Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
425 Cards in this Set
- Front
- Back
|
Two beta blockers approved for treatment of heart failure
|
Metoprolol succinate and carvedilol
|
|
|
This class of antiarrythmic drug decreases mortality in CHF patients
|
Beta blockers
|
|
|
EKG often shows an usual RBBB in this genetic syndrome that predisposes to sudden cardiac death
|
Brugada syndrome
|
|
|
It is what CRT-D stands for
|
Cardiac Resynchronization therapy Defibrillator
|
|
|
The epsilon wave has been classically decried in patients with this congenital syndrome
|
Arrhymogenic right ventricular dysplasia
|
|
|
This is the number needed to treat with a relative risk reduction of 50% and absolute risk reduction of 12.5 %
|
8
***(1/Absolute Risk Reduction) |
|
|
Using a normal albumin as 4, this is the corrected calcium for a serum Calcium of 7.4 and albumin of 2
|
9
***Corrected Calcium = (0.8 * (Normal Albumin - Pt's Albumin)) + Serum Ca |
|
|
This is the LDL cholesterol in a patient with total cholesterol of 190, HDL of 90 and TG of 50
|
90
****Friedewald (1972) Formula: LDL = TC - HDL - TG/5.0 |
|
|
Positive liklihood ratio with a sensitivity of 0.8 and a specificity of 0.2
|
1
*****Positive Likelihood Ratio= (sensitivity)/(1-specificity) |
|
|
Stool osmotic gap with a stool osmolality of 300, stool sodium of 20 and potassium of 80
|
100
****300(or stool osmolality) − 2 *(stool Na + stool K) >100 suggests osmotic (celiac, lactase deficiency, chronic pancreatitis |
|
|
Eponymous name for antiphospholipid syndrome
|
Hughes syndrome
|
|
|
Testing for antiphospholipid syndrome includes lupus anticoagulant and these two antibodies
|
Beta-2 microglobulin and anticardiolipin antibodies
|
|
|
It is the eponymous name for CAPS (catastrophic antiphospholipid syndrome)
|
Asherson's syndrome
|
|
|
Name of classification for APS
|
Modified/updated sapporo
|
|
|
The association of antiphospholipid antibodies with livedo reticularis and recurrent strokes is known as this
|
Sneddon's syndrome
|
|
|
Drug used to cause muscle relaxation in neuroleptic malignant syndrome
|
Dantrolene
|
|
|
Hydrochlorothiazide plus triamterene
|
Diazide
|
|
|
Anti-thrombin inhibitor thats begins with "D"
|
Dabigitran
|
|
|
Drug that beings with "D" and is an anti-thrombin inhibitor
|
Dabigatran (Pradaxa)
|
|
|
Drug starting in "D" that may cause elevated CPK and is inhibited by surfactant
|
Daptomycin
|
|
|
Drug starting with "D" that is a class III antiarrythmic
|
Dofetilide
|
|
|
This form of warfarin is most potent
|
S- warfarin
|
|
|
Factor Xa inhibitor recently shown to be non-inferior to warfarin in stroke prevention in atrial fibrillation
|
Rivaroxaban
|
|
|
This gene plays an important roe in metabolizing s-warfarin to its inactive form
|
CYP2C9
|
|
|
This gene is important in the production of active warfarin
|
VKORC1
|
|
|
It is was "WARF" in warfarin stands for
|
Wisconsin Alumni Research Foundation
|
|
|
Esophagitis in HIV with multinucleated giant cells on histology
|
HSV
|
|
|
This virus has been associated with multicentric castlema disease in HIV patients
|
HHV-8
|
|
|
Steroids added to PCP treatment in these two situations
|
pa02 <70 or A-a gradients >35
|
|
|
Test that must be don before starting maraviroc
|
viral tropism assay
|
|
|
Screening test for hypersensitivity to abacavir
|
HLA B-5701
|
|
|
Name of syndrome associated with hypokalemic periodic paralysis and long QT7
|
Anderson-Tawil Syndrome
|
|
|
The CAM score used for estimation of severity of malaria stands for this
|
Coma Acidosis Malaria
|
|
|
Drug very active against falciparum believed to produce free radicals in the parasite food vacuole
|
Artesunate, artemisinins
|
|
|
Malaria may be cause by pasmodium vivax, malriae, falciparum and these two others
|
Ovale and knowlesi
|
|
|
Malarone is a combination of atovaquone and this drug
|
Proguanil
|
|
|
CAM score uses bicarbonate score, respiratory rate score and these two factors
|
Base deficit and GSC
|
|
|
Polyglandular syndrome 1 include hypoparathyroidism, addison's disease and this
|
Mucocutaneous candidiasis
|
|
|
Terbinafine inhibits this enzyme
|
Squalene epoxidase
|
|
|
Caspofungin and micafungin belong to this class of drugs
|
Echinocandins
|
|
|
Hyper IgE sydrome associated with mucocutaneous candidiasis
|
Job syndrome
|
|
|
Candida species with strong affinity for plastic that has a shaggy, spider-like appearance on sabouraud's agar
|
Candida parapsilosis
|
|
|
Syndrome of Cafe Au lait spots, polyostotic fibrous dysplasia and endocrine dysfunction
|
McCune-Albright syndrome
|
|
|
Acromegaly like condition where patients have normal IGF-1 and insulin resistance
|
Pseudoacromegaly
|
|
|
Drug used to inhibit growth hormone
|
Pegvisomant
|
|
|
Three components of MEN IIA Sydrome
|
Medullary thyroid cancer, Pheochromocytoma, Hyperparathyroidism/Parathyroid hyperplasia
