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20 Cards in this Set
- Front
- Back
DDx of Baker's cyst
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DVT (always consider)
popliteral artery aneurysm lymphadenopathy tumor |
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If Osgood-Schlatter does not remit with rest, what is the next step?
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steroids
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What are the calcium phosphate and alk phos levels in osteoporosis?
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all normal!
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What are the calcium phosphate and alk phos levels in osteomalacia?
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low calcium
low phosphorous (PTH activated) high alk phos (leeching) |
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What are the calcium phosphate and alk phos levels in Paget's?
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calcium and phosphorous are NORMAL, but alk phos is very high
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What are the calcium phosphate and alk phos levels in renal osteodystrophy?
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calcium is low (why?)
phosphorous is HIGH (can't excrete) alk phos is high |
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What are the calcium phosphate and alk phos levels in hyperparathryroidism?
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calcium is high (leeching)
phosphorous is low (PTH activated, excreting P) alk phos is high |
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Which metabolic bone disorders have normal calcium and phosphorous?
Which have normal alk phos? |
osteoporosis
Paget's (only alk phos elevated) osteoporosis (all labs normal) |
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Paget's affects the [axial, appendicular] skeleton more
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axial
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In addition to multiple myeloma, what bone dz has lytic lesions on skull xray?
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Paget's
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What are diagnostic/imaging markers for Paget's
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1. Bone scan > xray
2. urine hydroxyproline 3. 24 hour urine N-telopeptide |
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Paget's has potential for malignant transformation, especially in ? and ?
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humerus and femur
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Treatment for Paget's
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bisphosphonates
calcitonin analogs |
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What end-organ problem (besides bon) can Paget's cause?
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high output cardiac failure
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Palpable purpura:
how are they distinguished clinically what are they pathognomonic for |
they do not blanch, b/c they are not vascular
pathogn. of vasculitis |
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What are the 3 hypersensitivity vasculitides?
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cryoglobulinemia
Henoch-Schonlein purpura serum sickness |
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What are the two main clinical signs of hypersensitivity vasculitis?
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1. palpable purpura
2. neutrophils in perivascular space on biopsy ("leukocytoclastic") -- but this is also seen in endocarditis, EBV, HIV, hepatitis, ulcerative colitis, PBC. |
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What happens to patients with cryoglobulinemia when they get cold?
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they get palpable purpura
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Monoclonal cryoglobulinemia is associated with what disorders?
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Multiple myeloma
Waldenstrom's lymphoma leukemia |
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Symptoms of monoclonal cryoglobulinemia (MM, Waldenstrom)?
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hyperviscosity symptoms:
headaches blurry vision EPISTAXIS Raynaud's ISCHEMIC ULCERS, skin necrosis |