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16 Cards in this Set
- Front
- Back
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What is the pathology of Carcinoid Syndrome?
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Rare syndrome caused by carcinoid tumors, esp metastatic small bowel tumors (secrete high levels of 5-HT)
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What happens if the tumor is limited to the GI tract?
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No syndrome is seen
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What are the symptoms of Carcinoid syndrome?
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Recurrent diarrhea, cutaneous flushing, asthmatic wheezing, right-sided valvular disease
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How do you treat Carcinoid syndrome?
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Somatostatin analog (octreotide)
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What is the rule of 1/3's?
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1/3 metastasize
1/3 present with 2nd malignancy 1/3 multiple |
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What is carcinoid syndrome the most common tumor of?
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Appendix
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What is the pathology of Zollinger-Ellison syndrome?
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Gastrin-secreting tumor of pancreas or duodenum
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What are the symptoms of ZE syndrome?
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Rugal thickening with acid hypersecretion, causes recurrent ulcers
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What is ZE associated with?
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MEN type 1
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What is the major cause of Wallenberg's Syndrome?
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Caused by occlusion of one of the PICA's = unilateral infarct of lateral portion of rostral medulla
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What is lost on the contralateral body with Wallenberg's?
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Pain and temp
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What is lost on the ipsolateral face with Wallenberg's?
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Pain and temp
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What happens to the larynx with Wallenberg's?
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Hoarseness, difficulty swallowing, loss of gag reflex
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Does Horner's syndrome occur with Wallenberg's?
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Yes, ipsilaterally
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What happens to the vestibular nuclei with Wallenberg's?
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Vertigo, nystagmus, N/V
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What happens to the cerebellum with Wallenberg's?
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Ipsilateral cerebellar deficits, ataxia, past pointing
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