|
|
|
Drug starting in "R" was is used in treatment of Tumor Lysis Syndrome
|
Rasburicase
|
|
|
Drug starting with "R" that is an integrase inhibitor (anti-viral medication developed for use in HIV)
|
Raltegravir
|
|
|
Drug starting in "R" used in treatment of Alzheimer's disease
|
Rivastigmine
|
|
|
Drug starting in "R" that is a SERM
|
Raloxifene
|
|
|
Sildenalfil has been marketed for pulmonary hypertension as this brand name (begins with "R")
|
Revatio
|
|
|
Patients with hyperplastic polyps should be screened within this time
|
10 years
|
|
|
Other than Heme-Occult testing, these other two stool tests can be used in screening
|
Stool DNA and feval immuno-chemical testing (FIT)
|
|
|
Patients with sessile polyps removed piecemeal should have repeat colonoscopy within this time
|
6 months
|
|
|
Patients with 3-10 polyps should be screened after this many years
|
3 years
|
|
|
patients with >1cm adenoma or adenomas with villous features or high grade dysplasia should be screened within this time
|
3 years
|
|
|
Syndrome where jaundice results from erosion of a gallstone through the gallbladder wall, compressing the common hepatic duct
|
Mirizzi syndrome
|
|
|
Lead intoxication may lead to this type of gout
|
Saturnine
|
|
|
This vaccine has been used to prevent bladder cancer
|
BCG vaccine
|
|
|
Drug of choice for treatment of MDS with 5Q deletion
|
Lenalidomide
|
|
|
Aggrenox is comprised of 200mg dipyridamole and this much aspirin
|
25mg
|
|
|
Name of this syndroe is associated with hypokalemic periodic paralysis and long QT7
|
Anderson-Tawil syndrome
|
|
|
Stress fracture associated with CKD and normal PTH, caused by excess vitamin D intake
|
Adynamic bone disease
|
|
|
This type of RTA is associated with an alkaline urine PH
|
Type 1 -Distal
|
|
|
Drug used to decrease risk of uric acid stones
|
Potassium citrate
|
|
|
It is what CVVH stands for
|
Continuous venovenous hemofiltration
|
|
|
Drug starting in "P" which when given in an aerosolized form can be used to PCP prophylaxis in HIV
|
Pentamidine
|
|
|
Drug beinnging with "P" that is part of four drug TB regimen
|
Pyrazinamide
|
|
|
Drug beginning with "P" used for treatment of Toxoplasmosis
|
Pyrimethamine
|
|
|
FDA approved in 2009 this statin goes by the brand name livalo
|
Pitastatin
|
|
|
Drug beginning with "P" that is growth hormone inhibitor
|
Pegvisomant
|
|
|
Only FDA approved drug for weight loss
|
Orlistat (Xenical)
|
|
|
Bisphosphonates inhibit the effect of osteoporosis treatment drug
|
Teriparatide
|
|
|
This drug is preferred over bromocriptine as the first ling treatment of prolactinomas
|
Cabergoline
|
|
|
Syndrome that occurs 7-10 days after neursurgical procedures presenting with hyponatremia and hypotension
|
Cerebral salt wasting
|
|
|
Lupus was derived from the latin word for this
|
Wolf
|
|
|
Presence of these antibodies in a pregnant mother increased the risk of congenital complete heart block
|
Anti-Ro and Anti-La
|
|
|
Human Monoclonal antibody targeting RANK-L was FDA approved for osteoporosis in June 2010
|
Denosumab
|
|
|
Human monoclonal antibodies FDA approved in March 2011 for treatment of SLE
|
Belimumab
|
|
|
AML with DIC is associated with this translocation
|
t(15:17) all trans retinoic acid
|
|
|
Direct thrombin inhibitor used for HITT that is eliminated by the kidneys
|
Lepirudin
|
|
|
Two of three tyrosine kinase inhibitors approved for CML treatment
|
Imatinib, dasatinib, or nilotinib
|
|
|
Drug used to treat MDS associated with deletion of long arm of chromosome 5
|
Lenalidomide
|
|
|
Diagnosis of Creutzfeld Jakob disease by biopsy of brain or this
|
Tonsils
|
|
|
First line treatment for narcolepsy
|
Modafinil
|
|
|
Assessment for need of steroid in alcoholic hepatitis is determined by this blood test
|
Carbohydrate free transferrin
|
|
|
Treatment of scleroderma renal crisis in pregnancy
|
ACE-inhibitor
|
|
|
Protein that may be found in CSF of CJD
|
14-3-3 protein
|
|
|
Monoclonal antibody used in the treatment of paroxysmal nocturnal hemoglobinuria
|
Eculizimab
|
|
|
Acidosis in Type 2 RTA results from this
|
Decreased bicarbonate absorption
|
|
|
This type of renal tubular acidosis causes an alkaline urine PH
|
Type 1
|
|
|
Autoimmune diseases are likely to be associated with which type of RTA
|
Type 1
|
|
|
Use of TMP-SMX is likely to cause this type of RTA
|
Type 4
|
|
|
Calcium-Phospahte should be less than this
|
55
|
|
|
Sevalemer and lanthanum are both these types of drugs
|
Phosphate binders
|
|
|
Nephropathy associated with Hodgkin's lymphoma
|
Minimal change disease
|
|
|
Histological cause of renal artery stenosis in persons <40
|
Fibromuscular dysplasia
|
|
|
Cyst-like brown tumors secondary renal osteodystrophy
|
Osteititis cystica fibrosa, von recklinhausen's disease
|
|
|
