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99 Cards in this Set
- Front
- Back
The fundamental experiences of what contribute, either singly or together, to all the mood disorders?
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Depression and Mania
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What is the most commonly diagnosed and most severe depression?
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Major Depressive Episode
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Major Depressive Episode
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An extremely depressed mood state that lasts at least 2 weeks and includes cognitive symptoms and disturbed physical functions to the point that even the slightest activity or movement requires an overwhelming effort. Accompanied by a general loss of interest in things and an inability to experience any pleasure from life.
Cognitive Symptoms- feelings of worthlessness, indecisiveness, etc. Disturbed Physical Functions- altered sleeping patterns, changes in appetite and weight, loss of energy |
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What are the most central indicators of a full major depressive episode?
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Physical Changes (somatic or vegetative symptoms)
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Anhedonia
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loss of energy and inability to engage in pleasurable activities
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Mania
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Individuals in mania find extreme pleasure in every activity. They become hyperactive, require little sleep, and may develop grandiose plans with the belief that they can accomplish anything they desire.
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Flight of Ideas
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When in mania, speech is typically rapid and may become incoherent because the individual is attempting to express so many exciting ideas at once
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Hypomanic Episode
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A less severe version of a manic episode that does not cause marked impairment in social or occupational functioning and need only last 4 days rather than a full week.
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Hypo-
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Below
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Unipolar Mood Disorder
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When mood remains at one "pole" of the usual depression-mania continuum
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Why is Unipolar Mania rare?
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Because most people with a unipolar mood disorder go on to develop depression eventually
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Bipolar Mood Disorder
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When one alternates between depression and mania
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Dysphoric Manic Episode or Mixed Manic Episode
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When one experiences manic symptoms, but feels depressed or anxious at the same time. The patient usually experiences the symptoms of mania as being out of control or dangerous and becomes anxious or depressed about this uncontrollability.
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Major Depressive Disorder, Single Episode
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When there is an absence of manic or hypomanic episodes before or during the disorder. Relatively Rare.
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Major Depressive Disorder, Recurrent
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When two or more major depressive episodes occurred and were separated by at least 2 months during which the individual was not depressed.
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Dysthymic Disorder
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Mood disorder involving persistently depressed mood, with low self-esteem, withdrawal, pessimism, or despair, present for at least 2 years, with no absence of symptoms for more than 2 months. Symptoms are less severe and less in quantity from a major depressive episode, but last longer.
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Double Depression
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Sever mood disorder typified by major depressive episodes superimposed over a background of dysthymic disorder.
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Typical Duration of the First Episode of Depression
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4-9 months if untreated
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Onset of Dysthymic Disorder before 21 Years of Age is associated with what characteristics?
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1. Lasts Longer
2. Poor response to treatment 3. Stronger likelihood of the disorder running in the family of the affected individual 4. More likely to have concurrent personality disorder |
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Median Duration of Dysthymic Disorder
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5 years in adults / 4 years in children
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When is a depressive episode after the death of a loved one considered a disorder?
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When severe symptoms appear, such as psychotic features or suicidal ideation, or the less alarming symptoms last longer than 6 months.
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Pathological or Impacted Grief Reaction
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Extreme reaction to the death of a loved on that involves psychotic features, suicidal ideation, or severe loss of weight or energy that persists more than 2 months. History of past depressive episodes can help predict this.
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What is one therapeutic approach to help grieving individuals?
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Reexperiencing the trauma under close supervision. The person is encouraged to talk about the loved one, the death, and the meaning of the loss while experiencing all associated emotions, until that person can come to terms with reality. This would include incorporating positive emotions connected with the loss and arriving at the position that it is possible to cope with the pain and life will go on.
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What is the key identifying feature of bipolar disorders?
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The tendency of manic episodes to alternate with major depressive episodes is an unending roller-coaster ride from the peaks of elation to the depths of despair.
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Hallucinations
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Psychotic symptom or perceptual disturbance in which something is seen, heard, or otherwise sensed although it is not actually present
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Delusions
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Psychotic Symtom involving disorder of thought content and presence of strong beliefs that are misrepresentations of reality.
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Catalepsy
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Motor movement disturbance seen in people with some psychoses and mood disorders in which body postures can be "sculpted" to remain fixed for long periods.
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Seasonal Affect Disorder (SAD)
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Mood disorder involving a cycling of episodes corresponding the the seasons of the year, typically with depression occurring during the winter.
