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10 Cards in this Set

  • Front
  • Back
What are the two major drawbacks to plate-and-screw fixation of allograft to native bone for reconstruction after tumor
surgery?
High allograft fracture rate
10% deep infection rate
What anatomic location is particularly prone to complications with this method?
Proximal tibia
What is the relative advantage of this method of Hxation?
Relatively high rates of union
What three tumors are the classic low-grade malignant tumors of bone?
Adamantinoma
Parosteal osteosarcoma
Chordoma
Because they are low grade how are these tumors generally treated?
Wide resection only
Chemotherapy is generally helpful for the what four tumors?
Acronym: MOLE
Metastases
Osteosarcoma
Lymphoma
Ewing sarcoma
Radiation therapy is generally helpful for what five tumors?
Acronym: ELMMS
Ewing sarcoma
Lymphoma
Multiple myeloma
Metastases
Soft tissue sarcoma
By what mechanism is radiation therapy thought to act?
Oxygenates intracellular water
Damages DNA of tumor cells
What are the two potential therapeutic uses of strontium in patients with neoplasms?
Control pain from bony
metastases
Localizes selectively within bone and irradiates bony metastases from within
What complication is classically associated with doxorubicin?
Cardiac toxicity