Condition associated with intestinal bacterial overgrowth
|
Scleroderma
|
|
|
Two antibodies associated with autoimmune hepatitis
|
ANA, Smooth muscle, LKM, SLA
|
|
|
Extremely rare syndrome associated with mechanics hands, myositis, arthritis and interstitial lung disease
|
Antisynthetase syndrome
|
|
|
3 skin findings found in dermatomyositis
|
Gottron's papulres, shawl sign, heliotrope rash, erythroderma
|
|
|
Meltzer's triad of cryoglobulinemia comprises arthralgia, myalgia and this
|
Purpura
|
|
|
Obstruction of Meibomian tear gland
|
Chalazion
|
|
|
Disease associated with iris hamartomas and optic gliomas
|
Neurofibromatosis
|
|
|
Presence of this in wet age related macular degeneration differentiates it from dry
|
Neovascularization
|
|
|
Eye condition that has been associated with acute pancreatitis
|
Putcher's retinopathy
|
|
|
Damage to Meyer's loop of the right temporal lobe would lead to this visual defect
|
Left superior quadrant anopsia
|
|
|
Iodine induced hypothyroidism is referred to as this
|
Wolff-Chaikoff effect
|
|
|
Name for clubbing appearance of the fingers in Graves disease
|
Thyroid acropachy
|
|
|
Blunted symptoms of thyrotoxicosis in elderly
|
Apathetic hyperparathyroidism
|
|
|
Selective estrogen modulator (SERM) used in treatment of Reidel's thyroiditis
|
Tamoxifen
|
|
|
Sustained hand grip classically increases the intensity of this murmur
|
Mitral Valve Prolapse
|
|
|
This refers to the common finding of an apical murmur in a very elderly person who has aortic stenosis
|
Gallavardin phenomenom
|
|
|
Blow to the chest resulting in arrythmia and sudden cardiac death
|
Commotio cordis
|
|
|
Causes of pulsus alternans
|
Left ventricular dysfunctions
|
|
|
The recent re-ly trial showed that this drug was non-inferior to warfarin in preventing strokes in atrial fibrillation
|
Dabigatran
|
|
|
AML M5 classically associated with this
|
Gingival hyperplasia
|
|
|
A patient with CLL Stage III must have this
|
Anemia
|
|
|
Findings on flow cytometry in PNH
|
Decreased CD55 and CD 59
|
|
|
Common side effect of the multiple myeloma drug Bortezomib
|
Peripheral Neuropathy
|
|
|
Dementia associated with Visual Hallucinations
|
Lewy Body Dementia
|
|
|
Two drugs that can be used for treatment of of meningococal exposure
|
Rifampin and Ciprofloaccin
|
|
|
Electrical shock sown spine of bending beck forward in multiple sclerosis or cervical spondylosis
|
Lhermitte sign
|
|
|
CSF test used for Creutzfeldt-Jakob Disease
|
14-3-3
|
|
|
Recurrent Benign aseptic meningitis secondary to HSV
|
Mollaret's meningitits
|
|
|
Drug begninng with "E" used to treat rheumatoid arthritis
|
Etanercept or ENBREL
|
|
|
Drug beginning with "E" that is a an incretin mimetic
|
Exanitide
|
|
|
Drug beginning with "E" that is an HIV protease inhibitor
|
Efavirenz
|
|
|
Drugs beginning with "E" used to treat von willibrand's disease
|
Estrogen
|
|
|
Treatment beginning with "E" that is used for treatment of intravascular hemolysis in PNH
|
Eculizumab
|
|
|
Parasite associated with increased risk of bladder cancer
|
Schistosomiasis
|
|
|
Viral Load required in HIV to start HAART
|
>55,000
|
|
|
Bifid pulse is seen in these two conditions
|
HCM and Aortic Stenosis
|
|
|
Rapid X Descent
|
Tamponade
|
|
|
Blood supply for the AV node
|
RCA
|
|
|
Regular cannon A waves is seen in this condition
|
AVNRT/TS
|
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
|
Autoimmune hemolytic anemia + ITP
|
Evans syndrome
|
|
|
Gingivial Hyperplasia is seen with this type of leukemia
|
AML M5 (monocytic subtype
|
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
|
Cigar/Pencil shaped RBC is seen on PS in this condition
|
Iron Deficiency
|
|
|
Genetic cause of SCD with RBBB and ST Elevation in V1-V3
|
Brugada syndrome
|
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
|
Cigar/Pencil shaped RBC is seen on PS in this condition
|
Iron Deficiency
|
|
|
Factor Deficiency seen in amyloidosis
|
Factor X
|
|
|
Commonest cause of deaht in rheumatoid arthritis
|
Coronary Artery Disease
|
|
|
Mixed connective tissue diseases is a mix of these three
|
SLE, polymyositis, and systemic sclerosis
|
|
|
2 diseases commonly associated with pseudo gout
|
Hemochromatosis and hyper parathyroidism
|
|
|
DMARD with similar action and S/E profile with methotrexate
|
Leflunomide
|
|
|
This type of vasculitis causes HTN secondary to RAS
|
Takayasu arteritis
|
|
|
Hepatitis B can be treated with Lamivudine and this drug
|
Tenofovir, adefovir, entecavir
|
|
|
Xanthine oxidase inhibitor other than allopurinol
|
Febuxostat
|
|
|
Colchicine was FDA approved treatment of gout in this year
|
2009
|
|
|
Numbness and pain in 3rd and 4th metatarsals secondary to this benign neuroma
|
Morton's Neuroma
|
|
|
C-ANCA immunoflourescene pattern is commonly associated with antibodies to this
|
Proteinase-3
