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82 Cards in this Set

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What are the types of muscle?
smooth muscle
skeletal muscle (striated)
cardiac muscle (striated) (intercalated discs)
What are the four characteristics that allow muscles to function?
excitability
contractility
extensibility
elasticity
What are four important functions of muscle tissue?
Produce movement
Maintain Posture
Stabilize joints
Produce heat
What is each skeletal muscle composed of?
each skeletal muscle is an organ
composed of skeletal muscle tissue, nervous tissue, blood, connective tissue
What are three types of connective tissue involved in muscle function?
Fascia separate individual muscles
Tendons connect muscles to bones
Aponeuroses connect muscles to muscles
all are dense connective tissue
What are the 3 connective tissue coverings?
epimysium, surrounds muscles
perimysium, separates muscles into fascicles
endomysium, surrounds individual muscle fibers
What are myofibrils
threadlike proteins that provide striations
What are the proteins that form thick and thin filaments?
Actin = thin
Myosin = thick
What is a sarcomere?
Functional unit of a muscle
What is a neuromuscular junction?
Place where the nervous system and muscle system meet
Axon of a motor neuron attached to a motor end plate
What are 4 parts of a neuromuscular junction?
Synapse
Synaptic cleft
Synaptic vesicles
Neurotransmitters
What is acetylcholine (Ach)
A neurotransmitter that causes a muscle impulse
What do calcium ions do in a muscle?
bind to the troponin , changing its shape, this alters the position of the tropomysin, exposing the actin binding sites
What is the function of actin and myosin?
They bind and the muscle contracts.
What is the sliding filament model of muscle contraction?
Thick and thin filaments slide past each other causing sarcomeres to shorten
What is the cross bridge cycle?
Myosin cross bridge attaches to the actin binding site, then pivots, moving the actin filament (power stroke)
calcium ions released from sarcoplasmic reticulum, bind to troponin,
ADP and Pi are released from myosin
ATP binds to myosin, weakening the actin-myosin crossbridge, then splits into ADP and Pi, releasing energy

Myosin cross-bridge goes back to its original position (high energy position)
What are the 5 phases of muscle relaxation?
Acetylcholinesterase decomposes Ach
stimulation to sarcolemma and muscle fiber ceases
calcium ions move back into sarcoplasmic reticulum
actin and myosin binding stops
muscle relaxes
What is threshold stimulus?
minimal strength of a stimulus to cause a contraction
What is a muscle twitch?
contractile response of a single muscle fiber
What is the latent period?
length of time between stimulation and contraction
What is the all-or-none response?
Once threshold stimulus is reached, muscle fiber tends to contract completely.
generates the same force, but the force of the whole muscle must vary
What are the 3 types of muscle contractions?
Isotonic, muscle contracts and changes length
Isometric, muscle contracts but does not change length
Muscle tone, continuous state of partial contraction
What are the 3 ways ATP is regenerated in a muscle?
Direct phosphorylation of ADP by creatine phosphate
glycolysis
aerobic respiration
CP is stored in muscles to quickly convert ADP to ATP
glycolysis produces net 2 ATP
aerobic respiration produces net 32 ATP
What are the characteristics of slow-twitch fibers?
Oxidative
resistant to fatigue
red , good blood supply
many mitochondria
What are the characteristics of fast-twitch glycolytic fibers?
White , poor blood supply
susceptible to fatigue
contract rapidly
What are intermediate fibers?
Fast twitch fatigue resistant fibers
pink to red
oxidative
What is oxygen debt?
components used must be paid back, creatine, myoglobin

