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58 Cards in this Set

  • Front
  • Back

In genetics research, thestudy of first-degree relatives reared indifferent families and environments. Ifthey share common characteristics, suchas a disorder, this finding suggests that those characteristics have a genetic component.

adoption studies

Approach to researchemploying subjects who are similar to clinicalclients,allowingreplicationof a clinicalproblem under controlled conditions

analogue model

Research strategies forcomparing genetic markers in groups ofpeople with and without a particular disorder.

association studies

Measured rate of a behaviour before introduction of an intervention that allows comparison and assessment of the effects ofthe intervention.

baseline

Research procedure inwhich a single person or small group isstudied in detail. The method does notallow conclusions about cause-and-effectrelationships, and findings can be generalizedonlywithgreatcaution.

case study method

Degree to which researchfindings have useful and meaningful applicationstorealproblems.

clinical significance

Participants in each age group of across-sectional research study.

cohort

Observation that people of differentagegroupsalsodifferin their valuesandexperiences.

cohort effect

Outcomeresearch that contrasts two or more treatmentmethodstodeterminewhichismosteffective.

comparative treatment research

Any factor occurring in a research study that makes the results uninterpretablebecause its effects cannot be separated fromthose of the variables being studied

confound

Group of individuals in aresearch study who are similar to the experimentalsubjectsin everywaybutarenotexposedtothetreatmentreceivedbytheexperimentalgroup;theirpresenceallowsforacomparisonofthedifferentialeffectsofthetreatment.

control group

Degree to which two variables areassociated.

correlation

Computed statisticreflecting the strength and direction of anyassociation between two variables. It canrange from +1.00 through zero (indicating no association) to –1.00, with the absolute value indicating the strength, and the signreflecting the direction.

correlation coefficient

Limit to the generalizabilityoflongitudinalresearchbecausethegroupunderstudymaydifferfromothersin cultureandexperience.

cross-generational effect

Methodology toexamine a characteristic by comparing differentindividualsofdifferentages.Contrastwithlongitudinaldesign.

cross-sectional design

In an experimentalresearch study, the phenomenon that is measuredandexpectedtobeinfluenced

dependent variable

The possibility that, when twovariables, A and B, are correlated, variable Acauses variable B, or that B causes A.

directionality

Procedure in outcomestudies that prevents bias by ensuring thatneither the subjects nor the providers of theexperimental treatment know who isreceiving treatment and who is receivingplacebo.

double-blind control

How big the difference between two group is

effect size

Thegenetic mechanisms that ultimately contributeto the underlying problems causing thesymptomsand difficultiesexperiencedbypeoplewith psychological disorders

endophenotypes

Psychopathology researchmethod examining the prevalence, distribution,andconsequences of disorders inpopulations.

epidemiology

Research method that can establishcausationbymanipulating the variablesinquestion and controlling for other alternative explanations of any observedeffects.

experiment

Extent to which researchstudy findings generalize, or apply, to peopleand settings not involved in the study

external validity

Genetic studies that examinepatterns of traits and behaviours among relatives.

family studies

Extent to which researchresults apply to a range of individuals notincluded in the study.

generalizability

Studies that seek tomatch the inheritance pattern of a disorderto that of a genetic marker; this helpsresearchers establish the location of thegene responsible for the disorder.

genetic linkage analysis

Inherited characteristic forwhich the chromosomal location of theresponsible gene is known.

genetic marker

Specific genetic makeup of anindividual

genotype

Ongoing scientific attempt to develop a comprehensive map ofall human genes.

human genome project

Educated guess or statement to betested by research.

hypothesis

Number of new cases of a disorderappearing during a specific time period

incidence

Phenomenon that ismanipulated by the experimenter in aresearch study and expected to influence thedependent variable.

independent variable

Ethical requirementwhereby research subjects agree to participateina research study only after they receive full disclosure about the nature of the study andtheirown role in it.

informed consent

Extent to which the resultsof a research study can be attributed to theindependent variable after confoundingalternative explanations have been ruledout.

internal validity

Degree of behaviour change withdifferent interventions (e.g., high, low).

level

Systematic study ofchanges in the same individual or groupexamined over time

longitudinal design

Single-case experimentaldesign in which measures are taken on two ormore behaviours, or on a single behaviour intwo or more situations. A particular interventionisintroducedforeachatdifferenttimes.Ifbehaviourchangeiscoincident witheachintroduction,thisisstrongevidencetheinterventioncausedthechange

multiple baseline

Association betweentwo variables in which one increases as theother decreases.

negative correlation

The tendency to see all participants as one homogeneousgroup

patient uniformity myth

Observable characteristics orbehaviours of an individual.

phenotype

In an outcomeexperiment, a control group that does notreceive the experimental manipulation butis given a similar procedure with an identicalexpectationofchange,allowingtheresearchertoassessanyplaceboeffect.

placebo control group

Behaviour change resultingfrom the person’s expectation of changerather than from the experimental manipulationitself.

placebo effect

Association between twovariables in which one increases as the otherincreases.

positive correlation

Number of people displaying a disorderin thetotalpopulationatanygiventime

prevalence

In genetics research, the individualdisplaying the trait or characteristic beingstudied. Also known as index case.

proband

Method for placing individualsinto research groups that assures each one ofan equal chance of being assigned to anygroup, to eliminate any systematic differencesacrossgroups

randomization

repeated measurement

Plan of experimentation usedto test a hypothesis

research design

Literally “the view back,” data collected by examining records or recollections of the past. It is limited bythe accuracy, validity, and thoroughness ofthe sources.

retrospective information

Combination of the cross-sectionalandlongitudinalresearchmethodsinvolvingrepeatedstudyofdifferentcohortsovertime.

sequential design

Researchtactic in which an independent variable ismanipulated for a single individual, allowingcause-and-effect conclusions, but with limited generalizability.

single-case experimental design

Probability thatobtaining the observed research findingsmerely by chance is small

statistical significance

Ability of a hypothesis, for example,to be subjected to scientific scrutiny and to be accepted or rejected, a necessary conditionforthehypothesistobeuseful.

testability

Studies of the effectiveness of clinical interventions, including the comparison of competingtreatments.

treatment outcome research

The direction of change of a behaviour orbehaviours (e.g., increasing, decreasing).

trend

In genetics research, the comparisonoftwinswithunrelatedorless closely related individuals. If twins, particularlymonozygotictwinswhoshareidenticalgenotypes,sharecommoncharacteristicssuchasadisorder,eveniftheywererearedindifferentenvironments,thisisstrongevidenceofgeneticinvolvementin thosecharacteristics.

twin studies

Degree of change in a phenomenonovertime.

variability

Removing a treatment tonote whether it has been effective. Insingle-case experimental designs, abehaviour is measured (baseline), an independentvariable is introduced (intervention), and then the intervention iswithdrawn. Because the behaviourcontinues to be measured throughout(repeated measurement), any effects of theintervention can be noted. Also calledreversal design.

withdrawal design