|
|
|
Audible click on pressing two metatarsal heads together in morton's neuroma is known as this sign
|
Mulder's sign
|
|
|
PAS positive macrophages on intestinal biopsy
|
Whipple's disease
|
|
|
Organism associated with undercooked pork that can result in severe diarrheal syndrome
|
Yersinia enterolitica
|
|
|
Gene and chromosome associated with familial adenomatous polyposis
|
APC gene on long arm of chromosome 5
|
|
|
Erosion of large tortuous arteriole in stomach
|
Dieulafoy's lesion
|
|
|
Hyperplastic hypersecretory gastropathy presenting with postprandial pain and albumin loss
|
Menetrier's disease
|
|
|
What is winter's formula
|
PC02= 1.5(HC03) +8 +/- 2
|
|
|
Ingestion of this can cause ketonemia without acidosis
|
Isopropyl alcohol
|
|
|
Indications for steroids in PCP infection
|
paO2 < 70 or A-a gradients >35
|
|
|
Formula for alveolar P02
|
(Fi02 x713) - (PaCO2 x1.2)
|
|
|
Suboxone is a combination of buprenorphine and this drug
|
Naloxone
|
|
|
Beta-blocker starting with "N" with powerful vasodilatory effect
|
Nebivolol
|
|
|
Insulin secretagogue marketed as starlix
|
Nateglinide
|
|
|
Drug starting with "N" used to treat multiple sclerosis
|
Natalizumab
|
|
|
Treatment of Philadelphia chromosome positive CMP
|
Nilotinib
|
|
|
Topical cream used in treatment of genital warts
|
Podophyllin or imiquimod
|
|
|
Esophageal biopsy in HIV showing owl's eye inclusions
|
CMV esophagitis
|
|
|
Cause of diarrhea occurring while patient on cruise ship
|
Norwalk virus
|
|
|
This antiviral agent used for treatment of influenza may cause bronchospasm
|
Zanamivir
|
|
|
Formula for non-LDL cholesterol
|
Total cholesterol - HDL
|
|
|
Lipid lowering drug indicated for treatment of diabetes
|
Colesevelam
|
|
|
Omega 3 Fatty Acids reduce triglycerides but increase in lipoprotein
|
LDL
|
|
|
Lipid lowering drug that decreased insulin sensitivity
|
Niacin
|
|
|
In the Friedewald equation, VLDL is equal to this
|
Triglycerides divided by 5
|
|
|
Syndrome characterized by finger agnosia and dyscalcula
|
Gerstman syndrome
|
|
|
Name of maneuver used to reverse benign positional vertigo
|
Epley's maneuver
|
|
|
Inflammatory disease similar to multiple sclerosis causing episodic optic neuritis and myelitis
|
Neuromyelitis optica (NMO) or Devic's disease
|
|
|
FDA approved in 2010 this drug improves walking in multiple sclerosis
|
Fampridiine SR (AMPYRA)
|
|
|
This stage of sleep involves sleep spindles and K complexes
|
Stage 2
|
|
|
Positive liklihood ratio with a sensitivity of 0.8 and specificity of 0.6
|
2
|
|
|
Centor criteria include fever, absence of cough and these two
|
Tonsillar exudate, tender cervical lypmhadenopathy
|
|
|
Eponymous name for uveoparotid syndrome in sarcoidosis
|
Heerfordt's syndrome
|
|
|
Blood pressure greater in legs vs arms in aortic regurgitation known as this sign
|
Hill sign
|
|
|
Blue toes post-angiography secondary to this
|
cholesterol emoblism
|
|
|
EGFR inhibitor used in treatment of k-ras wild-type colorectal cancer
|
Cetuximab
|
|
|
Drug starting with "F" that is a xanthine oxidase inhibitor
|
Febuxostat
|
|
|
Treatment for CLL
|
Fludarabine
|
|
|
Drug used as antidote for ethylene glycol intoxication
|
Fomepizole
|
|
|
Drug starting with "F" ndicated in hypertensive emergency
|
Fenoldopam
|
|
|
Antiandrogen drug beginning with "F" used to treat prostate cancer
|
Flutamide
|
|
|
Multiple myleoma drug that increases risk of DVT
|
Thalidomide
|
|
|
White blood cell with bi-lobed Dumbbell
|
Pelger-Huet cell
|
|
|
Activated protein C used in treatment of sepsis also called this
|
Drotecogin alfa
|
|
|
Management of persons exposed hepatitis
|
Hepatitis A immunoglobuliin
|
|
|
Other than neomycin this antibiotic is approved for treatment and prevention of hepatic encephalopathy
|
Rifaximin
|
|
|
Reynold's pentad for septic ascending cholangitis includes fever, abdominal pain, jaundice and these two
|
Hypotension and altered mental status
|
|
|
Type of recurrent cholangitis occuring in southeast asia
|
Oriental cholangitis
|
|
|
Cholangiocarcinoma at junction between left and right hepatic ducts
|
Klatskin tumor
|
|
|
Rare syndrome assocaited with mechanic's hands, myositis, arthritis and interstitial lung disease
|
Antisynthetase syndrome
|
|
|
Mcmurray test positive with this injury to this part of the knee
|
medical meniscus
|
|
|
Lachman's test positive with damage to this part of the knee
|
Anterior Cruciate ligament
|
|
|
Arthritis mutilans is classically associated with this type of arthritis
|
Psoriatic arthritis
|
|
|
HLA-B5701 screening should be done to present hypersensitivity to this drug
|
Abacavir
|
|
|
This HIV drug has been notorius for causing nightmares
|
Efavirenz
|
|
|
The protuberant crixivan belly associated with HIV lipodystrophy was named after the brand name for this drug
|
Indinavir
