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15 Cards in this Set
- Front
- Back
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Dopamine |
1. D1 agonist @ low dose = Relaxation of vascular smooth muscle in renal blood vessels = increase flow
IV drip; protects kidneys during hypotensive shock 2. B1 agonist @ medium dose = stimulate heart 3. A1 agonist @ high dose = increase blood pressure |
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Tyramine |
Indirect adrenergic agent Promotes release of NE, usually neuronal |
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Clorgyline |
MAO-A inhibitor Increases serotonin levels Antidepressant |
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Selegiline |
MAO-B inhibitor Increase dopamine levels Treat Parkinson's disease |
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Entacapone & Tolcapone |
COMT inhibitors Increase NE levels Adjunct therapy for Parkinson's disease |
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Ephedrine |
Mixed action; increases release of NE,Epi and non-specific adrenergic agonist
Asthma, nasal decongestant, elevate BP. Oral Adm = penetrates CNS = psychostimulant |
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Isoproterenol |
B1,2 agonist Asthma, tachycardia side effect |
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Metaproterenol & terbutaline |
B2 agonist Asthma, replaced by better drugs |
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Dobutamine |
B1 agonist Stimulate heart in case of cardiogenic shock Rapid & shortlived action |
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Clonidine |
A2 agonist Decreases NE release in CNS Treat hypertension Slowly withdraw drug; may cause rebound hypertension |
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Phenylephrine |
A1 agonist Vasoconstrictor Nasal decongestant, increase BP, induce vagally-mediated slowing of the heart, mydriasis |
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Epinephrine |
Adrenergic agonist, rapid onset short duration Anaphylactic shock, cardiac stimulant, glaucoma, vasoconstrictor helps with anesthetic preps via limiting its diffusion
Toxicities: arrhythmias, hypertension, anxiety, palpitations, headache |
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Albuterol |
B2 agonist Asthma; rescue inhaler |
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Formoterol |
Very selective B2 agonist Long lasting 10-12 hr Prophylactic treatment for asthma. Only be used as add-on following corticosteroid treatment |
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Salmeterol |
Most selective B2 agonist Partial agonist, Long lasting 10-12, but slow onset
Prophylactic treatment for asthma, NOT used as rescue therapy
Used only as add-on following corticosteroid treatment |
