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15 Cards in this Set
- Front
- Back
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What is the most common cause of Hypothyroid?
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Hashimoto's Thyroiditis
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What is the pathology of Hashimotos?
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Autoimmune disorder associated with HLA-DR5
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What does Hashimoto's increase the risk of?
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Non-Hodgkin's Lymphoma
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What is seen on the histology of Hashimotos?
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Hurtle cells, lymphatic infiltrate with germinal centers
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What is the major finding of Hashimotos?
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Moderately enlarged, NONTENDER thyroid
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What is Cretinism due to?
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Severe fetal hypothyroidism
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What is the cause of endemic Cretinism?
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Where an endemic goiter is present from lack of dietary iodine
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What is the cause of sporadic cretinism?
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Defect in T4 formation or developmental failure in thyroid ormaion
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What are the 5 P's of Cretinism?
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Pot-bellied
Pale Puffy-Faced child with: Protruding Umbilicus and Protuberant tongue |
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What is Subacute Thyroiditis (de Quervain's)?
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Self-limited hypothyroidism often following a flu-like illness
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What is seen on histology of de Quervain's?
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Granulomatous inflammation
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What are the 4 findings of de Quervian's?
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Inc ESR, jaw pain, early inflammation, VERY TENDER thyroid
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What is the pathology of Riedel's Thyroiditis?
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Thyroid replaced by fibrous tissue
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What are the findings of Riedel's?
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Fixed, hard (rock-like) and PAINLESS goiter
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What are some other causes of Hypothyroidism?
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Congenital hypothyroidism, Iodine deficiency, goitrogens, Wolff-Chaikoff effect, painless thyroiditis
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