contraction
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T/F. Dobutamine is used for cardiogenic shock
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True
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T/F. Dobutamine is used for hypovolemic shock
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False. Dobutamine in used for cardiogenic shock only
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T/F. Dobutamine can be administered via IM
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False. IV use only
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T/F. Dobutamine slightly affects peripheral vascular resistance
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True
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Which of the following statements is correct about Albuterol
A) Trade name is Proventil B) Selectively stimulates Beta2 receptors C) Bronchodilator D) Alleviates bronchospasms in COPD E) All of the above |
E) All of the above
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T/F. Albuterol is non selective agonist
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False. Albuterol selectively stimulates Beta2 receptors
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T/F. Albuterol selectively stimulates Alpha1 receptors
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False. Albuterol selectively stimulates Beta2 receptors
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T/F. Albuterol selectively stimulates Beta1 receptors
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False. Albuterol selectively stimulates Beta2 receptors
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How is Albuterol adminstered?
A) Orally B) IV C) Inhalation D) A and C |
D) A and C
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T/F. Albuterol is a non-catecholamine
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True
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T/F. Phenylephrine HCl is also known as Neo-synephine
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True
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Phenylephrine HCl
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Neo-synephrine
Stim Alpha1 receptors Found in OTC cold and allergy prescriptions Produces nasal constriction Relieves nasal stuffiness caused by colds, allergies Parenteral use for acute hypotension |
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Albterol
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Sympathetic amine
Non-catecholamine Selectively stimulates Beta2 receptors Bronchodilator Alleviates in COPD PO, inhalation aerosol |
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Dobutamine
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Dobutrex, catecholamine
Stimulates Beta1 receptor Increases force of cardiac contraction Slightly affects peripheral vascular resistance Used in cardiogenic shock Not used for hypovolemic shock IV use only Careful monitoring needed |
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Dopamine
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Intropin, catecholamine
Stimulates Alpha1, Beta1, and Dopaminergic receptors Used for acute hypotensive state Increases vasoconstriction and cardiac output Dilates renal arteries Used to improve renal perfusion IV use only Careful monitoring needed |
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Adrenalin
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Epinephrin, catecholamine
Stimulates Alpha1, Beta1, Beta2 receptors Potent inotropic agent Causes increase BP and HR Bronchial tubes dilate Used for bronchospasms Used for allergic reactions Adverse effect: Increase HR and BP IM, IV, SC, inhalation |
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Stimulation of Dopaminergic receptors results in:
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Dilation of coronary arteries
Dilation of renal arteries Dilation of visceral blood vessels |
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Stimulation of Beta2 receptors results in:
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Epinephrin release
Bronchodilation GI relaxation Uterine relaxation |
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Stimulation of Beta1 receptors results in:
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N,E,Dopamine release
Increase force of cardiac contraction Increase heart rate Increase release of renin from kidneys Increase angiotensis in blood Increase BP Increase intra ocular pressure |
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Stimulation of Alph2 receptors results in:
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Releaese of norepinephrine
Epinephrine inhibition Decrease BP |
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Stimulation of Alpha1 receptors results in:
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N,E,Dopamine release
Inc cardiac contraction Vasoconstriction of arterioles Vasoconstriction of venules Inc BP Inc HR Pupillary dilation Bladder neck contraction Dec salivation |
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Pseudophedrine
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Sudafed, non catecholamine
Stim Alpha1 receptors Slight stim of Beta1 receptors Vasoconstriction of nasal mucosa Relieves nasal stiffiness Relieves colds and allergies OTC PO |
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Terbutaline
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Brethine, non catecholamine
Stim Beta2 receptors Used as bronchodilator Relieves bronchospasms caused by COPD Used to slow down or stop preterm labor contractions PO, SC |
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What is the trade name of:
Terbutaline |
Brethine
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What is the trade name of:
Pseudophedrine |
Sudafed
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What is the trade name of:
Phenylephrine |
Neo-synephrine
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What is the trade name of:
Albuterol |
Proventil, Ventolin
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What is the trade name of:
Dobutamine |
Dobutrex
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What is the trade name of:
Dopamine |
Intropin
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What is the trade name of:
Adrenalin |
Epinephrine
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What is the trade name of:
Intropin |
Dopamine
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What is the trade name of:
Dobutamine |
Dobutrex
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What is the trade name of:
Albuterol |
Ventolin, Proventil
