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10 Cards in this Set
- Front
- Back
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Class
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Antidysrhythmic
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Mechanism of Action
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Slows conduction through the AV node; can interrupt re-entrant pathways; slows heart rate by acting directly on the sinus pacemaker cells by slowing impulse formation. The drug of choice for re-entry SVT. Can be used diagnostically for stable, wide complex tachycardia of unknown origin after 2 doses of lidocaine
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Indications
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Conversion of PSVT to sinus rhythm. May convert re-entry SVT due to Wolff-Parkinson-White syndrome. Not effective in converting a-fib/flutter or V-tach. Most forms of stable narrow-complex SVT.
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Contraindications
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2nd or 3rd degree AV block (if no pacemaker present), sick sinus syndrome (if no pacemaker present), bronchoconstrictive or bronchospastic lung disease (asthma, COPD), poison or drug induced tachycardia
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Adverse reactions/ side effects
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generally short duration and mild headache, dizziness, dyspnea, bronchospams, dysrhthmias, palpitation, hypotension, chest pain, facial flushing, cardiac arrest, nausea, metallic taste, pain in the head or neck, paresthesia, diaphoresis
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Drug Interactions
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Methlxanthines, antagonize the effects of adenosine. Dipyridamole potentiates the effect of adenosine. Cabamazepine (tegretol) may potentiate the AV node blocking effect of adenosine.
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How supplied
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3 mg/mL in 2-mL and 5 mL flip flop vials
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Dosage and Admin
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Adult: 6 mg rapid IV bolus over 1-3 seconds, followed by a 20 ml saline flush and elevate extremity. If no response after 1-2 minutes, administer second dose of 12 mg rapid Iv bolus over 1-3 seconds.
Pedi-initial dose .1mg/kg rapid IV/IO push, followed by a 5-10 ml saline flush. Second dose .2 mg/kg rapid IV/IO push followed by 5-10 ml saline flush |
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Duration of action
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Onset:seconds
Peak effect: Seconds Duration: 12 seconds |
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Special Considerations
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Pregnancy safety: Cat. C. May cause bronchconstriction in asthma pt. Evaluate elderly for signs of dehydration requiring fluid replacement prior to administering adenosine. Short half life limits side effects in most pt.
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