|
|
|
Atripla is a combination of emtracitabine and these two medications
|
Efavirenz and tenofovir
|
|
|
It is what the "I" in folfiri stands for in relation to treatment of colorectal cancer
|
Irinotecan
|
|
|
Most common cause of heel pain
|
Plantar fascitis
|
|
|
Autoantibody associated with absence of interstitial lung disease in patients with scleroderma
|
Anti-centromere antibody
|
|
|
Autoantibody assocaited with mixed connective tissue disease
|
Anti-U1-RNP
|
|
|
Autoantibody associated with myositis, interstitial lung disease, arthritis and a hyperkeratotic rash on the hands
|
antihistidyl-tRNA synthetase
|
|
|
Name four of the five major jones criteria for the diagnosis of rheumatic fever
|
Carditis,sydenham's chorea, polyarthrititis, EM, SC nodules
|
|
|
Watery diarrhea, hypokalemia, achlorhydria, and acidosis
|
VIPoma
|
|
|
Commonest cause of adrenal insufficiency
|
Iatrogenic glucocorticoids
|
|
|
Production is increased in sarcoidosis and contributes to hypercalcemia
|
1,25-dihydroxycholecalciferol
|
|
|
This drug stimulates new bone formation by increasing osteoblast activity
|
Teriparatide or Recombinant human PTH
|
|
|
Internuclear opthalmoplegia is a lesion of this structure
|
Medical longitudinal fasiculus
|
|
|
The classic findings in Wernicke's encephalopathy
|
Confusion, ataxia, ophthalmoplegia
|
|
|
Acute onset of ipsalateral horner's syndrome, ipsalateral face and contralateral body sensory deficit
|
Wallenberg's syndrome
|
|
|
The other name of relative afferent pupillary defect
|
Marcus-Gunn pupil
|
|
|
Syndrome characterized by frequent falls and vertical gaze paralysis
|
Progressive supranuclear palsy
|
|
|
The commonest glomerulonephritis in the world
|
IgA nephropathy
|
|
|
Syndrome characterized by joint pain, abdominal pain, palpable purpura and nephritic sediment
|
Henoch-Scholein purpura
|
|
|
In addition to RBC casts, this microscopic finding supports diagnosis of glomerulonephritis
|
Dysmorphic RBC
|
|
|
This hematological lab finding in CKD is an independent risk predictor of LVH
|
Anemia
|
|
|
This syndrome is caused by inactiving mutation of loop diuretic sensitive channel in the kidney
|
Bartter's syndrome
|
|
|
This substance is a major health hazard for children in old house
|
Lead
|
|
|
Medical treatment for mild to moderate salicylate intoxication
|
Urinary alkalinization
|
|
|
Antidote for calcium channel blocker toxicity
|
Calcium
|
|
|
EtOH poisoning associated with increased osmolar gap but a normal anion gap
|
Isopropyl alcohol
|
|
|
Drug for nerve gas exposure that reactivates acetylcholine esterase
|
Pralidoxime
|
|
|
Mention at least 2 auscultatory findings associated with acute disappears with relief of ischemia
|
Murmur of MR, S4, S3, paradoxical S2 splitting
|
|
|
Dermatologic condition associated with celiac disease
|
Dermatitis herpetiformis
|
|
|
Inhaled drug effective for bronchoconstriction due to propanolol
|
Ipratoprium
|
|
|
+Kveim-siltzbach test occurs in this disease
|
Sarcoidosis
|
|
|
This medication inhibits the common pathway of platelet aggregation
|
Abciximab, Tirofiban, Eptifibatide
|
|
|
Infection with this parasite can cause portal hypertension
|
Schistosoma mansoni
|
|
|
Organism associated with chronic diarrhea and eosinophilia in AIDS patients
|
Isospora belli
|
|
|
Fever, flu-like symptoms, tachycardia and hypotension developing during treatment of syphilis
|
Jarisch-Herxheimer reaction
|
|
|
The other name of type 2 lepra reaction
|
Erythema nodusum leprosum
|
|
|
Class of this drugs useful in the treatment of influenza A and B infection
|
Neuraminidase inhibitor
|
|
|
The single most important prognostic marker for multiple myeloma
|
B2-microglobulin
|
|
|
Combination of autoimmune hemolytic anemia and ITP
|
Evan's syndrome
|
|
|
A coagulation factor deficiency A coagulation factor deficiency with increased PTT< normal PT, thrombin time, platelet count, bleeding time and no clinical bleeding
|
Factor XII deficiency
|
|
|
Coumadin induced skin necrosis occurs in this disorder
|
Protein C or S deficiency
|
|
|
Severe bleeding with normal PT, PTT, thrombin time, platelet count and bleeding time
|
Factor XIII deficiency
|
|
|
Pulmonary artery occlusion pressure estimates this parameter
|
LVEDP
|
|
|
Name the components of the tetralogy of Fallot
|
RV outflow obstruction, VSD, RVH, aortic override of VSD
|
|
|
LV EF and systolic LV internal diameter used as an indication for surgical intervention in severe mitral regurgitation
|
LVEF <60%
LVID in systole >45 mm |
|
|
Diagnosis associated with equalization of diastolic pressures in RA, RV, PCWP, and LV
|
Tamponade or constrictive pericarditis
|
|
|
Blue sclera, hearing impairment and brittle bones
|
Osteogenesis imperfecta
|
|
|
Inherited disorder with HTN, hypokalemia, alkalosis
|
Liddle's syndrome
|
|
|