pyruvic acid from glycolysis converted to lactic acid
What is muscle fatigue?
muscle's inability to contract
thought to be caused by ion imbalances across the sarcolemma, decreased blood flow, buildup of lactic acid
What are cramps?
sustained involuntary muscle contraction
appear to result from decreased electrolyte concentration in extracellular fluid
How is smooth muscle different from skeletal muscle?
fibers are shorter
singular nucleus
elongated with tapering ends
lack striations
lack transverse tubules
sarcoplasmic reticula not well developed
What is origin?
More immovable end of muscle
What is insertion?
More movable end of muscle
What is a prime mover or agonist?
has the primary responsibility for movement
What are synergists?
assist the prime mover
What is an antagonist?
resists the prime mover's action
What are the 3 overlapping functions of the nervous system?
Sensory input
Integration
Motor output
Integration is moment by moment decision making about sensory information
What are the parts of the central nervous system?
Brain and spinal cord
What are the parts of the peripheral nervous system?
cranial nerves
spinal nerves (outside of the brain and spinal cord)
What does the sensory division of the peripheral nervous system do?
gets sensory info and delivers it to the cns
What does the somatic division of the motor division of the peripheral nervous system do?
carries info to glands and skeletal muscles from CNS
What does the autonomic division of the motor division of the peripheral nervous system do?
carries info to smooth muscle, cardiac muscle and glands
What are neuroglia cells?
small cells that wrap around the neurons
What are neurons?
The structural units of then nervous system
What are astrocytes?
type of neuroglia cell in the CNS
most abundant
help determine capillary permeability
connect neurons to blood vessels
mop up excess ions and neurotransmitters
what are microglia?
they monitor neuron health and move toward damaged cells
what are ependymal cells?
they are cilliated cells found in the ventricles of the brain and central canal of the spinal cord, they circulate CSF
what are oligodendrocytes?
they produce myelin sheaths for CNS neurons
what are satellite cells?
like astrocytes to PNS
what are schwann cells?
produce myelin sheaths for PNS neurons
what are the 3 structural classifications of neurons?
multipolar
bipolar
unipolar
what is the voltage of a polarized neuron?
around 70 millivolts
what are graded potentials?
short lived localized membrane changes
what are action potentials?
the primary way neurons send information over long distances
electrical changes is from +30 to -70 millivolts Na+ open, then Na+close, then K+ open
what is threshold potential?
the depolarization level needed to initiate an action potential
what is the trigger zone?
the portion of the axon where a nerve impulse originates (axonal hillock)
how does synaptic transmission work?
when an action potential passes over a synaptic knob, contents of synaptic vesicles are released because of the presence of calcium ions
what is summation?
the summing up of inhibitory postsynaptic potentials (IPSP) and excitatory postsynaptic potentials (EPSP)
what are the functions of the central nervous system?
interprets sensatios
determines perception
stores memory
reasoning/decision making
coordinates muscular movements
regulates visceral activity
determines personality
what are the major parts of the brain
cerebrum
diencephalon
brainstem
cerebellum
what are the subdivisions of the cerebrum
hemispheres
white and gray matter
basal nuclei
what are the divisions of the diencephalon?
thalamus and hypothalamus
what are the divisions of the brainstem
midbrain
pons
medulla oblongata
what are gyri
bumps
what are sulci
grooves
what is the longitudinal fissure
the point of separations of the 2 brain hemispheres
what is the transverse cerebral fissure?
separates cerebrum from cerebellum
what is the corpus callosum
the connection between cerebral hemispheres
what are the functions of the cerebrum?
interpreting impulses
initiating voluntary movements
storing memory
retreiving memories
reasoning
seat of intelligence
what is the cerebral cortex
thin layer of gray matter on the surface of the cerebrum that contains the concious mind
what are the 3 kinds of functional areas of the cerebral cortex?
sensory
motor
association
where is dopamine produced?
basal nuclei
how many pair of cranial nerves arise from the brain?
12
how many spinal nerves arise from the spinal cord?
31 pair
what is a dorsal root (posterior or sensory root)
axons of sensory neurons in dorsal root ganglion
what is the dorsal root ganglion?
cell bodies of sensory neurons whose axons conduct impulses inward from peripheral body parts
what is the ventral root (anterior or motor root)?
axons of motor neurons whose cell bodies are located in the spinal cord
what is a spinal nerve?
union of a ventral and dorsal root
what is a nerve plexus?
a complex network formed from anterior branches of spinal nerves
fibers from varius spinal nerves are sorted and recombined
what is a dermatome?
area of skin that a particular spinal nerve innervates
what is the reflex are?
complete pathway through the nervous system from stimulus to response
what are the 5 parts of the nervous system involved in a reflex arc?
receptor
sensory neuron
central neuron
motor neuron
effector
what are the 2 divisions of the autonomic nervous system?
sympathetic (fight or flight)
parasympathetic (rest and digest)