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What is the trade name of:
Phenylephrine |
Neo-synephrine
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What is the trade name of:
Pseudephrine |
Sudafed
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What is the trade name of:
Terbutaline |
Brethine
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List some alpha adrenergic blocking drugs
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Isoxsuprine (Vasodilan)
Tolazoline (Priscoline) Doxazosin (Cardura) Tamsulosin (Flomax) Prazosin (Minipress) Terazosin (Hytrin) Phentolamine (Regitine) |
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List some beta adrenergic blocking drugs
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Propranolol HCl (Inderal)
Nadolol (Corgard) Metoprolol (Lopressor) Atenolol (Tenormin) Timolol (Timoptic) |
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List some cholinergic drugs
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Urecholine (Bethanechol)
Pilocarpine (Pilocar) Metoclopramide HCl (Reglan) Neostigmine (Prostigmin) Pyridostigmine Bromide (Mestinon) Donepezil (Aircept) |
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List some anticholinergic drugs
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Atropine
Ipratropium Bromide (Atrovent) Dicyclomine HCl (Bentyl) Hyoscyamine Sulfate (Levsin) Tolterodine Tartate (Detrol) Cyclopentolate HCl (Cyclogyl) Benzotropine Mesylate (Cogentin) Trihexyphenidyl HCl (Artane) Propantheline (Pro Banthine) Glycopyrolate (Robinul) Oxybtynin (Ditropan) |
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List 4 classes of drugs that affect the ANS
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Adrenergic agonist
Adrenergic antagonist Cholinergic Cholinergic antagonist |
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What does the ANS regulate?
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Blood pressure
Heart rate Repiration rate Glandular secretions Body temperatures Water balance Urinary secretion Digestive functions |
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What are the three nerve centers of the ANS?
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Medulla
Brain stem Spinal cord |
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What are the branches of the ANS?
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Parasympathetic
Sympathetic |
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Sympathetic nervous system
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Activated under conditions of stress and produces a set of actions called fight or flight
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Parasympathetic nervous system
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Activated under non stressful conditions and produces actions called rest and digest
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Drugs affecting the sympathetic nervous system
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Adrenergics
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Drugs that stimulate the parasympathetic nervous system
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Cholinergics
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Substances the inhibit or excite target cells in the nervous system
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Neurotransmitters
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Agents that stimulate cellular action
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Agonists
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Agents that inhibit cellular function
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Antagonists
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Overdose of a cholinergic drug
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Cholinergic Crisis
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A rapid heart sinus rhythm caused by a variety of ANS effects such as blood pressure changes, fever, or emotional stress
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Reflective tachycardia
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A group of sympathomimetic compounds produced naturally by the body that function as key neurologic chemicals
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Catecholamines
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List the major catecholamines
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Norepinephrine
Epinephrine Dopamine |
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T/F. Compared to other body systems, the ANS itself has remarkably little disease
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True
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Primary neurotransmitters are norepinephrine, epinephrine, and dopamine
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Sympathetic nervous system
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Which system regulates expenditure of energy during stressful situations, illness, danger?
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Sympathetic nervous system
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Which system speeds up physiological responses?
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Sympathetic nervous system
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Which system is also known as the rest and digest?
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Parasympathetic nervous system
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Which systems slows heart rate, food digestion, elimination of waste?
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Parasympathetic nervous system
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Which system slows down many physiologic responses?
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Parasympathetic nervous system
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Inc gastric motility
Dec HR and contractility Bronchial constriction Relaxation of GI Pupillary constriction |
Parasympathetic nervous system
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Sympathomimetics Nursing Implications
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Watch for tachycardia, HTN
Caution with CAD pt monitor EKG Avoid resp irritants Avoid OTC Overuse of vasoconstricting nasal sprays can result in rebound vasodilation |
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IV Dopamine and Phenylephrine
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Central line
Infusion pump Monitor BP and pulse Extravasation precautions Regitine or NS used to vasodilate the affected blood vessel NTG used to vasodilate affected area |
