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15 Cards in this Set

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  • Back
Cushing's Syndrome is caused by ______ while Addison's disease is caused by _____.
Excessive levels of glucocorticoids
Deficiency of glucocorticoids and mineralcorticoids
Glucocorticoids increase the availablity of ____ and the most common hormone is ____.
glucose
Cortisol
What do mineralcorticoids do?
Promote Sodium reabsorption and secretion of potassium and hydrogen
What is the common mineralcorticoid?
Aldosterone
What are the drugs used in Cushing's Syndrome?
Aminoglutethimide
Ketoconazole
What do aminoglutethimide and ketoconazole do?
Inhibit corticosteroid synthesis
What is the treatment of Addison's disease?
Replacement therapy with hydrocortisone
What is the problem in Congenital Adrenal Hyperplasia?
Amounts of ACTH are large because glucocorticoid production is failing and adrenal androgens amounts become excessive
What is the treatment for congential adrenal hyperplasia?
Hydrocortisone
What structure is hydrocortisone similar to?
Cortisol
Hydrocortisone and Fludrocortisone have both ___ and __ actions.
glucocorticoid
mineralcorticoid
Fludrocortisone is a ____.
Potent mineralocorticoid
What drugs mimic the effects ACTH?
Corticotropin
Cosyntropin
What are corticotropin and cosyntropin used for?
Diagnostic Tests
What drug has only glucocorticoid properties?
Dexamethasone