Acidosis, aminoaciduria, phosphaturia and glycosuria
|
Fanconi's syndrome
|
|
|
Gastrointestinal polyps and pigmented macules around mouth and lips
|
Peutz-jeghers' syndrome
|
|
|
Hypogonadic gonadism, anosmia, and color blindness
|
Kallman syndrome
|
|
|
This cancer isa ssociated with overproduction of calcitonin
|
Medullary carcinoma of the thyroid
|
|
|
Most common malignancy in humans
|
Skin cancers
|
|
|
A relapsing rever associated with hodgkin's disease
|
Pel-ebstein fever
|
|
|
Test used to screen for anal intraepithelial neoplasia in high risk individuals
|
Anal pap smear
|
|
|
A patient with SCLC presenting with subacute onset of confusion memory loss and temporal lobe seizures
|
limbic encephalitis
|
|
|
Infertility, dextrocardia, recurrent respiratory infection
|
Kartagner's syndrome
|
|
|
Treatment of choice for Paget's diseases
|
Bisphosphonates
|
|
|
HSV disease with LMN facial palsy and vesicles in external ear
|
Ramsay-Hunt syndrome
|
|
|
An oral medication approved in 2009 for hypervolumic and euvolemic hyponatremia
|
Tolvaptan/Samca
|
|
|
Syndrome of digital clubbing and chronic proliferative periostitis of long bones seen in lung cancer
|
Pulmonary hyperthrophic osteoarthropathy
|
|
|
First person to see an RBC under a microscope
|
Anton von Leewenhoek
|
|
|
Other than imatinib and dasatinib this tyrosine kinase inhibitor can also be used in treatment of CML
|
nilotinib
|
|
|
Two blood tests used in diagnosis of heparin- induced thrombocytopenia
|
Anti-platelet factor 4 and serotonin release assay
|
|
|
Stage IV CLL may have anemia, lymphadenopathy ad HSP but must have this
|
Thrombocytopenia
|
|
|
Proteosome inhibitor used in treatment of multiple myeloma
|
Bortezomib
|
|
|
Von-willebrand's factor cleaving protease that is often inhibited
|
ADAMTS-13
|
|
|
This condition may result form gadolinium administration in patient with impaired renal function
|
Nephrogenic systemic sclerosis
|
|
|
Urine anion gap in renal tubular acidosis in this
|
Positive
|
|
|
Valvular defect common in polycystic kidney disease
|
Mitral valve prolapse
|
|
|
Two drugs used in treatment of Wegener's granulomatosis
|
Cyclophosphamide and steroids
|
|
|
This bacterial cause of pneumonia has been associated with stevens-johnsons syndrome
|
Mycoplasma pnuemoniae
|
|
|
Black pleural effusion
|
Aspergilosis nigricans
|
|
|
The antibiotic for treatment of VRE is inhibited by surfactant and should not be used to treat pneumonia
|
Daptomycin
|
|
|
The brand-name for the drug advair comprises these two drugs
|
Salmeterol and fluticason
|
|
|
Other than TMP-SMX two other drugs that can used as PCP prophylaxis in HIV patients
|
atovaquone, dapsone, aerosol pentamidine
|
|
|
Two main serological tests for celiac disease
|
anti-endomysial and anti-tissue transglutaminase antibody
|
|
|
Two serological tests used to diagnose pernicious anemia
|
Anti-parietal cell and anti-intrinsic factor
|
|
|
Posterior uveitis is associated with this malabsorption syndrome
|
Whipple's disease
|
|
|
Drug used to treat dermatitis herpetiformis
|
Dapsone
|
|
|
Pendular oscillations of the eyes with simultaneous masticatory contraction in Whipple's disease
|
Oculomasticatory myorrhythmia
|
|
|
Urate crystals appear this color when parallel to polarized light
|
Yellow
|
|
|
Ulnar deviation of the fingers resembling rheumatoid arthritis seen in SLE
|
Jaccoud's arthropathy
|
|
|
Use of this drug in psoriatic arthritis may actaully worsen psoriatic rash
|
Hydroxychloroquine
|
|
|
p-anca immunofluorescene pattern is commonly associated with antibodies to this
|
Myeloperoxidase
|
|
|
Syndrome of rheumatoid arthritis with pneumoconiosis
|
Caplan's syndrome
|
|
|
Coccidiodes immitis has been associated with this rash
|
Erythema nodosom
|
|
|
This virus has been associated with Kaposi sarcoma
|
HHV-8
|
|
|
First person to see RBC with a microscope
|
Anthony Van Leewenhoek
|
|
|
Seizures starting with laughter are referred to as this type of epilepsy
|
Gelastic epilepsy
|
|
|
Raising arms above head in SVC syndrome causing facial flushing is known as this sign
|
Pemberton's sign
|
|
|
Management of small cell cancer does not involve this
|
Surgery
|
|
|
Two chemotherapeutic drugs usually used for small cell cancer
|
Paclitaxel and etoposide
|
|
|
Polyuria and polydipsia commonly associated with this type of lung cancer
|
Squamous cell cancer
|
|
|
Contralateral flushing and hypohidrosis of the face in horner's syndrome
|
Harlequin's sign
|
|
|
Mixed metabolic acidosis and respiratory alkalosis with tinnitus
|
Aspirin - salicylates
|
|
|
Drug used for reversal of benzodiazepine overdose
|
Flumazenil
|
|
|
Treatment for methemoglobinemia
|
Methylene blue
|
|
|
Papilledema and retinal hemorrhages
|
Methanol poisoning
|
|
|
One test that will help distinguish intravacular hemolysis from extravascular hemolysis
