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21 Cards in this Set

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  • Back
Chest pain suggestive of MI: must rule out?
aortic dissection (CXR, mediastinal widening; US)
pneumothorax (CXR)
Boerhaave's (ruptured esophagus)
Chest pain suggestive of MI: immediate medications and support
MONA: morphine, O2, nitro, aspirin to chew
also beta blockers
establish IV and monitor
consider thrombolytics if STEMI
What is the difference in cause of STEMI and NSTEMI?
STEMI: occlusion, transmural infarct
NSTEMI: subendocardial infarct
UA: ischemia
Chest pain suggestive of MI: What diagnostic tests should be ordered?
ECG within 10 minutes
cardiac enzymes (troponin, myoglobin, CKMB)
CBC, Chem 7
sometimes type and cross, CXR (to rule out other causes and ID pulmonary edema)
Chest pain suggestive of MI: if the ECG shows STEMI that is less than 12 hours old, what is next step?
Either PCI (angioplasty / stenting) or thrombolysis. PCI is preferred.
What does the TIMI score measure?
Risk of MI, death or revascularization within two weeks by points.
2 points, 8%
3 points, 13%
4 points, 20%
6 points, 21%
What is the mnemonic for the risk factors in the TIMI 2-week risk score?
ARKANASAS
age > 55
risk factors 3+
known CAD
aspirin in last 7 days
ST elevation or depression
angina x 2 in last 24 hours
serum cardiac markers
What is the usual treatment for NSTEMI?
reperfusion is NOT done for NSTEMI or UA.
aspirin, nitro, beta bloackers,

use TIMI score.

consider adding heparin, plavix, and/or glycoprotein inhibitors if TIMI is 3+.
area of heart and vessel for V1-V3 on ECG
anteroseptal, LAD
area of heart and vessel for V2-V4 on ECG
anterior
What leads are lateral on ECG?
I, avl, v 4-6
What leads are posterior on ECG
mirrored in V1, V2 (R waves)
R waves in V1 and V2
posterior infarct
What area of heart and vessel are indicated by I, avl, V4-6 on ECG?
lateral, LCA
ECG indications for reperfusion in STEMI:
1. ST elevation - what parameters?
2. What other sign?
STE > 1 mm in two contiguous leads, < 12 hours from onset

2. New left bundle branch block
How do you distinguish NSTEMI from UA?
NSTEMI will have cardiac enzyme changes, but UA will not
What are the four factors that influence coronary blood flow?
physical (aortic pressure, extravascular compression)
neural (alpha and beta receptors)
metabolic (vasodilators which increase in ischemia)
endothelial factors

Most important of these are metabolic
Prostacyclin is a [vasoconstrictor, vasodilator].
vasodilator
Endothelin - 1 is a [vasoconstrictor, vasodilator].
vasoconstrictor
Beta blockers negatively affect [contractility, heart rate, both].
both
Which calcium channel blockers are negative chronotropes?
nondihydropines
diltiazen and verapamil