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35 Cards in this Set

  • Front
  • Back
Percent of female cancers that are breast cancers?
26% (highest)
% of breast cancers that kill?
15% (2nd highest)
Lifetime probability of developing cancer (in women)?
1 in 3
Lifetime probability of developing breast cancer?
1 in 7 (or 8)
how many lobules in a normal mature breast?
15-20 that drain via the ducts to the nipple
2 types of breast cancer?
Ductal
Lobular
Which is more prominent type?
Ductal
Uniqueness of Lobular breast cancer?
Multicentric/Bilateral
What is the most common tissue/cell source of cancer?
Epithelial

colon, lung, prostate, ductal boob
Triad of Breast Cancer screening?
SBE
CBE
MMG
American Cancer Society says to start MMG's...
at 40 as long as they're healthy
ACS and CBE's?
Every 3yrs for 20's and yearly for 40 and up
SBE ACS rec?
starting in 20s
What should high risk women get yearly?
MRI
what is high risk?
greater than 20% lifetime risk
6 Elements to History Taking?
Initiating the Session
Gathering Info
Giving Info
Understand Patient's Perspective
End the Encounter
Nonverbal Communication Skills
Breast Cancer Risk Factors?
Age
Family History
Prior personal h/o breast cancer
Increased Estrogen Exposure
Diet and Lifestyle
Radiation Exposure before 40
Prior Benign or premalignant breast changes
Conditions leading to increased estrogen exposure?
Early Menarche/Late Menopause
HRT/OCP
Nulliparity
1st pregnancy after 30
Diet and Lifestyle stuff increasing risk of breast cancer?
Fat
Excessive Alcohol
Parts of Family History leading to inc risk of boob cancer?
Maternal AND paternal
1st degree relative
Age of onset
Bilateral Disease
Multiple primary cancers (boob/ovarian)
Ethnicity
Genes and inc Breast Cancer risk?
BRCA 1 and 2
Normal lifetime risk of breast cancer in general population vs w/ positive FH vs positive BRCA1/2 mutation?
11-12%
20-25%
65-85%
Keys to Inspection?
BREAST

Breast mass
Retraction
Edema (orange peel)
Asymmetry
Scaly Nipple
Tenderness
MMG Classification system?
ACR BIRADS
Categories for ACR BIRADS?
0=need additional imaging evaluation
1=negative
2=benign finding
3=probably benign, but short interval follow-up
4=Suspicious abnormality, consider bx
5=highly suggestive of malignancy, take action
on ultrasound, what appears fluid filled (black) w/ smooth walls?
Classic Breast Cyst
How can cancer look on U/S?
Taller than wide w/ irregular borders
besides high risk women, who else gets an MRI?
dense breasts
Efficacy of Fine Needle Aspiration?
Easy and Accurate
False negative due to sampling error
RARE False positives
What if the FNA is non-diagnostic?
Repeat or do another type of bx...
Other types of Bx?
Core Bx
Needle-Localized Breast Bx
most common type of benign breast tumor?
Fibroadenoma
Rates of false positives and false negatives in Axilla exam?
1/3 false pos
1/3 false neg
How do we test LN's?
Sentinel Lymph Node Bx
How does SLN Bx work?
ID principal node of spread
Get rid of it and others found

Spares some...