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27 Cards in this Set

  • Front
  • Back
BRAND NAME:

Adalimumab
Humira
INDICATIONS:

Adalimumab
-Ankylosing spondylitis
-Crohn's Disease
-Plaque psoriasis
-Psoriatic arthritis
-RA
-Ulcerative colitis
THERAPEUTIC CLASS:

Adalimumab
TNF-alpha inhibitor
SIDE EFFECTS:

Adalimumab
-Headache
-Rash
-Positive ANA titer
-Antibody development
-Serious infection
-Injection site reactions
-Increased CPK
-URI, sinusitis
BLACK BOX WARNING:

Adalimumab
Patients treated with adalimumab are AT INCREASED RISK FOR INFECTIONS, some progressing to serious infections leading to hospitalization or death. These infections have included bacterial sepsis, tuberculosis, invasive fungal, and other opportunistic infections including Legionella and Listeria.

Evaluate for latent tuberculosis and treat if necessary prior to initiation of therapy.

LYMPHOMA and other MALIGNANCIES, some fatal, have been reported in children and adolescent patients treated with tumor necrosis factor (TNF) blockers, of which adalimumab is a member Postmarketing cases of hepatosplenic T-cell lymphoma (HSTCL), usually fatal, have been reported in patients treated with TNF blockers including adalimumab, primarily in adolescent and young adult males with Crohn's disease and ulcerative colitis. Most of these cases of HSTCL occurred in patients receiving concomitant treatment with azathioprine or 6-mercaptopurine [2].
DRUG DRUG INTERACTIONS:

Adalimumab
-Live vaccines (C/I)
-Tacrolimus (decreased tacrolimus exposure)
-Cyclosporine (decreased cyclosporine exposure)
-Abatacept, anakinra (increased risk of infections)
BRAND NAME:

Atovaquone
Mepron
INDICATIONS:

Atovaquone
-Pneumocystis pneumonia (PCP) - prevention and treatment (mild-to-moderate)
THERAPEUTIC CLASS:

Atovaquone
-Antiprotozoal
-Ubiquinone
SIDE EFFECTS:

Atovaquone
-Rash
-Abdominal pain
-N/V/D
-Asthenia
-Headache
-Insomnia
-Cough
-Dyspnea
-Rhinitis
-Fever
-Infectious disease
COUNSELING POINTS:

Atovaquone
Take with meals (as reduced absorption may result if taken on an empty stomach).
DOSAGE FORM:

Atovaquone
Oral suspension: 750 mg/5 mL
DRUG DRUG INTERACTIONS:

Atovaquone
Rifampin (decreased atovaquone plasma concentrations)
BRAND NAME:

Diltiazem
Cardizem
Cardizem CD
INDICATIONS:

Diltiazem
-Atrial arrhythmia
-HTN
-Paroxysmal supraventricular tachycardia
-Chronic stable angina
THERAPEUTIC CLASS:

Diltiazem
Calcium channel blocker
SIDE EFFECTS:

Diltiazem
-Peripheral edema
-Fatigue
-Dizziness
-HA
DRUG DRUG INTERACTIONS:

Diltiazem
-Atazanavir - prolonged PR interval
-Clozapine
-Colchicine (increased colchicine concentrations)
-Simvastatin (increased simvastatin concentrations; increased risk of myopathy, incl rhabdomyolysis)
-Clarithromycin (increased diltiazem exposure)
-Clopidogrel (decreased antiplatelet effect and increased risk of thrombotic events)
CONTRAINDICATIONS:

Diltiazem
-Acute MI w/ pulmonary congestion on xray
-A Fib or flutter associated w/ an accessory bypass tract (Wolff-Parkinson-White or short PR syndromes) - IV only
-Cardiogenic shock (IV only)
-2nd or 3rd degree AV heart block w/out a functioning pacemaker
-Symptomatic hypotension (systolic < 90 mmHg)
-Newborns (some injections contain benzyl alcohol)
-Sick sinus syndrome w/out a functioning ventricular pacemaker
-Ventricular tachycardia (IV only)
BRAND NAME:

Famotidine
Pepcid
INDICATIONS:

Famotidine
-Duodenal ulcer disease
-GERD
-Gastric hypersecretion
-Gastric ulcer
-Indigestion
THERAPEUTIC CLASS:

Famotidine
H2 blocker
DRUG DRUG INTERACTIONS:

Famotidine
-HIV drugs - atazanavir, rilpivirine (decreased concentration of HIV drugs)
BRAND NAME:

Hydrocodone/APAP
Vicodin
Lortab
Norco
INDICATIONS:

Hydrocodone/APAP
Moderate to moderate-severe pain
THERAPEUTIC CLASS:

Hydrocodone/APAP
Opioid/APAP combo
SIDE EFFECTS:

Hydrocodone/APAP
-Constipation
-Dizziness
-N/V
-Sedation
-Urinary retention