|
Low haptoglobin
|
|
|
Presence of this feature on CBC represents the worst prognosis in patients with CLL
|
Thrombocytopenia
|
|
|
Feared bone complication of zoledronic acid use
|
Osteonecrosis of the Jaw
|
|
|
Hyposplenism or asplenia may cause the appearance of these on peripheral blood smear
|
Howell-Jolly bodies
|
|
|
Formula for number needed to treat
|
1/Absolute Risk Reduction
|
|
|
Formula for power if given beta error
|
Power = 1- beta
|
|
|
Definition of alpha error
|
Prob of rejecting null hypothesis when it is true
|
|
|
Formula for positive likelihood ratio
|
Sensitivity divided by (1-specificity)
|
|
|
Formula for negative likelihood ratio
|
(1-sensitivity) divided by specificity
|
|
|
Antiseizure Drug beginning with "C" associated with agranulocytosis and SIADH
|
Carbmazepine
|
|
|
Drug beginning with "C" that is a bile acid sequestrant is also used for glycemic control in diabetics
|
Colesevelam
|
|
|
This polymyxin antibiotic is used to treat MDR organisms such a P aeruginosa and Klebsiella
|
Colistin
|
|
|
This D-test is used to detect whether MRSA is truly susceptible to this antibiotic
|
Clindamycin
|
|
|
Treatment for CMV
|
Retinitis
|
|
|
Reversible apical hypokinesis secondary to stressful event
|
Takotsubo cardiomyopathy- broken heart syndrome
|
|
|
Thienopyridine approved in 2009 for treatment of ACS in patients planned for PCI
|
Prasugrel
|
|
|
Anti-arrythmic drug that may cause cinchonism
|
Quinidine
|
|
|
Brugada syndrome and ARVD are associated with an increased risk of this
|
V-fib, Sudden cardiac death
|
|
|
Most antiarrythmics are considered proarrythmic becuase they increase the risk of this
|
Prolonged QT Torsades de pointes
|
|
|
Treatment of first degree AV block in Lyme disease
|
Doxycycline or amoxicillin
|
|
|
Treatment of complete AV block
|
Ceftriaxone or Pen G 14-21 Days
|
|
|
Treatment of neurological manifestations
|
IV ceftriaxone, Pen G or doxycycline x 14 days
|
|
|
Treatment of Bell's Palsy in Lyme's disease
|
Doxycycline or amoxicillin
|
|
|
Stage 3 Lyme disease skin condition to due to untreated erythema migrans
|
Acrodermatitis chronica atrophicans
|
|
|
Drug starting with "V" that is an angiotensin receptor blocker
|
Valsartan
|
|
|
Drug starting with "V" that is used to treat bipolar disorder
|
Valproic acid
|
|
|
Drug that starts with a "V" that is used to treat herpes
|
Valacyclovir
|
|
|
Drug that starts with a "V" that is a smoking cessation drug
|
Varenicline
|
|
|
Drug that begins with "V" that is used to treat invasive aspergillosis
|
Voriconazole
|
|
|
This is the most common hereditary coagulation disorder in humans
|
von Willebrand's disease
|
|
|
No change in PT or PTT after mixing study
|
Presence of factor inhibitor
|
|
|
Factor deficiency not associated with excess hemorrhage but associated with prolonged PTT
|
Factor XII (Hageman factor) deficiency
|
|
|
No spontaneous bleeding and normal coagulation profile but often discovered after trauma
|
Factor XIII deficiency
|
|
|
Fibrinogen activity can be assessed using this measurement particularly when there is heparin on board
|
Reptilase
|
|
|
This NNRTI has been associated with birth defects when used during pregnancy
|
Efavirenz
|
|
|
CCR5 inhibitor
|
Maraviroc - Seizentry
|
|
|
Increased cardiovascular risk was demonstrated with the use of this NRTI in the smart study
|
Abacavir
|
|
|
Before starting abacavir patients be screened for this HLA subtype to prevent hypersensitivity
|
B5701
|
|
|
Involuntary lifting of the legs when lifting patients head off bed
|
Brudzinki's sign
|
|
|
Class of drugs associated with aseptic meningitis
|
NSAID's, IV immunoglobulins
|
|
|
Recurrent aseptic meningitis associated with HSV 2
|
Mollaret's meningitis
|
|
|
Post-exposure prophylaxis for meningitis with rifampin or this drug
|
Ciprofloxacin
|
|
|
CSF showing eosinophils in patient eating undercooked snails in a tropical country
|
Angiostrongylus cantonensis
|
|
|
Drug associated with lactic acidosis
|
Linezolid
|
|
|
This drug that is similar to tetracycline used to treat VRE
|
Tigecycline
|
|
|
Not recommended for VRE pneumonia as it is inhibited by surfactant
|
Daptomycin
|
|
|
Hyperreflexia and tremor associated with interaction between SSRI's and this VRE drug
|
Linezolid
|
|
|
Quinopristin and Dalfopristin are not effective for this type of VRE
|
E Fecalis
|
|
|
Anticoagulant used in the treatment of veno occlusive disease of the liver
|
Defibrotide
|
|
|
Cut off value for +PPD for you and me
|
>=10mm
|
|
|
HAART with s/e of hyperbilirubinemia
|
Atazanavir
|
|
|
1st line treatment for aspergillosis
|
Voriconzale
|
|
|
Treatment of babesiosis
|
Quinine-clindamycin/atovaquone
|
|
|
This virus causes spastic paralysis
|
HTLV-1
|
|
|
Egg shell calcification on chest x-ray
|
silicosis
|
|
|
Common cause of pneumonia in patients with CF
