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108 Cards in this Set

  • Front
  • Back

Barbiturate half life

10-40hrs, to 50-120hrs

4 types of Barbiturates

Pheno, Amo, Pento, and Secobarbitual

Phenobarbital

long acting

Amobarbituate

Intermediate

Pentobarbitate and Amo are...?

Short acting

What kind of acid is barb derived from

Barbiturate acid

How are barbs drugs used?

As a sedative hypnotic, or anti epileptic medicine

What do bars look like, taste like?

Odorless, colorless, tasteless

How do barbs effect CNS

slows it down, slows down neural activity

Acute effects of barbiturates

Relaxant, death/coma, overdose, sedative effects, drowsy, helps insomnia patients, lowers regions of brain connected with arousal, REM Rebound effect, high synergistic effect when used W other drugs

Chronic effects of barbs

Need higher dosage bc pharmacological tolerance, withdrawal is strong/physical dependence, 5% death when people withdrawal without supervision

Non Barb Sedative Hypnotics? Name the 3

Chloral hydrate


methalaquone


meprobamate

Chloral Hydrate

once treated insomnia


now date rape drug


bad in combo w other drugs


irritates stomach

Methalaquone

Also date rape


Once used for sleeping pills


Schedule 1: has no medical benefits

meprobamate

high toxic dose


first anti anxiety drug to be marketed as treating anxiety


schedule 4: limit on prescriptions


physical and psychological dependence


but worked for people


dangerous to drive w

Benzos

family of anti anxiety drugs

Benzos

family of anti anxiety drugs

Brand names of benzos

diazepam / Valium


Librium


hacion

Benzos

family of anti anxiety drugs

Brand names of benzos

diazepam / Valium


Librium


hacion

Acute effects of benzos

higher level of safety compared to barbs


respirator centers NOT effected so rare to die


but side effect: can lead to dementia if used a lot in elderly

Benzos

family of anti anxiety drugs

Brand names of benzos

diazepam / Valium


Librium


hacion

Acute effects of benzos

higher level of safety compared to barbs


respirator centers NOT effected so rare to die


but side effect: can lead to dementia if used a lot in elderly

Benzo half life

10 days


2 months for elderly

Benzos

family of anti anxiety drugs

Brand names of benzos

diazepam / Valium


Librium


hacion

Acute effects of benzos

higher level of safety compared to barbs


respirator centers NOT effected so rare to die


but side effect: can lead to dementia if used a lot in elderly

Benzo half life

10 days


2 months for elderly

chronic effects of benzos

dependence with withdrawal


anxiety can worsen before getting better


insomnia, agitation, restless

Benzos

family of anti anxiety drugs

Brand names of benzos

diazepam / Valium


Librium


hacion

Acute effects of benzos

higher level of safety compared to barbs


respirator centers NOT effected so rare to die


but side effect: can lead to dementia if used a lot in elderly

Benzo half life

10 days


2 months for elderly

chronic effects of benzos

dependence with withdrawal


anxiety can worsen before getting better


insomnia, agitation, restless

how long is a benzo withdrawl

usually 1-4 weeks


less severe than barbs

how do benzos work In the brain

inhibits GABA


attached to GABA receptor on membrane of neurons and heighten effect of GABA

how are benzos misused

alcoholics take it to reduce withdrawal


benzos have slow onset

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

GHB risks

CNS depressant


thought to b used for steroidal effects


now underground drug / lab

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

GHB risks

CNS depressant


thought to b used for steroidal effects


now underground drug / lab

ghb acute effects

euphoric


out of body experience


date rape: colorless etc


unconsciousness

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

GHB risks

CNS depressant


thought to b used for steroidal effects


now underground drug / lab

ghb acute effects

euphoric


out of body experience


date rape: colorless etc


unconsciousness

Inhalants and history of them


how used today

Greece limestone faults had ethylene gas



today in many products


nitrous oxide, ether

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

GHB risks

CNS depressant


thought to b used for steroidal effects


now underground drug / lab

ghb acute effects

euphoric


out of body experience


date rape: colorless etc


unconsciousness

Inhalants and history of them


how used today

Greece limestone faults had ethylene gas



today in many products


nitrous oxide, ether

Nitrous oxide

1800s England laughing gas


alcoholic replacement


used as anesthetic used


1960s rec use

Nonbenzo depressants


Good for what

better chance for sleep disorders and anxiety

what r whippets?


effects?

canisters w pressurized NO2


euphoria last few minutes


causes nausea, unconsciousness if too much

Ambien/ non benzo depressant

most abused drug


binds to GABA


good for short term insomnia


sedative

Lunesta treats what

insomnia

BuSpar

shows no cross tolerance


less dangerous side effects


relieves anxiety w/o feeling sedative


does not effect GABA Instead effects subclass of seretonin


CONS: long delay to kick in

Beta blockers


name 3


used for what

tenormin, lopressor, inderal


- slows heart rate, relaxes pressure of walls on blood vessels, decreases heart contractions

Anti depressants


name 2


does what?

Paxil Zoloft


treats panic disorder PTSD social anxiety


SSRIs

GHB risks

CNS depressant


thought to b used for steroidal effects


now underground drug / lab

ghb acute effects

euphoric


out of body experience


date rape: colorless etc


unconsciousness

Inhalants and history of them


how used today

Greece limestone faults had ethylene gas



today in many products


nitrous oxide, ether

Nitrous oxide

1800s England laughing gas


alcoholic replacement


used as anesthetic used


1960s rec use

Ether

resembles alcohol intoxication


flammable

dangerous of inhalants

health hazard, choking cardiac sudden death


recklessness destructive behavior


delusions

dangerous of inhalants

health hazard, choking cardiac sudden death


recklessness destructive behavior


delusions

who uses inhalants the most

4th most used drug by middle schoolers