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Bipolar II Disorder
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Alternation of major depressive episodes with hypomanic episodes (not full manic episodes)
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Bipolar I Disorder
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Alternation of major depressive episodes with full manic episodes
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Cyclothymic Disorder
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Chronic (at least 2 years) mood disorder characterized by alternating mood elevation and depression levels that are not as severe as manic or major depressive episodes
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When do patients often deny they have a problem?
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During manic or hypomanic phases (they are so wrapped up in their enthusiasm and expansiveness that their behavior seems reasonable to them, and often stop taking their medication during periods of distress or discouragement in an attempt to bring on a manic stage)
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Individuals with cyclothymic disorder tend to be in one mood state or the other for how long, with few periods of neutral mood?
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Years
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Euthymic
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Neutral Mood
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How long must the pattern last for a child or adolescent to meet the criteria for cyclothymic disorder?
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1 year, as opposed to 2 in adults
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What is the average age of onset for bipolar I disorder?
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15-18
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What is the average age of onset for bipolar II disorder
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19-22
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What are the differences between the onset of Bipolar Disorders and Major Depressive Disorders?
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Bipolar Disorder has a younger average age of onset and begins more acutely (suddenly).
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Rates of completed suicide are how much higher in patients with bipolar disorder than recurrent major depression?
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4 times
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How long does Cyclothymia last?
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Usually chronic and lifelong
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Average age of onset for Cyclothymia?
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12-14
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Subtypes of Cyclothymia?
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Based on predominance of mild depressive symptoms, hypomanic symptoms, or equal distribution of both.
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What percent of the population worldwide experience major depressive disorder over a lifetime? In the past year?
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16% over a lifetime
6% in the past year |
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Likelihood of mood disorders in women and men?
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Women are twice as likely to have mood disorders as men. (Equal until adolescence and after age 65)
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Likelihood of bipolar disorder in women and men?
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Equal
Women are more likely to experience rapid cycling, anxiousness, and depressive phase. |
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Likelihood of major depressive disorder and dysthymia in blacks and whites?
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The prevalence of major depressive disorder and dysthymia is significantly lower among blacks than among whites
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Depressive disorders in kids and adults?
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Depressive disorders occur less often in prepubertal children than in adults but rise dramatically in adolescence
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Depressive disorders in population v individuals older than 65?
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The overall prevalence of major depressive disorder for individuals older than 65 is about half that of the general population.
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Childhood depression and mania is often associated with and misdiagnosed as what?
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ADHD
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Proband
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first-degree relatives
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Are mood disorders heritable?
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This seems to be the case because identical twins are 2-3 times more likely to present a mood disorder than a fraternal twin if the first twin has a mood disorder
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Environmental events influence on depression in men and women?
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Environmental events play a larger role in causing depression in men than in women
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Median lifetime number of major depressive episodes
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4-7
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Median length of a major depressive episode?
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4-5 months
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Average Age of onset for Major Depressive Disorder (MDD)
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30
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Average Age of onset for Dysthymic Disorder
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Early 20's
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Dysthymic Disorder Prevalence
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3.5% lifetime and past year
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Who is more likely to commit suicide...those with DD or MDD?
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Dysthymic Disorder
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Strongest Risk Factors for MDD in the Elderly
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1) loss of a loved one
2) loss of independence due to illness 3) Caregiving burden for ill spouse |
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Genetic Contributions to depression in men v women...
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There is more of a genetic contribution in women to depression
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Biological Causes of Depressive Disorders
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Low Levels of Serotonin (emotion regulator) in relation to norephinephrine and dopamine
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Permissive Hypothesis
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When serotonin is low, it allows other NT's to range more widely and be dis-regulated, causing unstable mood.