|
Psuedomonas
|
|
|
Criteria for ARDS
|
P02/Fi02 <200, BL infiltrates, NL PCWP
|
|
|
Photographic negative of pulmonary edema on chest X-ray
|
Chronic eosinophillic pneumonia
|
|
|
Egg shell calcification on chest xray
|
Silicosis
|
|
|
Short acting beta blocker that started with "E" used in hypertensive emergency
|
Esmolol
|
|
|
Drug with mortality benefit post MI CHF that begins with "E"
|
Epleronone
|
|
|
Drug for treatment of PNH that begins with "E"
|
Eculizumab/ anti C5 antibody
|
|
|
Novel drug for treatment of refractory ITP
|
Eltrombopag
|
|
|
Anticoagulant drug used in treatment of veno occlusive disease of the liver
|
Defibrotide
|
|
|
Serological biomarker that can be positive in Crohns disease
|
ASCA
|
|
|
Organisms with cause AIDS cholangiopathy
|
Cryptosporidium and CMV
|
|
|
This condition gives false negative testing in celiac disease
|
IgA deficiency
|
|
|
Diagnostic test for lactose intolerance
|
Hydrogen breath test
|
|
|
2 important contraindications for TIPS
|
CHF and encephalopathy
|
|
|
Hypovolemic hypoosmolar hyponatremia in patients s/p neurosurgical procedures
|
Cerebral salt wasting
|
|
|
RTA with urine pH >5.5 and hypokalemia
|
Distal/Type 1 RTA
|
|
|
Best ace drug for treatment of scleroderma renal crisis
|
Captopril
|
|
|
Drug used in treatment of resistant hypertension
|
Spironolactone
|
|
|
Treatment of myeloma kidney
|
Chemotherapy and plasmapheresis
|
|
|
Diagnostic aid for avascular necrosis in a patient with a pacemaker
|
Radionuclide bone scan
|
|
|
Commonest cause of osteoporosis in males
|
Hypogonadism
|
|
|
Formular for NNT and ARR
|
NNT=1/ARR, ARR=LE-LP
|
|
|
Two antidepressant with no weight gain side effects
|
Buproprion and venlafaxine
|
|
|
Treatment of acute unilateral hearing loss
|
Steroids
|
|
|
Cause for recurrent erythema multiforme
|
HSV
|
|
|
Drug used to prevent cyclophosphamide induced hemorhaddic cystitis
|
Mesna
|
|
|
Antidote for viagra toxicity
|
Methylene blue
|
|
|
Normal cup/disc ratio on fundoscopy
|
<0.5
|
|
|
Treatment of high altitude cerebral edema
|
Dexmethasone
|
|
|
Treatment of mild alzheimer dementia
|
Donepezil
|
|
|
Tx for pseudo tumor cerebri
|
Acetazolamide
|
|
|
Severe orthostatic hypotension with ataxia and Parkinsonism
|
Shy-Drager syndrome/multiple system atrophy
|
|
|
Recurrent episodes of myelitis, optic neuritis without brain lesions on MRI
|
NMO, Devic's disease
|
|
|
Acute onset unilateral headache with C/F of Horner syndrome
|
Carotid artery dissection
|
|
|
Drug beginning with "P" that is used for treatment of essential tremor
|
Propanolol or primidone
|
|
|
Drug beginning with "P" that is treatment of restless leg syndrome
|
Pramipexole
|
|
|
Antiplatelet drug with faster and better inhibition that clopidogrel used in ACS
|
Prasugrel
|
|
|
Drug beginning with "P" which causes total body alopecia and bradyarrhthmia
|
Paclitaxel
|
|
|
#1 cause of adrenal insufficiency worldwide
|
Tuberculosis
|
|
|
The association between thyroid disease and adrenal insufficiency +/- type 1 diabetes is described by this syndrome
|
Schmidt's syndrome or polyglandular 2
|
|
|
Syndrome occuring secondary to bilateral adrenalectomy often presenting with hyper pigmentation
|
Nelsons syndrome
|
|
|
Polyglandular syndrome type 1 is associated with mucocutaneous candidiasis, adrenal failure and this
|
Hypoparathyroidism
|
|
|
Malfunction of medial temporal love and amygdala resulting in hypersexuality and hyperorality
|
Kluver-bucy syndrome
|
|
|
Treatment of HIV is started for a CD4 count below this
|
350
|
|
|
Esophagitis in HIV with multnucleated giant cells on histology
|
HSV
|
|
|
Integrase inhibitor
|
Raltegravir
|
|
|
Steroids added to PCP treatment in these two situations
|
A-a gradient >35 p02 < 70
|
|
|
CCR5 inhibitor
|
Maraviroc..selzentry
|
|
|
Drug beginning with "I" that can cause crystalluria
|
Indinavir
|
|
|
Drug beginning with "I" that is used to treat hepatitis "C"
|
Pegylated Interfeuron alpha 2a
|
|
|
Treatment for pulmonary hypertension
|
Iloprost
|
|
|
Drug used to treat multiple sclerosis
|
Interfeuron beta
|
|
|
This drug is derived from the saliva of the gila monster
|
Exenatide
|
|
|
Blood pressure and LDL goal in diabetes mellitus
|
Glutamic acid decarboxylase
|
|
|
This DPP-IV inhibitor has been associated with URTI symptoms as a side effect
|
Sitagliptin
|
|
|
This 2009 trial demonstrated that intensive blood glucose control increased mortality in ICU patients
|
Nice-sugar
|
|
|
This form in influenza vaccine is live attenuated
|
Intranasal
|
|
|
Age range for HPV vaccine
|
9-26
|
|
|
Usual age at which pneumococcal vaccine is given in a healthy individual
|
65 years
|
|
|
Age at which herpes zoster vaccine is given in a healthy individual
|
60 years
|
|
|
Anyone born before this year is considered to be immune to mumps
|
1957
|
