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35 Cards in this Set
- Front
- Back
Percent of female cancers that are breast cancers?
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26% (highest)
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% of breast cancers that kill?
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15% (2nd highest)
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Lifetime probability of developing cancer (in women)?
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1 in 3
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Lifetime probability of developing breast cancer?
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1 in 7 (or 8)
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how many lobules in a normal mature breast?
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15-20 that drain via the ducts to the nipple
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2 types of breast cancer?
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Ductal
Lobular |
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Which is more prominent type?
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Ductal
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Uniqueness of Lobular breast cancer?
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Multicentric/Bilateral
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What is the most common tissue/cell source of cancer?
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Epithelial
colon, lung, prostate, ductal boob |
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Triad of Breast Cancer screening?
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SBE
CBE MMG |
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American Cancer Society says to start MMG's...
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at 40 as long as they're healthy
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ACS and CBE's?
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Every 3yrs for 20's and yearly for 40 and up
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SBE ACS rec?
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starting in 20s
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What should high risk women get yearly?
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MRI
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what is high risk?
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greater than 20% lifetime risk
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6 Elements to History Taking?
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Initiating the Session
Gathering Info Giving Info Understand Patient's Perspective End the Encounter Nonverbal Communication Skills |
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Breast Cancer Risk Factors?
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Age
Family History Prior personal h/o breast cancer Increased Estrogen Exposure Diet and Lifestyle Radiation Exposure before 40 Prior Benign or premalignant breast changes |
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Conditions leading to increased estrogen exposure?
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Early Menarche/Late Menopause
HRT/OCP Nulliparity 1st pregnancy after 30 |
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Diet and Lifestyle stuff increasing risk of breast cancer?
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Fat
Excessive Alcohol |
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Parts of Family History leading to inc risk of boob cancer?
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Maternal AND paternal
1st degree relative Age of onset Bilateral Disease Multiple primary cancers (boob/ovarian) Ethnicity |
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Genes and inc Breast Cancer risk?
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BRCA 1 and 2
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Normal lifetime risk of breast cancer in general population vs w/ positive FH vs positive BRCA1/2 mutation?
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11-12%
20-25% 65-85% |
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Keys to Inspection?
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BREAST
Breast mass Retraction Edema (orange peel) Asymmetry Scaly Nipple Tenderness |
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MMG Classification system?
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ACR BIRADS
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Categories for ACR BIRADS?
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0=need additional imaging evaluation
1=negative 2=benign finding 3=probably benign, but short interval follow-up 4=Suspicious abnormality, consider bx 5=highly suggestive of malignancy, take action |
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on ultrasound, what appears fluid filled (black) w/ smooth walls?
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Classic Breast Cyst
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How can cancer look on U/S?
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Taller than wide w/ irregular borders
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besides high risk women, who else gets an MRI?
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dense breasts
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Efficacy of Fine Needle Aspiration?
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Easy and Accurate
False negative due to sampling error RARE False positives |
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What if the FNA is non-diagnostic?
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Repeat or do another type of bx...
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Other types of Bx?
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Core Bx
Needle-Localized Breast Bx |
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most common type of benign breast tumor?
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Fibroadenoma
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Rates of false positives and false negatives in Axilla exam?
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1/3 false pos
1/3 false neg |
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How do we test LN's?
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Sentinel Lymph Node Bx
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How does SLN Bx work?
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ID principal node of spread
Get rid of it and others found Spares some... |