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The Endocrine System on Depression
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Overproduction of cortisol prohibits neurogenesis. This suppression in the hippocampus may be one cause of depression
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Psychological Causes of Depression
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Stressful life events, learned helplessness, negative cognitive styles
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Learned Helplessness
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starts as anxiety, then depression comes after a marked feeling of hopelessness in ability to cope with the situation and results in behaving helplessly
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Negative Cognitive Styles
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Cognitive Errors:
Arbitrary inference Overgeneralization Depressive Cognitive Triangle Negative Schema |
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Attentional Biases in Depression
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Depressed people tend to remember more negative events and less positive events
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Social Risk Factors for Depressive Disorders
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Marital Dissatisfaction (particularly for men), smothering/overprotective parenting, women place a greater emphasis on interpersonal relationships so disruptions are more problematic
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Cultural Risk Factors for Depressive Disorders
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Women face more adversity and feel uncontrollability due to dependence and passivity of cultural expectations
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The importance of social support to depression
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Depression can lead to isolation, so more meaningful and greater number of social relationships and contacts is related to living longer and less depression
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Medicinal Treatment of Depressive Disorders
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Antidepressants:
SSRI SNRI Tricyclics- bad side effects MAO's: for depression with atypical features such as adverse interactions with foods and medicines |
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Goal of Medicine in Depression
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to prevent next episode, so treatment usually lasts for 6-12 months after episode
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ECT
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used with those not responding to meds
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Psychological Treatment for Depressive Disorders
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CBT: addresses cognitive styles
IPT: addresses resolution of interpersonal problems and stressors |
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Preventative Approaches for Depression
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Universal programming, selected interventions, indicated interventions
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Medication vs. Therapy
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Combined treatment may be best, but there are better long term effects and relapse prevention with cognitive therapy
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Gender Differences in Suicide
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Males are 4 times more likely to commit suicide, but women attempt more.
Suicide rates for young men in the U.S. are highest in the world. In China more women commit suicide than men, especially in rural areas |
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Risk Factors of Suicide
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Mood, substance use or impulse control disorders (account for 80% of suicides)
Low levels of serotonin Family History of Suicide Family Violence Firearms in home Stressful events experienced as shameful or humiliating Stress and disruption of natural disasters Exposure to suicidal behavior of others |
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Bully Victims and Suicide
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Bully Victims are between 2-9 times more likely to consider suicide than non victims
Half of suicides among young people are related to bullying |
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Mood Disorder Specifiers
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Seasonal Pattern
Postpartum Anxious Distress Mixed Features Melancholic Features Atypical Features Mood-Congruent Psychotic Features Mood-incongruent Psychotic Features Catatonia |
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Psychosis
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Hallucinations and delusions
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Rapid Cycling Specifier
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4 or more episodes of manic or depressive symptoms in a 12 month period
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Advancements of BD
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1/3 with Cyclothymic Disorder will develop BD
10-25% of people with BDII will Develop BD 1 |
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BD Prevalence
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BD 1% lifetime; .08% in the past year
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Bipolar Disorder has a strong concurrence with what?
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Substance abuse disorder
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Neurotransmitters in BD
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low serotonin, dis-regulation of dopamine
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Psychological Causes/ Risk factors for BD
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stress, opportunities to strive for a goal, loss of sleep
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Medicinal Treatment of Bipolar Disorder
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Lithium (most common, but severe side-effects)
SSRI's: can trigger manic episodes Anticonvulsants: good for rapid cycling (less effective at preventing suicide) |
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SSRI
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Selective Serotonin Reuptake Inhibitor: increase serotonin by decreasing reuptake
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Psychological Treatment of BD
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Aims to manage interpersonal and practical problems and compliance with drug treatment
CBT- especially useful when rapid cycling is present Psychosocial Treatments |
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Changes to Depressive Disorders in DSMV
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Disruptive Mood Dysregulation Disorder: children up to 18 years of age who exhibit persistent irritability and extreme episodes of behavior dyscontrol (attempt to reduce overdiagnosis of Bipolar Disorder in Children)
Premenstrual Dysphoric Disorder: depressive disorder that begins sometime following ovulation and remits within a few days of menses and has a marked impact of Functioning Persistent Depressive Disorder (Dysthymia) Bipolar Disorder moved to separate chapter from depressive disorders |
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Why was BD moved to separate chapter from DD?
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genetic contribution seems to be higher than in DD, age of onset is earlier, more insidious onset, different pharmacological treatments
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Cortisol
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Released in Response to Stress
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Arbitrary inference
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Emphasize Negatives
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Depressive Cognitive Triangle:
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Negative cognitions about themselves, their immediate world, and their future
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Negative Schema
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Self Blame, Self Evaluation
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Internal, Stable, & Global Learned helplessness
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internal- attributes negative events to personal failings
stable- even after event passes thinks additional bad things will always be their fault global- attributions extend across a range of issues |
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SNRI
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Serotonin-norepinephrine reuptake inhibitor- increase seratonin and norepinephrine
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Catatonia
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neurogenic motor immobility and behavioral abnormality
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