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9 Cards in this Set

  • Front
  • Back
What two changes occur in the vascular supply to the disk with aging?
Vessels begin disappearing after the age of 1- years
Endplates ossify
What is the source of nutrients to the disk?
Diffusion through endplates
What two external factors decrease endplate permeability?
Smoking
Vibration
What factors increase permeability?
Exercise
How does aging affect the disk's collagen content?
Decreased collagen content
How does aging affect the disk's fibril diameter?
Increased fibril diameter and variability
How does aging affect the disk's noncollagenous protein?
Increased noncollagenous protein
How does aging affect the disk's pH?
Decreased pH
Magnetic resonance imaging (MRI): what are the rates of false-positive (asymptomatic) findings for patients <40 yrs old, >40 yrs old, and >60 yrs old?
<40 yrs old: 25%
>40 yrs old: 60%
>60 yrs old: 90%